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The map label for this gene is ptnC [H]

Identifier: 125623583

GI number: 125623583

Start: 710538

End: 711350

Strand: Reverse

Name: ptnC [H]

Synonym: llmg_0728

Alternate gene names: 125623583

Gene position: 711350-710538 (Counterclockwise)

Preceding gene: 125623584

Following gene: 125623582

Centisome position: 28.12

GC content: 46.62

Gene sequence:

>813_bases
ATGGAATACGGTGTTTTATCTGTAATCTTGGTCATTCTCGTTGCCTTCCTTGCTGGTCTTGAAGGTATCCTTGACCAATG
GCAATTCCACCAACCAATTATCGCCTGCTCGCTCATCGGTATTGTTACTGGTCACGCATCTGCAGGGATTATCCTCGGTG
GTTCGCTTCAATTGATCGCTCTTGGTTGGGCTAACGTTGGTGCCGCTGTCGCACCCGATGCTGCCCTTGCCTCAATCGCC
TCATCTATTTTGATGGTTCAATCAAACAACTTTGATTTGACTCACATCATGGGTACTATCGTTCCTGCTGCTATCTTGCT
TGCAACTGCTGGTCTTGTATTGACTACTCTTGTACGTATGCTTTCAGTTGTGCTCGTTCACCAAGCTGACCGTGCTGCGG
AAAATGGTTCTTACTCAGGTGTTGAAATGTGGCACTTCATCGCGCTTATCTGTCAAGGTTTGCGTATCGCTATCCCTGCT
GGACTTCTTTTGGTTATCTCACCTGAAGCTATCCAAAACGCACTTGCTGCTATTCCTCCAGTTATCTCTGGTGGTCTTGC
TGTCGGTGGTGGGATGGTTGTTGCCGTTGGTTATGCAATGGTTATCAACCTTATGGCTACTCGTGAAGTATGGCCTTTCT
TCTTCCTTGGTTTCGCTCTCGCACCAATCTCTGAATTAACATTGATTGCAACTGGTGTCCTCGGTGTTGTTATCGCTATC
GTTTACCTTAACCTTCAATCTTCTGGTGGTTCTGGAAATGGTACTGCATCATCATCAGGTGACCCAATTGGCGACATCTT
GAACGACTACTAA

Upstream 100 bases:

>100_bases
TAAAAAAGCTAACGTACAATAATCAGAATATGCTCGTCTGATATTCTGATTAATAAAATTGAATATTAGGCAGCTAATTA
ATTAAGGAGATATAAAAAAC

Downstream 100 bases:

>100_bases
GAAAGGAGGATCTAAAAAATGTCTGATAAAAAAGTAACTCTTGATAAGAAAATCCGTCGTAGCGTTATGTGGCGTTCAAT
GTTCCTCCAAGGTTCTTGGA

Product: mannose-specific PTS system component IIC

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MEYGVLSVILVILVAFLAGLEGILDQWQFHQPIIACSLIGIVTGHASAGIILGGSLQLIALGWANVGAAVAPDAALASIA
SSILMVQSNNFDLTHIMGTIVPAAILLATAGLVLTTLVRMLSVVLVHQADRAAENGSYSGVEMWHFIALICQGLRIAIPA
GLLLVISPEAIQNALAAIPPVISGGLAVGGGMVVAVGYAMVINLMATREVWPFFFLGFALAPISELTLIATGVLGVVIAI
VYLNLQSSGGSGNGTASSSGDPIGDILNDY

Sequences:

>Translated_270_residues
MEYGVLSVILVILVAFLAGLEGILDQWQFHQPIIACSLIGIVTGHASAGIILGGSLQLIALGWANVGAAVAPDAALASIA
SSILMVQSNNFDLTHIMGTIVPAAILLATAGLVLTTLVRMLSVVLVHQADRAAENGSYSGVEMWHFIALICQGLRIAIPA
GLLLVISPEAIQNALAAIPPVISGGLAVGGGMVVAVGYAMVINLMATREVWPFFFLGFALAPISELTLIATGVLGVVIAI
VYLNLQSSGGSGNGTASSSGDPIGDILNDY
>Mature_270_residues
MEYGVLSVILVILVAFLAGLEGILDQWQFHQPIIACSLIGIVTGHASAGIILGGSLQLIALGWANVGAAVAPDAALASIA
SSILMVQSNNFDLTHIMGTIVPAAILLATAGLVLTTLVRMLSVVLVHQADRAAENGSYSGVEMWHFIALICQGLRIAIPA
GLLLVISPEAIQNALAAIPPVISGGLAVGGGMVVAVGYAMVINLMATREVWPFFFLGFALAPISELTLIATGVLGVVIAI
VYLNLQSSGGSGNGTASSSGDPIGDILNDY

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=246, Percent_Identity=48.3739837398374, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789528, Length=248, Percent_Identity=21.7741935483871, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27593; Mature: 27593

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYGVLSVILVILVAFLAGLEGILDQWQFHQPIIACSLIGIVTGHASAGIILGGSLQLIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCEEEEE
LGWANVGAAVAPDAALASIASSILMVQSNNFDLTHIMGTIVPAAILLATAGLVLTTLVRM
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVVLVHQADRAAENGSYSGVEMWHFIALICQGLRIAIPAGLLLVISPEAIQNALAAIPP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHCCH
VISGGLAVGGGMVVAVGYAMVINLMATREVWPFFFLGFALAPISELTLIATGVLGVVIAI
HHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLNLQSSGGSGNGTASSSGDPIGDILNDY
HHHHEECCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MEYGVLSVILVILVAFLAGLEGILDQWQFHQPIIACSLIGIVTGHASAGIILGGSLQLIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCEEEEE
LGWANVGAAVAPDAALASIASSILMVQSNNFDLTHIMGTIVPAAILLATAGLVLTTLVRM
EECCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVVLVHQADRAAENGSYSGVEMWHFIALICQGLRIAIPAGLLLVISPEAIQNALAAIPP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHCCH
VISGGLAVGGGMVVAVGYAMVINLMATREVWPFFFLGFALAPISELTLIATGVLGVVIAI
HHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLNLQSSGGSGNGTASSSGDPIGDILNDY
HHHHEECCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]