Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 125623403

GI number: 125623403

Start: 535174

End: 536295

Strand: Direct

Name: argE [H]

Synonym: llmg_0536

Alternate gene names: 125623403

Gene position: 535174-536295 (Clockwise)

Preceding gene: 125623402

Following gene: 125623405

Centisome position: 21.16

GC content: 37.43

Gene sequence:

>1122_bases
ATGGAAAAAGCGGTAGAATTGTTAAAAAGTTTGGTTGATATTCCATCAAGTTCAGGAAATGAATCAGAAATCTTAATCTA
TCTTGAAAAGTGGTTGATTAAAGAAGGATTTGATTTTGTTGTTCGTGAGGAAACTTTTGTTGCTGGGCAGATTAAGGCAA
ATGTTAATAATGGACAAAAAAAAGAAGCCATTATCCTAGCTGGTCATGTTGATACTGTAGTTGCCGGGAATTTGTGCGAT
TGGAAATTTCCCCCTACTGATGCTCAAGTGAAAGAGGGAAAACTCTTTGGACTTGGTGCTAGTGACATGAAGGGCGGCGA
TGTTGGGAATTTACTTGCTGCTGCAAGTTTTATCGGTCAAGATTTAAGTCAAGATATCTGGGTCGTTGGGACTGCTAACG
AAGAGCTCGACGGGAAGGGTTCGGAAGATTTTGCTCGATATTTCAGTCAAAATTGCTCTTATGAGTCTGCACTTTGTATT
ATTGCAGAACCTACTGATTTAGAGAAGATTTATATTGGACAACGTGGAAATCATTTTATGAAGCTGCATTTTTCTGGAAA
GGCTGGTCATGCTTCGGTACAAGAGCATTTTCAAGAAAGTGCTTTAGGTGATGTTACTTATTTTTTGGCAAATATTGAAC
AGATTTTTGAAGAGTTGAAGACTTATAGAAATAGTCAACTATATGTGCCGACTTTTGTTGTGACATCTATTTATGCCGGT
GATGAGAAGTCTCCCAATAAAACAGCTGATTTTGCTGATCTGGTTGTTGACTGCCGATTGACACCTGAACTGGAGTTAGT
TTTTGAACAAGTAATGATTGATTTAGCGGCCAAATATCATTTTACTTACGAGGATATTGTTACACCTGTTTTATCAACTT
TGACGGATAATCAAGTCCCCTTTATCCAATTGCTGACTGACTTATCAGGAGCACAAACGACAGGGGCCTCAGGCTCTAAT
GACCAAGGATTTTTTGAAAATGTTGGAATCAGAACAGTTGTTTTTGGGCCTGGTCAGCATGACCAATGTCATATTGCTAA
TGAGTATATTCTATTGGAAAAGCTAGAGAAGCATATTGAAATTTTACAATCATTCATCAAAAAAATACAAGAAATTTACT
GA

Upstream 100 bases:

>100_bases
ATTCTGTGATTAAAGAAGAATTAAAGAATGGACAAATTAATAAAGATATTCAAAAGAACTATACTCTTTCTGAAAATAAC
AAATAGTTTGGTGGAAATTT

Downstream 100 bases:

>100_bases
CAGAGCCGTTCTAACTAAAAAAATTACTGACAAGTTCTGTCAGTAATTTTTTTAGTTAGTTTGTTCAGCTGCTTCATCAA
CGATAAAGGTAAACTGACAA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MEKAVELLKSLVDIPSSSGNESEILIYLEKWLIKEGFDFVVREETFVAGQIKANVNNGQKKEAIILAGHVDTVVAGNLCD
WKFPPTDAQVKEGKLFGLGASDMKGGDVGNLLAAASFIGQDLSQDIWVVGTANEELDGKGSEDFARYFSQNCSYESALCI
IAEPTDLEKIYIGQRGNHFMKLHFSGKAGHASVQEHFQESALGDVTYFLANIEQIFEELKTYRNSQLYVPTFVVTSIYAG
DEKSPNKTADFADLVVDCRLTPELELVFEQVMIDLAAKYHFTYEDIVTPVLSTLTDNQVPFIQLLTDLSGAQTTGASGSN
DQGFFENVGIRTVVFGPGQHDQCHIANEYILLEKLEKHIEILQSFIKKIQEIY

Sequences:

>Translated_373_residues
MEKAVELLKSLVDIPSSSGNESEILIYLEKWLIKEGFDFVVREETFVAGQIKANVNNGQKKEAIILAGHVDTVVAGNLCD
WKFPPTDAQVKEGKLFGLGASDMKGGDVGNLLAAASFIGQDLSQDIWVVGTANEELDGKGSEDFARYFSQNCSYESALCI
IAEPTDLEKIYIGQRGNHFMKLHFSGKAGHASVQEHFQESALGDVTYFLANIEQIFEELKTYRNSQLYVPTFVVTSIYAG
DEKSPNKTADFADLVVDCRLTPELELVFEQVMIDLAAKYHFTYEDIVTPVLSTLTDNQVPFIQLLTDLSGAQTTGASGSN
DQGFFENVGIRTVVFGPGQHDQCHIANEYILLEKLEKHIEILQSFIKKIQEIY
>Mature_373_residues
MEKAVELLKSLVDIPSSSGNESEILIYLEKWLIKEGFDFVVREETFVAGQIKANVNNGQKKEAIILAGHVDTVVAGNLCD
WKFPPTDAQVKEGKLFGLGASDMKGGDVGNLLAAASFIGQDLSQDIWVVGTANEELDGKGSEDFARYFSQNCSYESALCI
IAEPTDLEKIYIGQRGNHFMKLHFSGKAGHASVQEHFQESALGDVTYFLANIEQIFEELKTYRNSQLYVPTFVVTSIYAG
DEKSPNKTADFADLVVDCRLTPELELVFEQVMIDLAAKYHFTYEDIVTPVLSTLTDNQVPFIQLLTDLSGAQTTGASGSN
DQGFFENVGIRTVVFGPGQHDQCHIANEYILLEKLEKHIEILQSFIKKIQEIY

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=382, Percent_Identity=23.2984293193717, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789236, Length=263, Percent_Identity=26.2357414448669, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41360; Mature: 41360

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAVELLKSLVDIPSSSGNESEILIYLEKWLIKEGFDFVVREETFVAGQIKANVNNGQK
CCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHCCCCEEEECCEEEEEEEEECCCCCCC
KEAIILAGHVDTVVAGNLCDWKFPPTDAQVKEGKLFGLGASDMKGGDVGNLLAAASFIGQ
CCEEEEECCHHHHEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
DLSQDIWVVGTANEELDGKGSEDFARYFSQNCSYESALCIIAEPTDLEKIYIGQRGNHFM
CCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEE
KLHFSGKAGHASVQEHFQESALGDVTYFLANIEQIFEELKTYRNSQLYVPTFVVTSIYAG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHEEHHEECC
DEKSPNKTADFADLVVDCRLTPELELVFEQVMIDLAAKYHFTYEDIVTPVLSTLTDNQVP
CCCCCCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
FIQLLTDLSGAQTTGASGSNDQGFFENVGIRTVVFGPGQHDQCHIANEYILLEKLEKHIE
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHH
ILQSFIKKIQEIY
HHHHHHHHHHHHC
>Mature Secondary Structure
MEKAVELLKSLVDIPSSSGNESEILIYLEKWLIKEGFDFVVREETFVAGQIKANVNNGQK
CCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHCCCCEEEECCEEEEEEEEECCCCCCC
KEAIILAGHVDTVVAGNLCDWKFPPTDAQVKEGKLFGLGASDMKGGDVGNLLAAASFIGQ
CCEEEEECCHHHHEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
DLSQDIWVVGTANEELDGKGSEDFARYFSQNCSYESALCIIAEPTDLEKIYIGQRGNHFM
CCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCEEE
KLHFSGKAGHASVQEHFQESALGDVTYFLANIEQIFEELKTYRNSQLYVPTFVVTSIYAG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHEEHHEECC
DEKSPNKTADFADLVVDCRLTPELELVFEQVMIDLAAKYHFTYEDIVTPVLSTLTDNQVP
CCCCCCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
FIQLLTDLSGAQTTGASGSNDQGFFENVGIRTVVFGPGQHDQCHIANEYILLEKLEKHIE
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHH
ILQSFIKKIQEIY
HHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA