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The map label for this gene is hly [C]

Identifier: 125623358

GI number: 125623358

Start: 485703

End: 486356

Strand: Reverse

Name: hly [C]

Synonym: llmg_0491

Alternate gene names: 125623358

Gene position: 486356-485703 (Counterclockwise)

Preceding gene: 125623364

Following gene: 125623347

Centisome position: 19.23

GC content: 38.53

Gene sequence:

>654_bases
ATGGAAGAAACACAAGGTTCAAGAACCTATCAGATTCTCAATGAGATTTTCAATGCGATAACTCATGGAGCAGGAACCGG
CTTAGCAATTGCCGCCTTAGTTCTTCTCGTGATTAAAGGTGCTGCTTCTGGGTCTGCACTTGAAGTTGTTGCTTTTACAA
TCTATGGAGCCTCATTAGTAATTCTTTTTCTGTGTTCCACATTAGCACACAGTTTACATTTTACTAAAGCGGTCAAAGTT
TTTCGAGTTTTTGACCATAACGGGATATTCTTTTTAATTGCTGGAACCTACACGCCTTACTGTTTAGTTGCTTTAAATAA
TTGGTTAGGTTGGATTGTGCTAGCAGTGATTTGGATTTGTTCTATTTTGGGGATTGTCTTAACTTCAATTTACTTGCCAA
AATGGGGTAAAACACCTAAATTATCAACTGTTTTATATGTTGTTCTTGGTTGGATGATTTTGATTGTCATTTATCCTTTA
TGGAATGCCCTACATCCAGTTGGCTTCTGGCTTTTAGTTGCAGGAGGCGTGGTTTATTCCGTCGGAGCGCTTGTCTATCA
CTTTAAATTTCCTTTCGCTCACGTGGTTTGGCACCTCTTTGTTTTACTAGCTGCAATCCTCATGTTCTTCTCTGTTTATC
TTTATGTGGGATAA

Upstream 100 bases:

>100_bases
TGGAAAGAGCAAAAAAGGTTGAAAATATTATTTTTTTGATTTCAAAACAAATCATAAAATTGCTCAAAAGCTGAATAAAT
CAATAAATTGGAGAGAACAA

Downstream 100 bases:

>100_bases
AATAAAAAACCGTTTGCTAAGCGGTTTTTTTATTTTTCTCCGTCCATTCGAACGCCTTGTAAGAAATAACGATTAAATAT
AATATACAAAATGATAATAG

Product: hemolysin like protein

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MEETQGSRTYQILNEIFNAITHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHSLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALHPVGFWLLVAGGVVYSVGALVYHFKFPFAHVVWHLFVLLAAILMFFSVYLYVG

Sequences:

>Translated_217_residues
MEETQGSRTYQILNEIFNAITHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHSLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALHPVGFWLLVAGGVVYSVGALVYHFKFPFAHVVWHLFVLLAAILMFFSVYLYVG
>Mature_217_residues
MEETQGSRTYQILNEIFNAITHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHSLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALHPVGFWLLVAGGVVYSVGALVYHFKFPFAHVVWHLFVLLAAILMFFSVYLYVG

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI154759277, Length=206, Percent_Identity=28.6407766990291, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1789266, Length=213, Percent_Identity=38.4976525821596, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71996356, Length=219, Percent_Identity=31.0502283105023, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23927; Mature: 23927

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETQGSRTYQILNEIFNAITHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILFLCSTLAHSLHFTKAVKVFRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPLWNALHPVGFWLLVAGGVVYS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALVYHFKFPFAHVVWHLFVLLAAILMFFSVYLYVG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEETQGSRTYQILNEIFNAITHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILFLCSTLAHSLHFTKAVKVFRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPLWNALHPVGFWLLVAGGVVYS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALVYHFKFPFAHVVWHLFVLLAAILMFFSVYLYVG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]