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The map label for this gene is ftsK [H]

Identifier: 125623620

GI number: 125623620

Start: 754626

End: 756893

Strand: Direct

Name: ftsK [H]

Synonym: llmg_0766

Alternate gene names: 125623620

Gene position: 754626-756893 (Clockwise)

Preceding gene: 125623618

Following gene: 125623621

Centisome position: 29.83

GC content: 37.87

Gene sequence:

>2268_bases
ATGCCTGCAAAGAAAAAAACAACTAGAAGAAATACCAAAAAAGAACTACAGAAAAAAGCCGCAACAAGGAAAATGATTGC
TTTTTTTGTTGGGCTTCTTTTAATCTTATTTGCCCTTGCTCGCTTAGGAATTGTTGGAATCTTACTTTATAATATTGTTC
GCCTGTTTATTGGTTCACTTGCCATTATTCTTCTTCTCTTAGTGGCAGCAATAATGATTCTATCAGTTTTTCGTAAGCAA
TTTTTGAAAGAAAATAAAAGAATTATTCCAGCTATTATTTTAACTTTTATTGGATTAATGTTTGTCTTTCAAATTCGACT
TCATCAGGGACTTAATGAAACTTTCCATCTTATTTGGTCTGATTTAACAGCCGGTCGAGTGATTCATTTTGTTGGTTCAG
GACTTATCGGAGCAATCATTACTGAACCCGCCAAAGCCTTGTTTTCAGTAATAGGGGTTTATATTATTGCCGCTGTTCTC
TGGCTTGTTGCTATTTATCTCATGATTCCAGGGCTCTTTCCTAAAATGCGTGAAGATTTGCATCAGCGTTTAGCAAAATG
GAAAGAAAAACGTGCAGAAAAAGTAGAAGCTAAAAAAGCCGTCAAAGCTCTTAAAAAACTGGAAGAAGAAAAAGAAATAC
CGGAGCCACAAACTATTTTGCCTGAAGCCGAAAACTCATTATTTACCTCAGCACCTGTGGAAATTCCAATCAATATTCCA
GAAGCGCCTTTTGAAGAAAATGAAAATCCAGTTTTAGAAGAAAATCCAGTCGATGATGAACCAGTGAATTTCATGAATAC
TAATAATTACAATGGAAATTATAAACTACCAACCATTGATTTATTAGCCGAAGTCCCTGTCAAAAATCAATCAGGTGAAC
GGGAAAATGTCCGCAAGAATATTGGGATTTTAGAAGAAACATTCAAATCTTTTGGAATAGGTGCCAATGTTGAATCAGCA
GTTGTTGGTCCATCAATTACCAAATATGAAATCAAATTAGCAACCGGTACAAAAGTTTCTCGTGTGGTTAATTTGTCAGA
TGACTTAGCCCTTGCTTTAGCAGCAAAAGATATTCGGATTGAAGCGCCAATTCCTGGTAAATCTTTAGTTGGTGTCGAAA
TTCCAAATGCTGAAGTTGCAATGGTTGGTTTTCGTGAGATGTGGGAAGCAGGTAAAACTAATCCTAGTAAACTCCTTGAA
ATTCCGCTTGGTAAGTCTTTAGATGGTGGAATTCGAACTTTTGATTTAACTAGAATGCCCCATTTATTGGTTGCAGGATC
GACCGGTTCTGGTAAATCAGTTGCAGTTAATGGAATTATTACTTCAATTTTGATGAAGGCTTTGCCTAGTCAAGTCAAAT
TCTTGATGGTTGACCCTAAAATGGTTGAATTATCTGTTTATAATGATATACCTCATCTATTGATTCCAGTGGTAACCAAT
CCTCGCAAAGCTTCCAGAGCGCTTCAAAAAGTTGTTGACCAAATGGAAGAACGTTATGAACTTTTCAGCCGTTATGGTGT
CAGAAATATTGCTGGTTACAATGAGAAAGTTCAAAGATATAATGCGGAATCAGATGAAAAAATGCTTGAACTTCCTTTGA
TTGTCGTTATTGTTGATGAGTTAGCCGATTTGATGATGGTTGCAAGTAAAGAAGTGGAAGATGCCATCATTCGACTCGGT
CAAAAAGCACGGGCGGCAGGGATTCACATGATTTTGGCTACCCAACGTCCATCTGTTGACGTTATTTCCGGATTAATTAA
AGCAAATGTTCCTTCACGTATCGCTTTTGCGGTTTCCTCTGGAACAGATTCACGAACAATTTTAGATACAAATGGTGCGG
AAAAATTACTTGGTCGCGGAGATATGCTTTTTAAACCAATTGATGAAAACCACCCAGTTCGTTTGCAAGGAGCTTTCTTG
TCAGATGATGATGTGGAAGCTGTTGTGACCTTTATTAAAGATCAATCAGAGGCACAATATGATGAAAGCTTTGACCCTGG
AGAAGTGGATGAGAACCAAGTGGGAACTGGGGCTTCAAATACAGGCTCAGGAGACCCGTTGTTTGAAGAGGCAAGAAACA
TGGTTATTATTGCTCAAAAAGCTTCAACGGCTCAATTACAACGTGCGCTAAAGGTTGGTTTTAATCGTGCTTCTGATTTG
ATGAATGAGCTAGAAGCGCAGGGAATTGTTGGTCCTGCTAAAGGAACAACTCCTCGTAAAGTCCTTGTTAGTCCGGATGG
AGAATTTATTGGAGGAGTAGAAGAATGA

Upstream 100 bases:

>100_bases
AGTATTTGCACAAAACGAATATTCAAAATAAACCATTTAAAAATAATAATTTGACTGACAAGTCTGTCAGTAATCTCAAA
CTCTTAGTGAAAGTAAAAAA

Downstream 100 bases:

>100_bases
GTGAAGAACTATATTATCGTCACTATTTTCTACAAATCTATGAAATTTTACGAGAAGATGAGCAAAATAAAGAACTTTCA
AGCAAGGAAAAAAATGTTTT

Product: DNA translocase ftsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MPAKKKTTRRNTKKELQKKAATRKMIAFFVGLLLILFALARLGIVGILLYNIVRLFIGSLAIILLLLVAAIMILSVFRKQ
FLKENKRIIPAIILTFIGLMFVFQIRLHQGLNETFHLIWSDLTAGRVIHFVGSGLIGAIITEPAKALFSVIGVYIIAAVL
WLVAIYLMIPGLFPKMREDLHQRLAKWKEKRAEKVEAKKAVKALKKLEEEKEIPEPQTILPEAENSLFTSAPVEIPINIP
EAPFEENENPVLEENPVDDEPVNFMNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFGIGANVESA
VVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLE
IPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTN
PRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEVEDAIIRLG
QKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPVRLQGAFL
SDDDVEAVVTFIKDQSEAQYDESFDPGEVDENQVGTGASNTGSGDPLFEEARNMVIIAQKASTAQLQRALKVGFNRASDL
MNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE

Sequences:

>Translated_755_residues
MPAKKKTTRRNTKKELQKKAATRKMIAFFVGLLLILFALARLGIVGILLYNIVRLFIGSLAIILLLLVAAIMILSVFRKQ
FLKENKRIIPAIILTFIGLMFVFQIRLHQGLNETFHLIWSDLTAGRVIHFVGSGLIGAIITEPAKALFSVIGVYIIAAVL
WLVAIYLMIPGLFPKMREDLHQRLAKWKEKRAEKVEAKKAVKALKKLEEEKEIPEPQTILPEAENSLFTSAPVEIPINIP
EAPFEENENPVLEENPVDDEPVNFMNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFGIGANVESA
VVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLE
IPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTN
PRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEVEDAIIRLG
QKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPVRLQGAFL
SDDDVEAVVTFIKDQSEAQYDESFDPGEVDENQVGTGASNTGSGDPLFEEARNMVIIAQKASTAQLQRALKVGFNRASDL
MNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
>Mature_754_residues
PAKKKTTRRNTKKELQKKAATRKMIAFFVGLLLILFALARLGIVGILLYNIVRLFIGSLAIILLLLVAAIMILSVFRKQF
LKENKRIIPAIILTFIGLMFVFQIRLHQGLNETFHLIWSDLTAGRVIHFVGSGLIGAIITEPAKALFSVIGVYIIAAVLW
LVAIYLMIPGLFPKMREDLHQRLAKWKEKRAEKVEAKKAVKALKKLEEEKEIPEPQTILPEAENSLFTSAPVEIPINIPE
APFEENENPVLEENPVDDEPVNFMNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFGIGANVESAV
VGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEI
PLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTNP
RKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEVEDAIIRLGQ
KARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPVRLQGAFLS
DDDVEAVVTFIKDQSEAQYDESFDPGEVDENQVGTGASNTGSGDPLFEEARNMVIIAQKASTAQLQRALKVGFNRASDLM
NELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=46.6531440162272, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 82963; Mature: 82832

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKKKTTRRNTKKELQKKAATRKMIAFFVGLLLILFALARLGIVGILLYNIVRLFIGSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIILLLLVAAIMILSVFRKQFLKENKRIIPAIILTFIGLMFVFQIRLHQGLNETFHLIWS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DLTAGRVIHFVGSGLIGAIITEPAKALFSVIGVYIIAAVLWLVAIYLMIPGLFPKMREDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HQRLAKWKEKRAEKVEAKKAVKALKKLEEEKEIPEPQTILPEAENSLFTSAPVEIPINIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCC
EAPFEENENPVLEENPVDDEPVNFMNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKN
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCEECCHHHHHHCCCCCCCCCCHHHHHHH
IGILEETFKSFGIGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRI
HHHHHHHHHHCCCCCCCCCHHCCCCCEEEEEEEECCCCCHHEECCCCCCEEEEEECCEEE
EAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEIPLGKSLDGGIRTFDLTRMP
ECCCCCCCEEEEECCCCCEEEHHHHHHHHCCCCCHHHEEECCCCCCCCCCCEEEECCCCC
HLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTN
EEEEECCCCCCCCEEHHHHHHHHHHHHCHHHCEEEEECCEEEEEEECCCCCCCEEECCCC
PRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCHHHHHCCHHHHHHHH
LADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSS
HHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEC
GTDSRTILDTNGAEKLLGRGDMLFKPIDENHPVRLQGAFLSDDDVEAVVTFIKDQSEAQY
CCCCCEEEECCCHHHHHCCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHCC
DESFDPGEVDENQVGTGASNTGSGDPLFEEARNMVIIAQKASTAQLQRALKVGFNRASDL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHH
MNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PAKKKTTRRNTKKELQKKAATRKMIAFFVGLLLILFALARLGIVGILLYNIVRLFIGSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIILLLLVAAIMILSVFRKQFLKENKRIIPAIILTFIGLMFVFQIRLHQGLNETFHLIWS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DLTAGRVIHFVGSGLIGAIITEPAKALFSVIGVYIIAAVLWLVAIYLMIPGLFPKMREDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HQRLAKWKEKRAEKVEAKKAVKALKKLEEEKEIPEPQTILPEAENSLFTSAPVEIPINIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEECCC
EAPFEENENPVLEENPVDDEPVNFMNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKN
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCEECCHHHHHHCCCCCCCCCCHHHHHHH
IGILEETFKSFGIGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRI
HHHHHHHHHHCCCCCCCCCHHCCCCCEEEEEEEECCCCCHHEECCCCCCEEEEEECCEEE
EAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEIPLGKSLDGGIRTFDLTRMP
ECCCCCCCEEEEECCCCCEEEHHHHHHHHCCCCCHHHEEECCCCCCCCCCCEEEECCCCC
HLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTN
EEEEECCCCCCCCEEHHHHHHHHHHHHCHHHCEEEEECCEEEEEEECCCCCCCEEECCCC
PRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDE
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCCCCCHHHHHCCHHHHHHHH
LADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSS
HHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEC
GTDSRTILDTNGAEKLLGRGDMLFKPIDENHPVRLQGAFLSDDDVEAVVTFIKDQSEAQY
CCCCCEEEECCCHHHHHCCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHCC
DESFDPGEVDENQVGTGASNTGSGDPLFEEARNMVIIAQKASTAQLQRALKVGFNRASDL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHH
MNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]