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The map label for this gene is ptsK

Identifier: 125623444

GI number: 125623444

Start: 570276

End: 571208

Strand: Direct

Name: ptsK

Synonym: llmg_0582

Alternate gene names: 125623444

Gene position: 570276-571208 (Clockwise)

Preceding gene: 125623443

Following gene: 125623445

Centisome position: 22.55

GC content: 39.44

Gene sequence:

>933_bases
ATGGCGGTTTCAGTTCAAGACTTACTTGATAAAATTCACTTTCATGTGATTTACTCAACAGAAACAGCATTACAAAAAGA
AATTACAACTTCCGAAATTATGCGGCCAGGTTTAGAAATGGCTGGTTATTTTGATTACTTCACCCCTGAGCGAATTCAGC
TTTTTGGGATGAAAGAGTGGTCTTACATGATGACTGTAGTCGGAGATAATCGTTATGACCTTTTAAAAAAGGTCATGGCC
AAAGAAACACCAGTTGTGATTGTTGCGCGTAATTTAGAAATTCCAAGTGAAATGGTTGCAGCAGCTAAAAAAGCAGATAT
TGTCTTGCTTCAATCACGGGAAGCAACCAGTCGTTTAAACTCGGTTTTGACTTCATTCCTTGATGAACGTTTAGCAGAAA
GAACCACAGTTCATGGTGTTTTGATGGATATTTTTGGCGTTGGTGTGCTGATTCAAGGTGCGAGTGGGATTGGTAAATCT
GAAACAGGTCTTGAATTAGTTAAACGAGGTCACCGATTAGTTGCTGATGACCGTGTAGACGTTTTTCAACGAGATGCTTT
TACGCTTTCTGGAGAACCTGCAGAAATTTTGCGCAATATGATAGAAATTCGTGGCGTTGGGATTATTGACGTGATGAGTC
TTTTTGGTGCAGGTGCTGTCAAGGATTCAACGGATATTGATATGGCTATCTATTTAGAATATTACGATAAAGAAAAAGCT
TTTGATCGTTTGGGAAATGCGCCGACAATCGTCGAATTTTCTGATGTTGAAGTGCCTCAAACGCGTATTCCTGTAAAAAC
AGGGCGTAATGTGTCAGTGATTGTTGAAGCGGCAGTCATGAATTTCAGAGCTAAACAAATGGGCTTTGATGCAACCAAAA
CTTTTGAAGACCGTCTAACAGACTTGATCAGTCACAACAAAGAATCACAATAA

Upstream 100 bases:

>100_bases
GACAAAATTTGTGGAGACTTGTAAGTAAAAAAATATGATATTATTCTCTAGCAATTCTGTCAGTTATTCTTAATTTATGA
AAAAATAAGGGAGAATTAAA

Downstream 100 bases:

>100_bases
AACTTAGAGGTAACTGACAGACAGAAATACTGTCAGTTAAAATGGAAAACTGATAAAAACTATGAATAATTTATTTCCTT
TTTTAGCTCTGGATAAAATT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEWSYMMTVVGDNRYDLLKKVMA
KETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLNSVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKS
ETGLELVKRGHRLVADDRVDVFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKA
FDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLTDLISHNKESQ

Sequences:

>Translated_310_residues
MAVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEWSYMMTVVGDNRYDLLKKVMA
KETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLNSVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKS
ETGLELVKRGHRLVADDRVDVFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKA
FDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLTDLISHNKESQ
>Mature_309_residues
AVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEWSYMMTVVGDNRYDLLKKVMAK
ETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLNSVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKSE
TGLELVKRGHRLVADDRVDVFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKAF
DRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLTDLISHNKESQ

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_LACLM (A2RIT6)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001031927.1
- ProteinModelPortal:   A2RIT6
- SMR:   A2RIT6
- STRING:   A2RIT6
- GeneID:   4798577
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0582
- eggNOG:   COG1493
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34654; Mature: 34523

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: ACT_SITE 138-138 ACT_SITE 159-159 ACT_SITE 177-177 ACT_SITE 243-243

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEW
CCCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCC
SYMMTVVGDNRYDLLKKVMAKETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLN
EEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHH
SVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCEEEECCCHH
VFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKA
HHHCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHH
FDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLT
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHH
DLISHNKESQ
HHHHCCCCCC
>Mature Secondary Structure 
AVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEW
CCCHHHHHHHHHEEEEEECHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEEECCCC
SYMMTVVGDNRYDLLKKVMAKETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLN
EEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHH
SVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCEEEECCCHH
VFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMAIYLEYYDKEKA
HHHCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHH
FDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLT
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHH
DLISHNKESQ
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA