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The map label for this gene is tpx [H]

Identifier: 125623189

GI number: 125623189

Start: 303499

End: 303981

Strand: Direct

Name: tpx [H]

Synonym: llmg_0318

Alternate gene names: 125623189

Gene position: 303499-303981 (Clockwise)

Preceding gene: 125623188

Following gene: 125623190

Centisome position: 12.0

GC content: 35.4

Gene sequence:

>483_bases
ATGACAATGAATATCACATCTCATGGTGAAAAAATAGCAACAATAAATCCGACAACAAGTGGTGATGCACCTGATTTTGA
ACTGACAGATTTAAAAGGAAATAAAATTAAATTATCAAAACTTGAAAAGCCTGTTTTGATTAGTGTATTCCCAGACATCA
ATACTAGAGTTTGTTCACTTCAAACCAAACATTTTAATCTTGAAGCAGCAAAGCATTCAGAAATTGACTTTTTGAGTATT
TCAAATAATACAGCAGATGAGCAAAAAAATTGGTGTGCAGCCGAGGGAGTTGACATGACAATTCTTGCTGATGATGGAAC
TTTTGGACAAGCTTATGGTCTTGTTTTAAATGATGGACCACTCAAGGGCCGTCTTGCTCGTAGTGTTTTTGTTGTAAAAG
AGGGGCAAATCGTCTATAGTGAAATATTAGCGGAGCTTTCGGATGAGCCTAATTACGAAAAAGCCTTAGAAGCAACTAAA
TAA

Upstream 100 bases:

>100_bases
TAGAAAGTCCCTACCTGACAGCGAAAGATGAGCAATAAGAGCCAGATGAGAGGATATTCTGTGATAGAATGAAAATATAA
CTATTAATAAAGGAGCATTA

Downstream 100 bases:

>100_bases
TTAATGACAAAAAATTGAGGATATTGATAAGAGTGAATATCCTCTGTAAAAGCTGTCAGTAGACAGTTTTTTTAATAAGT
TAAAGAAAAGATGTAATTTT

Product: thiol peroxidase

Products: oxidized thioredoxin; H2O [C]

Alternate protein names: Superoxide-inducible protein 8; SOI8 [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTMNITSHGEKIATINPTTSGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSI
SNNTADEQKNWCAAEGVDMTILADDGTFGQAYGLVLNDGPLKGRLARSVFVVKEGQIVYSEILAELSDEPNYEKALEATK

Sequences:

>Translated_160_residues
MTMNITSHGEKIATINPTTSGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSI
SNNTADEQKNWCAAEGVDMTILADDGTFGQAYGLVLNDGPLKGRLARSVFVVKEGQIVYSEILAELSDEPNYEKALEATK
>Mature_159_residues
TMNITSHGEKIATINPTTSGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSLQTKHFNLEAAKHSEIDFLSIS
NNTADEQKNWCAAEGVDMTILADDGTFGQAYGLVLNDGPLKGRLARSVFVVKEGQIVYSEILAELSDEPNYEKALEATK

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1787584, Length=167, Percent_Identity=31.1377245508982, Blast_Score=84, Evalue=3e-18,

Paralogues:

None

Copy number: 2480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: 1.11.1.- [C]

Molecular weight: Translated: 17517; Mature: 17386

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNITSHGEKIATINPTTSGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSL
CEEEECCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCEEEEE
QTKHFNLEAAKHSEIDFLSISNNTADEQKNWCAAEGVDMTILADDGTFGQAYGLVLNDGP
EECEEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEEEECCC
LKGRLARSVFVVKEGQIVYSEILAELSDEPNYEKALEATK
CCCEEEEEEEEEECCCEEHHHHHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure 
TMNITSHGEKIATINPTTSGDAPDFELTDLKGNKIKLSKLEKPVLISVFPDINTRVCSL
EEEECCCCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCCCCCEEEEE
QTKHFNLEAAKHSEIDFLSISNNTADEQKNWCAAEGVDMTILADDGTFGQAYGLVLNDGP
EECEEEEEECCCCCEEEEEECCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEEEEECCC
LKGRLARSVFVVKEGQIVYSEILAELSDEPNYEKALEATK
CCCEEEEEEEEEECCCEEHHHHHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced thioredoxin; H2O2 [C]

Specific reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 9298659 [H]