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The map label for this gene is groES [H]

Identifier: 125623277

GI number: 125623277

Start: 403761

End: 404045

Strand: Direct

Name: groES [H]

Synonym: llmg_0410

Alternate gene names: 125623277

Gene position: 403761-404045 (Clockwise)

Preceding gene: 125623276

Following gene: 125623278

Centisome position: 15.96

GC content: 39.3

Gene sequence:

>285_bases
ATGTTGAAACCTTTAGAGAATCGCGTAGTTTTACGTGTAAAAGAAGAAGAGGAAAAATCTATGGGCGGAATCGTATTAAC
GAGCGCTTCCCAAGAAAAACCTCAAACAGCTGAAGTTATTGCTGTCGGTGAAGGGAAAACAACTAATCATGGGACACTGA
TTTCTCCACTCGTAAAAGTTGGAGATACAGTAATTTTTGAGAAATTTGCCGGAACGACTGTCAAAATGGACGGTGAAGAA
TTCTTGATTCTCAAAGACTCAGACCTTCTTGCAATTGTAGAGTAA

Upstream 100 bases:

>100_bases
AATGTTTTCTCTTGACTAAATCTGACCATTGAGATAAAATAAGAATATGTTAGCACTCAACTATTAAGAGTGCTAAAAAT
AAAAAATGGAGGAAAGTATA

Downstream 100 bases:

>100_bases
AAATATAAAAGCAATCAATTTTTGATTGTCTTTTGTCTATCTTAAAATCTATTAATTAAAAATATATTCTTAAAAAAGGA
GCTAAAATGTCAAAAGAAAT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVIAVGEGKTTNHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE

Sequences:

>Translated_94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVIAVGEGKTTNHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE
>Mature_94_residues
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVIAVGEGKTTNHGTLISPLVKVGDTVIFEKFAGTTVKMDGEE
FLILKDSDLLAIVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=49.4736842105263, Blast_Score=79, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=37.3626373626374, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=37.0786516853933, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10199; Mature: 10199

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVIAVGEGKTTNHGTLISPLVKV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
GDTVIFEKFAGTTVKMDGEEFLILKDSDLLAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MLKPLENRVVLRVKEEEEKSMGGIVLTSASQEKPQTAEVIAVGEGKTTNHGTLISPLVKV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHC
GDTVIFEKFAGTTVKMDGEEFLILKDSDLLAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486277; 11337471 [H]