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The map label for this gene is yusP [H]

Identifier: 125623125

GI number: 125623125

Start: 236277

End: 237737

Strand: Reverse

Name: yusP [H]

Synonym: llmg_0249

Alternate gene names: 125623125

Gene position: 237737-236277 (Counterclockwise)

Preceding gene: 125623134

Following gene: 125623123

Centisome position: 9.4

GC content: 40.45

Gene sequence:

>1461_bases
TTGAATAAAATACAAGAAAAACGCTCCATTCGAGCCTTTATGCTTTCCAATGTCATGGCAGGTTTGGAAGGCTCAATTGT
GGCTACTGCTCTGCCAGCAATGATGGCAGAATTACACGGCATCAAGTTGATGAGTTGGGTTGTAACTATTTATATGCTCC
TCATGGCGGTTTCTTCTCCCATTTGGACAAAACTGGCCGAACGTTTTGGTTATAAACAAATGTTTGTGCTCGGCACACTT
TTATTTACTATAGGTTCTCTCGGCGAAGGATTAGCTATTAATATGTTGATGGTCATTGTCGCCCGCGCCCTCATGGGACT
TGGTGCTGGTGTGATGATTCAACTTCCTTTTGTCATCTATGGAATGATGTATCAGGCTGATGAGCGGAGACGCGTGATTG
GAAATACTGTCGCTGCTTATTCATTTTCAACCATTGCCGGACCAATTGTCGGAGGTTTGATTGTAAACTTACTTGACTGG
CGCTGGGTCTTTTTCATCAATATTCCGATTGGGATTTACATGGCTTTTATTGTTTGGAAAAATTTCGATCTTAAAACTGA
CCATACTAAAAAATCAATTGATTTTGCTGGTTCTGCTTCTCTATCCATTGCCGTCATTGCCATTATGCTTCTTTTTCAAA
TGATGGGGAATGCCGTCATTAATCTTCCATTATTGATTGCTCTGTTGTTTATCAGTTTGCTCTTTTTCACTGGATTTTAT
TTTGCTGAAAAAAGAGCGGTTGATCCAATTGTTCCGCTTGAACTTTTCAAAAATCCGTCTTTCATTGCCAAAAATATCAT
GTTTTTCATGCAATATGGTTTCTTTGGTTTTTATACAAACTATCTGCCCACTTGGGGACAAGGGGTCATGGGCGCAACGG
CTTTAGTCGGTGGAATGGTTTTGATTCCGTCAGCAATTATGCTAGTTATCGGAACGAGAAATGTCAATCATCTCATTCAA
AAAGTCGGTGAAAAAAGAACGATTTATATCGGTTTTGCTATCATGGTTTTAGGTGCACTTTTCTTATTTAGTTTGCCTGA
ACATGCCTCAATTCTTATGCTCTTTGTCGCGACAGCAATTCTTGGCACCGCCTTTGGGATTGTCAACATTACCTTGCAGG
TTGCAGTTCAAGAAAGTGTCGCTAAGCATTTGATTGGTGCAGCGACTGCCGTTAATGCTTTACTAAGAACAATGGGAACA
ACACTTGTCTTATCTGGCTTATCAATCGCTCTCAACCGTACATTTACTGACTCAACTGCACATAATCCAAAACTTACGAC
GACACTTCTTAATCAAATTTCTGATGCTCAAGCTTTAAAAAATATTCCCACTGCACTCGTTGCCCCTTTGCGTCACACCC
TATTTAATGGTATGCACTTGCTTGCGCTTATCTCCGGCTTACTTCTTTTCATTGCGCTTTTTGTCAATTGGCTCGACCCT
TGGAAAAAAGGACTAGAATAA

Upstream 100 bases:

>100_bases
TGAGTTAGAGTAACTCTAACTTGCTATAATATAGCATGTTGATTTCAAAGTGTCAACCACCGCATTTTGAATCTTTATTT
TAATATAGAAAAGAGAAAAA

Downstream 100 bases:

>100_bases
AACAAAAAAATGCTGACAACTCTGTCAGTAGTTTTTATTTTACTGACAAGACTTCTGTCATAGGATAGCCGTTTGCGCTT
TAGCACATTTACGGATATGC

Product: putative transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFGYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVNLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLLFQMMGNAVINLPLLIALLFISLLFFTGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKRTIYIGFAIMVLGALFLFSLPEHASILMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTDSTAHNPKLTTTLLNQISDAQALKNIPTALVAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE

Sequences:

>Translated_486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFGYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVNLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLLFQMMGNAVINLPLLIALLFISLLFFTGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKRTIYIGFAIMVLGALFLFSLPEHASILMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTDSTAHNPKLTTTLLNQISDAQALKNIPTALVAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE
>Mature_486_residues
MNKIQEKRSIRAFMLSNVMAGLEGSIVATALPAMMAELHGIKLMSWVVTIYMLLMAVSSPIWTKLAERFGYKQMFVLGTL
LFTIGSLGEGLAINMLMVIVARALMGLGAGVMIQLPFVIYGMMYQADERRRVIGNTVAAYSFSTIAGPIVGGLIVNLLDW
RWVFFINIPIGIYMAFIVWKNFDLKTDHTKKSIDFAGSASLSIAVIAIMLLFQMMGNAVINLPLLIALLFISLLFFTGFY
FAEKRAVDPIVPLELFKNPSFIAKNIMFFMQYGFFGFYTNYLPTWGQGVMGATALVGGMVLIPSAIMLVIGTRNVNHLIQ
KVGEKRTIYIGFAIMVLGALFLFSLPEHASILMLFVATAILGTAFGIVNITLQVAVQESVAKHLIGAATAVNALLRTMGT
TLVLSGLSIALNRTFTDSTAHNPKLTTTLLNQISDAQALKNIPTALVAPLRHTLFNGMHLLALISGLLLFIALFVNWLDP
WKKGLE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=369, Percent_Identity=26.2872628726287, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081983, Length=423, Percent_Identity=22.9314420803783, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789042, Length=438, Percent_Identity=23.972602739726, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788710, Length=319, Percent_Identity=25.705329153605, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788392, Length=357, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322958, Length=429, Percent_Identity=26.5734265734266, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321663, Length=146, Percent_Identity=30.1369863013699, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325455, Length=153, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323735, Length=311, Percent_Identity=23.1511254019293, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53266; Mature: 53266

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCC
>Mature Secondary Structure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HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]