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The map label for this gene is gcp [H]

Identifier: 125623180

GI number: 125623180

Start: 295382

End: 296407

Strand: Direct

Name: gcp [H]

Synonym: llmg_0309

Alternate gene names: 125623180

Gene position: 295382-296407 (Clockwise)

Preceding gene: 125623179

Following gene: 125623181

Centisome position: 11.68

GC content: 40.64

Gene sequence:

>1026_bases
ATGAAAGATAATTATATATTAGCCTTTGAAACTTCATGTGATGAAACTTCAGTGGCGATTTTAAAAAATGGAAGTGAATT
ATTATGTAATATCATTGCCAGTCAAATCAATAGTCATAAACGTTTTGGTGGGGTTGTGCCCGAAATTGCCAGCCGTCATC
ATGTAGAACAAATTACCGTTTGTATTGAAGCAGCGCTTGAAGAAGCGGAAATTTCAGCTGACCAACTGACAGCCGTTGCG
GTGACAGAAGGCCCAGGACTAAACGGTGCTTTATTAGTTGGAATCATGGCTGCAAAAACTTTTGCTTGGGCCAACCATCT
GCCTTTGATTCCTGTCAATCATATGGCAGGGCATTTGATGGCGGCGAGTTTAGTCGATACCATCGAATATCCGGCCATGG
CTCTTTTGGTTTCAGGTGGACACTCTGAATTGGTTTACGTTGAAAAAGAAGGAAGCTATAAAAAAGTTGGCGAAACACGG
GATGATGCGGCCGGTGAAGCTTATGATAAAGTTGGTCGGGTGATGGGATTAACTTATCCTAGTGGAAAAGTCATTGATGA
ACTGGCCCATAAAGGTCAGGACACTTACAATTTCCCACGAGCTATGATGAACACACATGAAGTAGAATTTAGCTTTTCCG
GATTGAAATCAGCCTTTATCAATCTTGTACATAATGAAAATCAAAAAGGCAATGATGTGATTGCCAATGACTTAGAAAAT
CTGGCAGCTTCTTTTCAAGTAGCAGTTGTTGATGTACTGATGGCTAAAACTAAATTGGCTATGGAAAAATACCCTGTCAA
AACTTTAATTATTGGCGGTGGAGTATCAGCAAACCAGGGCCTACGTGAGCGTCTGTCAGCAGAAATTACTGACGAAAAAT
TAATCATTCCCCCTTTGCGCCTTTGTGGGGATAATGCCGGTATGATTGCAGCAGCAGCCTACATTGAATGGAAAAAAGGT
CTTGAAAATGTTCAAGCAGGATTAGACTTAAATGCTAAACCTAGCCTTGTTTTTGAAGATATGTAA

Upstream 100 bases:

>100_bases
GTTATGAAAAATTCGGTTTTGAAATTTATCATACAAGAAAAAATTACTATGACAAACCTCTTGAAGATGCTTTGTTAATG
AGAAAAGAGCAATTTTAAAA

Downstream 100 bases:

>100_bases
TAAGGAGAATTTTAATGATGAAATTAATCGGAAAACTTCAGAATGGTATGACCTTTACTGAAGAATTTGATGGGATCAAC
GATTTTTTAGCCCTTCAACA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITVCIEAALEEAEISADQLTAVA
VTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLMAASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETR
DDAAGEAYDKVGRVMGLTYPSGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLEN
LAASFQVAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLRLCGDNAGMIAAAAYIEWKKG
LENVQAGLDLNAKPSLVFEDM

Sequences:

>Translated_341_residues
MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITVCIEAALEEAEISADQLTAVA
VTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLMAASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETR
DDAAGEAYDKVGRVMGLTYPSGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLEN
LAASFQVAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLRLCGDNAGMIAAAAYIEWKKG
LENVQAGLDLNAKPSLVFEDM
>Mature_341_residues
MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITVCIEAALEEAEISADQLTAVA
VTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLMAASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETR
DDAAGEAYDKVGRVMGLTYPSGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLEN
LAASFQVAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLRLCGDNAGMIAAAAYIEWKKG
LENVQAGLDLNAKPSLVFEDM

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=346, Percent_Identity=30.9248554913295, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI8923380, Length=319, Percent_Identity=28.5266457680251, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=42.042042042042, Blast_Score=253, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=34.7692307692308, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=324, Percent_Identity=30.8641975308642, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320099, Length=361, Percent_Identity=30.1939058171745, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=354, Percent_Identity=28.8135593220339, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129063, Length=335, Percent_Identity=34.0298507462687, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357207, Length=326, Percent_Identity=30.0613496932515, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36710; Mature: 36710

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITV
CCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
CIEAALEEAEISADQLTAVAVTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLM
HHHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
AASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETRDDAAGEAYDKVGRVMGLTYP
HHHHHHHHHCCEEEEEEECCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHEECCC
SGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLEN
CCHHHHHHHHCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAASFQVAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLR
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEECCCHH
LCGDNAGMIAAAAYIEWKKGLENVQAGLDLNAKPSLVFEDM
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MKDNYILAFETSCDETSVAILKNGSELLCNIIASQINSHKRFGGVVPEIASRHHVEQITV
CCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
CIEAALEEAEISADQLTAVAVTEGPGLNGALLVGIMAAKTFAWANHLPLIPVNHMAGHLM
HHHHHHHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
AASLVDTIEYPAMALLVSGGHSELVYVEKEGSYKKVGETRDDAAGEAYDKVGRVMGLTYP
HHHHHHHHHCCEEEEEEECCCCEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHEECCC
SGKVIDELAHKGQDTYNFPRAMMNTHEVEFSFSGLKSAFINLVHNENQKGNDVIANDLEN
CCHHHHHHHHCCCCCCCCCHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAASFQVAVVDVLMAKTKLAMEKYPVKTLIIGGGVSANQGLRERLSAEITDEKLIIPPLR
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCCEEECCCHH
LCGDNAGMIAAAAYIEWKKGLENVQAGLDLNAKPSLVFEDM
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]