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The map label for this gene is murA2 [H]

Identifier: 125623384

GI number: 125623384

Start: 508088

End: 509368

Strand: Direct

Name: murA2 [H]

Synonym: llmg_0517

Alternate gene names: 125623384

Gene position: 508088-509368 (Clockwise)

Preceding gene: 125623383

Following gene: 125623385

Centisome position: 20.09

GC content: 39.27

Gene sequence:

>1281_bases
ATGGATAAAATAATTGTAAAAGGTGGGCAAACAAAACTTCAAGGAGAAGTCGAAATTGAAGGAGCAAAAAATGCTGTTCT
TCCACTTCTTGCCGCTACTTTACTTGCTAGTGAAGGCGAAGTTGTATTAACTAATGTCCCTATTTTAAGTGATGTTTTTA
TGATGAATAATTTAGTAGATCATCTAGGGACGAGCATTAGTTTTGACCAGGAAGCAAAGAAAATCATTGCTAAAGCTAAT
TCTGAAATAAAAACAACTGCCCCTTATGAGTATGTCAGCAAAATGCGAGCATCTATTGTTGTCATGGGACCAATTTTAGC
TAGAAATGGCCAAGCGCGGGTTTCTATGCCAGGAGGATGTTCAATTGGTTCACGTCCAATCGATTTACATTTGCGTGGAT
TTGAGCAAATGGGAGCAACAATTACTCAAAATGCTGGTTATATTGAAGCTAAGGCTGATAAATTAAAAGGAGCTCACATA
TATCTTGATTTCCCTTCAGTAGGAGCCACGCAAAATCTAATTCTTGCGGCTACCTTAGCCGAAGGAGTAACAACACTCGA
AAATGCGGCCCGCGAACCAGAAATCGTTGACTTAGCCAATCTTTTGAACAAAATGGGTGCAAATGTTAAGGGCGCTGGGA
CTGATACAATCATAATCAAAGGTGTTGAAAAAATGCACGGTGCAAAACACTCTGTTGTTCAAGATCGAATTGAAGCCGGA
ACTTTCATGGTTGCAGCAGCAATGACCCAAGGTGATGTACTAATTAAAGATGCAATTGCTGAGCATAATCGTCCATTAAT
ATCAAAACTCAGTGAAATGGGCGTTAATTTCACTCAAGAAGAAACAGGACTTAGAGTCGTAGGGCCTGAAAAACTCAAAG
CTACTAGTGTTAAAACATTGCCACACCCAGGTTTTCCAACTGATATGCAATCTCAAATGACCGCCGCTCAAGCGATCGCA
GCTGGAGAATCTGTAATGGTCGAAACAGTATTTGAAAATCGGTTCCAACATTTAGAAGAAATGCGTCGTATGGGATTGGA
AGTAGATATTACTAGAAATACAGCCTTAATCCAAGGAAATTCAAATTTGCAAGGAGCCGCAGTAAAATCAACAGATTTAA
GAGCGAGTGCAGCTTTGATTCTTTTAGGATTAGTGGCTAAAGGCCAAACAACTGTAAGAAGATTAAGTCACTTAGACCGC
GGTTATTATAAATTCCATGAAAAATTAAAAGCACTTGGTGCTGATATTGTCCGAGTGAAAGATGAAGACGGAGAAGAATA
A

Upstream 100 bases:

>100_bases
AGTTAAAACAAATGAAATGTTTCAGCAAAATAGAATGTTCTTTTATGATATAATTTAAAAATATAAATTAAAAATAGAGG
AAAAATAGGAATTTAAATAA

Downstream 100 bases:

>100_bases
TGTTCAAGAAGACCATAAAATTTTTAGGACTAAGATTATCAATTATCATTTTTGTTATCATTTTGTTAGTCCTTGCCATT
GTTTTAGGGCTAATGGTTGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDKIIVKGGQTKLQGEVEIEGAKNAVLPLLAATLLASEGEVVLTNVPILSDVFMMNNLVDHLGTSISFDQEAKKIIAKAN
SEIKTTAPYEYVSKMRASIVVMGPILARNGQARVSMPGGCSIGSRPIDLHLRGFEQMGATITQNAGYIEAKADKLKGAHI
YLDFPSVGATQNLILAATLAEGVTTLENAAREPEIVDLANLLNKMGANVKGAGTDTIIIKGVEKMHGAKHSVVQDRIEAG
TFMVAAAMTQGDVLIKDAIAEHNRPLISKLSEMGVNFTQEETGLRVVGPEKLKATSVKTLPHPGFPTDMQSQMTAAQAIA
AGESVMVETVFENRFQHLEEMRRMGLEVDITRNTALIQGNSNLQGAAVKSTDLRASAALILLGLVAKGQTTVRRLSHLDR
GYYKFHEKLKALGADIVRVKDEDGEE

Sequences:

>Translated_426_residues
MDKIIVKGGQTKLQGEVEIEGAKNAVLPLLAATLLASEGEVVLTNVPILSDVFMMNNLVDHLGTSISFDQEAKKIIAKAN
SEIKTTAPYEYVSKMRASIVVMGPILARNGQARVSMPGGCSIGSRPIDLHLRGFEQMGATITQNAGYIEAKADKLKGAHI
YLDFPSVGATQNLILAATLAEGVTTLENAAREPEIVDLANLLNKMGANVKGAGTDTIIIKGVEKMHGAKHSVVQDRIEAG
TFMVAAAMTQGDVLIKDAIAEHNRPLISKLSEMGVNFTQEETGLRVVGPEKLKATSVKTLPHPGFPTDMQSQMTAAQAIA
AGESVMVETVFENRFQHLEEMRRMGLEVDITRNTALIQGNSNLQGAAVKSTDLRASAALILLGLVAKGQTTVRRLSHLDR
GYYKFHEKLKALGADIVRVKDEDGEE
>Mature_426_residues
MDKIIVKGGQTKLQGEVEIEGAKNAVLPLLAATLLASEGEVVLTNVPILSDVFMMNNLVDHLGTSISFDQEAKKIIAKAN
SEIKTTAPYEYVSKMRASIVVMGPILARNGQARVSMPGGCSIGSRPIDLHLRGFEQMGATITQNAGYIEAKADKLKGAHI
YLDFPSVGATQNLILAATLAEGVTTLENAAREPEIVDLANLLNKMGANVKGAGTDTIIIKGVEKMHGAKHSVVQDRIEAG
TFMVAAAMTQGDVLIKDAIAEHNRPLISKLSEMGVNFTQEETGLRVVGPEKLKATSVKTLPHPGFPTDMQSQMTAAQAIA
AGESVMVETVFENRFQHLEEMRRMGLEVDITRNTALIQGNSNLQGAAVKSTDLRASAALILLGLVAKGQTTVRRLSHLDR
GYYKFHEKLKALGADIVRVKDEDGEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=49.2924528301887, Blast_Score=393, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45732; Mature: 45732

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIVKGGQTKLQGEVEIEGAKNAVLPLLAATLLASEGEVVLTNVPILSDVFMMNNLVD
CCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
HLGTSISFDQEAKKIIAKANSEIKTTAPYEYVSKMRASIVVMGPILARNGQARVSMPGGC
HHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEEECHHHCCCCCEEEECCCCC
SIGSRPIDLHLRGFEQMGATITQNAGYIEAKADKLKGAHIYLDFPSVGATQNLILAATLA
CCCCCCEEEEECCHHHHCCEEECCCCEEEECHHHCCCCEEEEECCCCCCCCCCEEEHHHH
EGVTTLENAAREPEIVDLANLLNKMGANVKGAGTDTIIIKGVEKMHGAKHSVVQDRIEAG
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCCHHHHHHHHHHCC
TFMVAAAMTQGDVLIKDAIAEHNRPLISKLSEMGVNFTQEETGLRVVGPEKLKATSVKTL
CEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCEEEECCCHHHHCCCCCC
PHPGFPTDMQSQMTAAQAIAAGESVMVETVFENRFQHLEEMRRMGLEVDITRNTALIQGN
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECC
SNLQGAAVKSTDLRASAALILLGLVAKGQTTVRRLSHLDRGYYKFHEKLKALGADIVRVK
CCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DEDGEE
CCCCCC
>Mature Secondary Structure
MDKIIVKGGQTKLQGEVEIEGAKNAVLPLLAATLLASEGEVVLTNVPILSDVFMMNNLVD
CCCEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
HLGTSISFDQEAKKIIAKANSEIKTTAPYEYVSKMRASIVVMGPILARNGQARVSMPGGC
HHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEEECHHHCCCCCEEEECCCCC
SIGSRPIDLHLRGFEQMGATITQNAGYIEAKADKLKGAHIYLDFPSVGATQNLILAATLA
CCCCCCEEEEECCHHHHCCEEECCCCEEEECHHHCCCCEEEEECCCCCCCCCCEEEHHHH
EGVTTLENAAREPEIVDLANLLNKMGANVKGAGTDTIIIKGVEKMHGAKHSVVQDRIEAG
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCCHHHHHHHHHHCC
TFMVAAAMTQGDVLIKDAIAEHNRPLISKLSEMGVNFTQEETGLRVVGPEKLKATSVKTL
CEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCEEEECCCHHHHCCCCCC
PHPGFPTDMQSQMTAAQAIAAGESVMVETVFENRFQHLEEMRRMGLEVDITRNTALIQGN
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECC
SNLQGAAVKSTDLRASAALILLGLVAKGQTTVRRLSHLDRGYYKFHEKLKALGADIVRVK
CCCCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DEDGEE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]