| Definition | Lactococcus lactis subsp. cremoris MG1363, complete genome. |
|---|---|
| Accession | NC_009004 |
| Length | 2,529,478 |
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The map label for this gene is yqhE [C]
Identifier: 125623149
GI number: 125623149
Start: 263015
End: 263860
Strand: Direct
Name: yqhE [C]
Synonym: llmg_0276
Alternate gene names: 125623149
Gene position: 263015-263860 (Clockwise)
Preceding gene: 125623148
Following gene: 125623150
Centisome position: 10.4
GC content: 38.06
Gene sequence:
>846_bases ATGACATTAACAGACACTTACACACTAAACAATGGCATTAAAATCCCAAAAGTTGGTTTTGGGACTTGGCAATCAGCAAG TGGAGAAGAAGCTTATAATGCAGTAAAAGCTGCCCTTGAAGCAGGCTATCGTCATATCGATACAGCGGCTGCTTACAAAA ATGAAGAATCTGTTGGTAAAGCAATTGCTGACTCAGGAATTCCACGTGAAGAACTTTTCATTACTACTAAACTTTGGGGC GTAGGAACGACAGAAGATGCAGCAAAAGCATTGGACGAGTCATTGGAAAAATTGGGGCTTGATTATGTCGATTTATATCT CATTCATTGGCCAAATCCAAAGGCTTTTCGTCCTGACTTTGAAAAACGCAATCTCGCTGTTTGGAAAGCAATGGAAGCAG GATTAAAAGCTGGGAAAACTCGTGCGATTGGTGTTTCAAACTTCCATCCACGTCATTTGAAACCTTTGTTGAAATTTGCT GAAATCAAACCAGCAGTTAACCAAATCATGGTCAATCCAAGTGATCAACAAGAAGAAATTGTAAGTTTTAATGTGGACAA TAATATCTTGACTGAGGCTTATAGCCCGCTTGGAACTGGTAAAATCTTTGAAGTTGCAGAACTTGCTGATTTGGCAAATA AATATAATAAAACAATTGCCCAAGTGGTACTTCGTTGGTCACTTCATAAAGGATACCTCCCACTTCCTAAATCAGTAACC CCTGCTCGAATTAAAGAAAATGCAGAAATCTTTGATTTTGATTTAAGTATTGAAGATATTGCTTTTATTGACAGTCTTCA CGGTAAAGCTGGATTGGCTAAAAATCCTGATGAAGTTGATTTCTAA
Upstream 100 bases:
>100_bases GTTAGAACTTTGGTTTCCCATTGAAAGAATTTAAGAAGCAAAAAAGAGTTTTGATTGGTGACGAACTCATGTATTTTTAA AATTACTAAGGAGAAAAAAT
Downstream 100 bases:
>100_bases AGAATAATTATGAAATATTTTACTGACAGATTGTTTACCTCTCTTACAAGACAGCAGAGAATTTGGTCAGTAAATTAAAA AAGGTCTGTCAGTAGATTTT
Product: aldo/keto reductase family oxidoreductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 281; Mature: 280
Protein sequence:
>281_residues MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAAYKNEESVGKAIADSGIPREELFITTKLWG VGTTEDAAKALDESLEKLGLDYVDLYLIHWPNPKAFRPDFEKRNLAVWKAMEAGLKAGKTRAIGVSNFHPRHLKPLLKFA EIKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVAELADLANKYNKTIAQVVLRWSLHKGYLPLPKSVT PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF
Sequences:
>Translated_281_residues MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAAYKNEESVGKAIADSGIPREELFITTKLWG VGTTEDAAKALDESLEKLGLDYVDLYLIHWPNPKAFRPDFEKRNLAVWKAMEAGLKAGKTRAIGVSNFHPRHLKPLLKFA EIKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVAELADLANKYNKTIAQVVLRWSLHKGYLPLPKSVT PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF >Mature_280_residues TLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAAYKNEESVGKAIADSGIPREELFITTKLWGV GTTEDAAKALDESLEKLGLDYVDLYLIHWPNPKAFRPDFEKRNLAVWKAMEAGLKAGKTRAIGVSNFHPRHLKPLLKFAE IKPAVNQIMVNPSDQQEEIVSFNVDNNILTEAYSPLGTGKIFEVAELADLANKYNKTIAQVVLRWSLHKGYLPLPKSVTP ARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=287, Percent_Identity=37.2822299651568, Blast_Score=190, Evalue=1e-48, Organism=Homo sapiens, GI5174391, Length=287, Percent_Identity=37.2822299651568, Blast_Score=190, Evalue=1e-48, Organism=Homo sapiens, GI223468663, Length=293, Percent_Identity=38.5665529010239, Blast_Score=180, Evalue=1e-45, Organism=Homo sapiens, GI5174695, Length=297, Percent_Identity=38.047138047138, Blast_Score=177, Evalue=1e-44, Organism=Homo sapiens, GI310109920, Length=296, Percent_Identity=38.1756756756757, Blast_Score=174, Evalue=9e-44, Organism=Homo sapiens, GI45446745, Length=296, Percent_Identity=38.1756756756757, Blast_Score=174, Evalue=9e-44, Organism=Homo sapiens, GI4503285, Length=296, Percent_Identity=38.1756756756757, Blast_Score=174, Evalue=9e-44, Organism=Homo sapiens, GI24497585, Length=296, Percent_Identity=37.8378378378378, Blast_Score=174, Evalue=1e-43, Organism=Homo sapiens, GI5453543, Length=296, Percent_Identity=37.8378378378378, Blast_Score=173, Evalue=2e-43, Organism=Homo sapiens, GI310109922, Length=282, Percent_Identity=38.6524822695035, Blast_Score=172, Evalue=3e-43, Organism=Homo sapiens, GI4502049, Length=291, Percent_Identity=41.5807560137457, Blast_Score=171, Evalue=5e-43, Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=37.2881355932203, Blast_Score=170, Evalue=1e-42, Organism=Homo sapiens, GI300116273, Length=280, Percent_Identity=37.5, Blast_Score=162, Evalue=2e-40, Organism=Homo sapiens, GI93277124, Length=309, Percent_Identity=33.9805825242718, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI291291012, Length=266, Percent_Identity=36.8421052631579, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI300116271, Length=278, Percent_Identity=33.4532374100719, Blast_Score=134, Evalue=7e-32, Organism=Homo sapiens, GI310109926, Length=110, Percent_Identity=49.0909090909091, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI207028673, Length=110, Percent_Identity=49.0909090909091, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI310109924, Length=153, Percent_Identity=34.640522875817, Blast_Score=85, Evalue=6e-17, Organism=Escherichia coli, GI87082198, Length=272, Percent_Identity=44.8529411764706, Blast_Score=227, Evalue=6e-61, Organism=Escherichia coli, GI1786400, Length=259, Percent_Identity=38.6100386100386, Blast_Score=155, Evalue=3e-39, Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=30.5147058823529, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=25.4716981132075, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI48994888, Length=259, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI87081735, Length=300, Percent_Identity=25, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71998625, Length=265, Percent_Identity=37.3584905660377, Blast_Score=190, Evalue=8e-49, Organism=Caenorhabditis elegans, GI17537077, Length=295, Percent_Identity=40.6779661016949, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17537075, Length=295, Percent_Identity=40.6779661016949, Blast_Score=184, Evalue=6e-47, Organism=Caenorhabditis elegans, GI17564128, Length=301, Percent_Identity=37.2093023255814, Blast_Score=179, Evalue=1e-45, Organism=Caenorhabditis elegans, GI17550248, Length=292, Percent_Identity=40.7534246575342, Blast_Score=171, Evalue=5e-43, Organism=Caenorhabditis elegans, GI17566692, Length=289, Percent_Identity=35.9861591695502, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17561298, Length=270, Percent_Identity=36.6666666666667, Blast_Score=165, Evalue=2e-41, Organism=Caenorhabditis elegans, GI17537079, Length=302, Percent_Identity=34.1059602649007, Blast_Score=161, Evalue=4e-40, Organism=Caenorhabditis elegans, GI17538386, Length=281, Percent_Identity=34.1637010676157, Blast_Score=155, Evalue=1e-38, Organism=Caenorhabditis elegans, GI17562292, Length=254, Percent_Identity=35.0393700787402, Blast_Score=154, Evalue=5e-38, Organism=Caenorhabditis elegans, GI17552492, Length=265, Percent_Identity=34.7169811320755, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17561300, Length=251, Percent_Identity=33.8645418326693, Blast_Score=133, Evalue=8e-32, Organism=Caenorhabditis elegans, GI17550246, Length=75, Percent_Identity=52, Blast_Score=72, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324694, Length=292, Percent_Identity=43.8356164383562, Blast_Score=222, Evalue=6e-59, Organism=Saccharomyces cerevisiae, GI6320576, Length=288, Percent_Identity=43.4027777777778, Blast_Score=219, Evalue=4e-58, Organism=Saccharomyces cerevisiae, GI6322556, Length=271, Percent_Identity=37.6383763837638, Blast_Score=170, Evalue=2e-43, Organism=Saccharomyces cerevisiae, GI6319625, Length=274, Percent_Identity=38.6861313868613, Blast_Score=161, Evalue=1e-40, Organism=Saccharomyces cerevisiae, GI6320079, Length=297, Percent_Identity=37.7104377104377, Blast_Score=155, Evalue=5e-39, Organism=Saccharomyces cerevisiae, GI6321896, Length=307, Percent_Identity=32.2475570032573, Blast_Score=137, Evalue=2e-33, Organism=Drosophila melanogaster, GI24644950, Length=301, Percent_Identity=41.8604651162791, Blast_Score=206, Evalue=1e-53, Organism=Drosophila melanogaster, GI24657054, Length=284, Percent_Identity=42.9577464788732, Blast_Score=205, Evalue=3e-53, Organism=Drosophila melanogaster, GI221378297, Length=321, Percent_Identity=39.5638629283489, Blast_Score=198, Evalue=4e-51, Organism=Drosophila melanogaster, GI21356425, Length=282, Percent_Identity=40.4255319148936, Blast_Score=195, Evalue=3e-50, Organism=Drosophila melanogaster, GI24663317, Length=294, Percent_Identity=39.4557823129252, Blast_Score=194, Evalue=7e-50, Organism=Drosophila melanogaster, GI20129731, Length=288, Percent_Identity=39.5833333333333, Blast_Score=192, Evalue=2e-49, Organism=Drosophila melanogaster, GI24662789, Length=293, Percent_Identity=36.1774744027304, Blast_Score=176, Evalue=2e-44, Organism=Drosophila melanogaster, GI45553081, Length=286, Percent_Identity=38.8111888111888, Blast_Score=172, Evalue=2e-43, Organism=Drosophila melanogaster, GI24662781, Length=275, Percent_Identity=38.9090909090909, Blast_Score=156, Evalue=2e-38, Organism=Drosophila melanogaster, GI24662785, Length=273, Percent_Identity=38.4615384615385, Blast_Score=150, Evalue=1e-36, Organism=Drosophila melanogaster, GI281366140, Length=244, Percent_Identity=37.7049180327869, Blast_Score=148, Evalue=4e-36,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 31091; Mature: 30959
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 0.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAAYKNEESVGK CCCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHH AIADSGIPREELFITTKLWGVGTTEDAAKALDESLEKLGLDYVDLYLIHWPNPKAFRPDF HHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCH EKRNLAVWKAMEAGLKAGKTRAIGVSNFHPRHLKPLLKFAEIKPAVNQIMVNPSDQQEEI HHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCE VSFNVDNNILTEAYSPLGTGKIFEVAELADLANKYNKTIAQVVLRWSLHKGYLPLPKSVT EEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure TLTDTYTLNNGIKIPKVGFGTWQSASGEEAYNAVKAALEAGYRHIDTAAAYKNEESVGK CCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHH AIADSGIPREELFITTKLWGVGTTEDAAKALDESLEKLGLDYVDLYLIHWPNPKAFRPDF HHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCH EKRNLAVWKAMEAGLKAGKTRAIGVSNFHPRHLKPLLKFAEIKPAVNQIMVNPSDQQEEI HHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCE VSFNVDNNILTEAYSPLGTGKIFEVAELADLANKYNKTIAQVVLRWSLHKGYLPLPKSVT EEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PARIKENAEIFDFDLSIEDIAFIDSLHGKAGLAKNPDEVDF HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA