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The map label for this gene is ubiA [H]

Identifier: 125623613

GI number: 125623613

Start: 747491

End: 748450

Strand: Reverse

Name: ubiA [H]

Synonym: llmg_0759

Alternate gene names: 125623613

Gene position: 748450-747491 (Counterclockwise)

Preceding gene: 125623615

Following gene: 125623593

Centisome position: 29.59

GC content: 33.96

Gene sequence:

>960_bases
ATGTCTCTCAAATCTTTTTTAGAGCTCGTCGAAATTAAAACAAAAATTGCGAGTATTTTTCCTTATCTCATCGGTATTCT
TTTTAGTATAAGCTATTTTAAAATCCTAAATCTAGGACTTTCGCTCTTATTTTTGGTGGCTATGCTGCTTTTTGATATGA
CCGTAACTGCTATTAACAATTATCAGGATTACAAAAAGGCCAAAGATGAAAATTATAAAAAACAAGAAAACATCATCGGT
CAAGCTAACCTTTCAACTAACCTTGTTGCCTTTATAATCCTTTTGATGTTAGCCCTGAGTCTTATTCTTGGATTCTCCCT
CGCTTATTTTGTAGGTTGGCTCTTCTTTTTACTTGGTGGAATTGTCTTCTTCATTGGTGTCTTTTATACTTATGGGCCCA
TTCCGCTTTCTCGAATGCCACTAGGAGAAATCTTTTCCGGTGGTACAATGGGCTTTGGAATTTTTGCAATGGTCATTTTA
ATTAATACTTCTCAAGACCCAATTTTTAGTCTCAATTTTGATTTTACAAATAATACTTTTAGCTTAAACGGCAGTATTTT
TGCTGCTATTGCTATGATTATTGCCAGCTTACCTCTTATTTTTACCATTGCTAACATCATGCTCGCCAACAATTTACGTG
ATTTAGATACAGATATTAAGAATCACCGTTATACATTGGTTTATTATATTGGTCGCCCTTATGGCATTAAACTTTTCCAA
ATTTTGATGTATGCTTCTTATCTTGCTATTATCCTTGGCTTTTTATCTAGAATTTTTGAGTGGCCAACTTTGCTTAGCTT
GCTTACCTTCCCTATCATTAGAAAAAATCTGAAAGCACACGAGCATCAAGTACCAAGTCCGCGAAGTTTTGTTTACTCCT
TAAGAAACATGGTCTTATTTAATAGCGCCTATGCCTTTAGTCTACTTCTCTCAATCATTTGGCAATATTTAACAAAATAA

Upstream 100 bases:

>100_bases
ATATTATTAAAATGCAGAAACTTTTTTTCTCAAAAAACAAATAAATAAAAGCCGTAAAATAACGGCTGTTTTTATTAAAA
ATATATTTTCAGGAGTTTTT

Downstream 100 bases:

>100_bases
AAAAAGTGATAGATATCACTTTTTTTATTTTTCATTCAGAACCAGACGAAGCTGCTCACGAGCAAGCACTTCATCTTCCC
TTTTAATCAAAAATGTTAGA

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLKSFLELVEIKTKIASIFPYLIGILFSISYFKILNLGLSLLFLVAMLLFDMTVTAINNYQDYKKAKDENYKKQENIIG
QANLSTNLVAFIILLMLALSLILGFSLAYFVGWLFFLLGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMVIL
INTSQDPIFSLNFDFTNNTFSLNGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDTDIKNHRYTLVYYIGRPYGIKLFQ
ILMYASYLAIILGFLSRIFEWPTLLSLLTFPIIRKNLKAHEHQVPSPRSFVYSLRNMVLFNSAYAFSLLLSIIWQYLTK

Sequences:

>Translated_319_residues
MSLKSFLELVEIKTKIASIFPYLIGILFSISYFKILNLGLSLLFLVAMLLFDMTVTAINNYQDYKKAKDENYKKQENIIG
QANLSTNLVAFIILLMLALSLILGFSLAYFVGWLFFLLGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMVIL
INTSQDPIFSLNFDFTNNTFSLNGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDTDIKNHRYTLVYYIGRPYGIKLFQ
ILMYASYLAIILGFLSRIFEWPTLLSLLTFPIIRKNLKAHEHQVPSPRSFVYSLRNMVLFNSAYAFSLLLSIIWQYLTK
>Mature_318_residues
SLKSFLELVEIKTKIASIFPYLIGILFSISYFKILNLGLSLLFLVAMLLFDMTVTAINNYQDYKKAKDENYKKQENIIGQ
ANLSTNLVAFIILLMLALSLILGFSLAYFVGWLFFLLGGIVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMVILI
NTSQDPIFSLNFDFTNNTFSLNGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDTDIKNHRYTLVYYIGRPYGIKLFQI
LMYASYLAIILGFLSRIFEWPTLLSLLTFPIIRKNLKAHEHQVPSPRSFVYSLRNMVLFNSAYAFSLLLSIIWQYLTK

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 36252; Mature: 36121

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKSFLELVEIKTKIASIFPYLIGILFSISYFKILNLGLSLLFLVAMLLFDMTVTAINN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQDYKKAKDENYKKQENIIGQANLSTNLVAFIILLMLALSLILGFSLAYFVGWLFFLLGG
HHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMVILINTSQDPIFSLNFDFTNNTF
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCEE
SLNGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDTDIKNHRYTLVYYIGRPYGIKLFQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCHHHHHH
ILMYASYLAIILGFLSRIFEWPTLLSLLTFPIIRKNLKAHEHQVPSPRSFVYSLRNMVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NSAYAFSLLLSIIWQYLTK
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKSFLELVEIKTKIASIFPYLIGILFSISYFKILNLGLSLLFLVAMLLFDMTVTAINN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQDYKKAKDENYKKQENIIGQANLSTNLVAFIILLMLALSLILGFSLAYFVGWLFFLLGG
HHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVFFIGVFYTYGPIPLSRMPLGEIFSGGTMGFGIFAMVILINTSQDPIFSLNFDFTNNTF
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCEE
SLNGSIFAAIAMIIASLPLIFTIANIMLANNLRDLDTDIKNHRYTLVYYIGRPYGIKLFQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCHHHHHH
ILMYASYLAIILGFLSRIFEWPTLLSLLTFPIIRKNLKAHEHQVPSPRSFVYSLRNMVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NSAYAFSLLLSIIWQYLTK
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]