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The map label for this gene is arb [H]

Identifier: 125623605

GI number: 125623605

Start: 738330

End: 739763

Strand: Direct

Name: arb [H]

Synonym: llmg_0751

Alternate gene names: 125623605

Gene position: 738330-739763 (Clockwise)

Preceding gene: 125623604

Following gene: 125623606

Centisome position: 29.19

GC content: 37.87

Gene sequence:

>1434_bases
ATGCCATTTAGTAAAGATTTTCTCTGGGGCGGAGCTACCGCGGCTAATCAATGTGAAGGCGGCTATAATCAAGGAGGACG
TGGACTTGCTAACGTTGATCTTGTGCCTCACGGAAAAGACCGTTTTCCAATTATTACAGGGGAAATGAAGCACCTTGAAT
TTGACGAGGAACATTTCTATCCTGCAAAAGAAGCGATTGATATGTATCACCATTGGAAAGATGACCTCGCCCTTTTTGCT
GAAATGGGCTTTAAGACCTATCGAATGTCAATTGCTTGGACACGAATTTTCCCCAAAGGAGATGAACAAGAACCAAACGA
AGAAGGCTTGCAATTTTACGAAGATATTTTTAAAGAATGCAAACGTTTAGGAATTGAGCCGTTAGTTACCATTACTCACT
TTGATTGTCCAGTTCATTTGATTAAAGAATATGGGGGCTGGCGTAACCGAAAAATGGTTGGCTTTTATGAAAAACTGGCG
AGAACAATTTTTACTCGCTTTAAAGGATTGGTTCGCTATTGGCTGACATTTAATGAGATTAATATGCTACTCCATGCTCC
ATTCATGGGGGCAGGACTTGTCTTTGAAGAAGGGGAAAATAAAGAACAAGCCAAATATTTGGCTGCTCATCATGAACTTT
TGGCTTCAGCTTTGGCAACAAAAATAGCTCATGAAATTGATCCAGAAAATAAAATTGGCTGTATGTTGGCCGCTGGCGAA
TATTATCCATTTGATTGTAATCCAGAAAATGTGTTGGAAGCTCAAAAACAAAATCATGACAATCTCTTTTTCATTGATGT
CCAATCGCGTGGGAAATATCCTAACTATCTTCTAAAAAGATTAGAACGTGAGGATGTTCAACTTCCAATTGAAACGGGTG
ATTTAGAAATTTTAGCAGAAAATACTGTTGATTTTATTTCATTTAGCTATTATTCTAGTCGAGTGGCTAAGATAAAAGAC
AAGGACGCAGATAAGTCAGCTGGTAATATTTTTGAGTCTGTCACTAATCCCTATTTAAAGGCAAGTGAATGGGGCTGGCA
AATTGACCCTCTTGGACTCCGAATTACAATGAATTCTATTTATGATCGTTATCAAAAACCACTGTTTGTTGTTGAAAATG
GTTTAGGAGCTCTTGATAAACCAGATGAAAATGGCTTTGTAGCAGATGACTATCGAATTGATTATATGGCTGCTCACATC
AAAGAAATGAAAAAAGCGGTTGAACTTGATGGTGTTGAGCTACTCGGATATACTTCTTGGGGATGTATTGACTTGGTTTC
AGCAGGTACTGGTGAAATGAGTAAACGTTACGGATTCATCTATGTTGACCGAGATGATTTTGGTAAAGGAACTTTGAAAC
GGACATCTAAGAAGTCATTTGATTGGTATAAAAAAGTGATTGCAAGTAATGGTGAAGATTTAACAAATGAATGA

Upstream 100 bases:

>100_bases
TATTGAAAAAATTCTAATAAAAAACAAGATGAAATCGCTATCAAAAACAATTAAAAAATGGTAAAATGAAAAAAAGAATA
AAAAAGGAGTGTCATCTATT

Downstream 100 bases:

>100_bases
TTGATAAAAGGGGGATTTTCCCTCTTTTTTTATCAAATAAACATTTCTTTGAATTTGAGTTTTTTATCAAGCAAGAAAAA
TTTACAATAGTTAGGCAAGT

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKDDLALFA
EMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFKECKRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYEKLA
RTIFTRFKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIAHEIDPENKIGCMLAAGE
YYPFDCNPENVLEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREDVQLPIETGDLEILAENTVDFISFSYYSSRVAKIKD
KDADKSAGNIFESVTNPYLKASEWGWQIDPLGLRITMNSIYDRYQKPLFVVENGLGALDKPDENGFVADDYRIDYMAAHI
KEMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDFGKGTLKRTSKKSFDWYKKVIASNGEDLTNE

Sequences:

>Translated_477_residues
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKDDLALFA
EMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFKECKRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYEKLA
RTIFTRFKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIAHEIDPENKIGCMLAAGE
YYPFDCNPENVLEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREDVQLPIETGDLEILAENTVDFISFSYYSSRVAKIKD
KDADKSAGNIFESVTNPYLKASEWGWQIDPLGLRITMNSIYDRYQKPLFVVENGLGALDKPDENGFVADDYRIDYMAAHI
KEMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDFGKGTLKRTSKKSFDWYKKVIASNGEDLTNE
>Mature_476_residues
PFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFYPAKEAIDMYHHWKDDLALFAE
MGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFKECKRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYEKLAR
TIFTRFKGLVRYWLTFNEINMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIAHEIDPENKIGCMLAAGEY
YPFDCNPENVLEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREDVQLPIETGDLEILAENTVDFISFSYYSSRVAKIKDK
DADKSAGNIFESVTNPYLKASEWGWQIDPLGLRITMNSIYDRYQKPLFVVENGLGALDKPDENGFVADDYRIDYMAAHIK
EMKKAVELDGVELLGYTSWGCIDLVSAGTGEMSKRYGFIYVDRDDFGKGTLKRTSKKSFDWYKKVIASNGEDLTNE

Specific function: Can hydrolyze salicin, cellobiose, and probably arbutin [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=502, Percent_Identity=28.0876494023904, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI32481206, Length=491, Percent_Identity=27.6985743380855, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI13273313, Length=495, Percent_Identity=27.6767676767677, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=27.9835390946502, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI28376633, Length=488, Percent_Identity=26.2295081967213, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1789070, Length=472, Percent_Identity=61.0169491525424, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI2367174, Length=481, Percent_Identity=53.2224532224532, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=51.271186440678, Blast_Score=497, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17552856, Length=489, Percent_Identity=29.4478527607362, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=29.0983606557377, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356577, Length=502, Percent_Identity=24.9003984063745, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54729; Mature: 54597

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFY
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHCCCCCHHHCC
PAKEAIDMYHHWKDDLALFAEMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFKEC
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
KRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYEKLARTIFTRFKGLVRYWLTFNEI
HHCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIAHEIDPENKIGCMLAAGE
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
YYPFDCNPENVLEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREDVQLPIETGDLEILAE
CCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEEC
NTVDFISFSYYSSRVAKIKDKDADKSAGNIFESVTNPYLKASEWGWQIDPLGLRITMNSI
CCCHHEEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEECCCCCCEECCCEEEEEHHHH
YDRYQKPLFVVENGLGALDKPDENGFVADDYRIDYMAAHIKEMKKAVELDGVELLGYTSW
HHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
GCIDLVSAGTGEMSKRYGFIYVDRDDFGKGTLKRTSKKSFDWYKKVIASNGEDLTNE
CHHHHHCCCCCCHHHCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PFSKDFLWGGATAANQCEGGYNQGGRGLANVDLVPHGKDRFPIITGEMKHLEFDEEHFY
CCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHCCCCCHHHCC
PAKEAIDMYHHWKDDLALFAEMGFKTYRMSIAWTRIFPKGDEQEPNEEGLQFYEDIFKEC
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
KRLGIEPLVTITHFDCPVHLIKEYGGWRNRKMVGFYEKLARTIFTRFKGLVRYWLTFNEI
HHCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NMLLHAPFMGAGLVFEEGENKEQAKYLAAHHELLASALATKIAHEIDPENKIGCMLAAGE
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
YYPFDCNPENVLEAQKQNHDNLFFIDVQSRGKYPNYLLKRLEREDVQLPIETGDLEILAE
CCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEEC
NTVDFISFSYYSSRVAKIKDKDADKSAGNIFESVTNPYLKASEWGWQIDPLGLRITMNSI
CCCHHEEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEECCCCCCEECCCEEEEEHHHH
YDRYQKPLFVVENGLGALDKPDENGFVADDYRIDYMAAHIKEMKKAVELDGVELLGYTSW
HHHHCCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
GCIDLVSAGTGEMSKRYGFIYVDRDDFGKGTLKRTSKKSFDWYKKVIASNGEDLTNE
CHHHHHCCCCCCHHHCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1630307; 9278503 [H]