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The map label for this gene is hflX [H]

Identifier: 125623110

GI number: 125623110

Start: 224009

End: 225253

Strand: Direct

Name: hflX [H]

Synonym: llmg_0233

Alternate gene names: 125623110

Gene position: 224009-225253 (Clockwise)

Preceding gene: 125623109

Following gene: 125623112

Centisome position: 8.86

GC content: 38.47

Gene sequence:

>1245_bases
TTGATAGATTTAGAAGAAAAACAAGAAAGAGTACTCCTTGCGGGAGTAGAAACAGCCCAAAATTTTCAGGCTTTTGAGTC
ATCAATGGTTGAACTGGCTGAATTGACAAAAACGGCTGGCGGATTGGTCATTGACCAATTTACTCAAAAAAGAGAACGTC
CAGATAGTCGGACAATGATTGGTTCTGGAAAATTGGAACAAATGCGTTGGGCGATTGAAGTGGGCGAAATTGATACGGTT
ATTTTTAATGACCGTCTATCCCCAAGACAAAATGTCAATTTGGAAGAAGCTTTGGGCGTCAAAGTCATTGATAGAATGCA
ATTGATTTTGGATATTTTTGCCATGCGGGCTCGCTCACATGAAGGAATGCTTCAAGTGGAAGAAGCCCAGCTCAATTATC
TTTTGCCGCGTTTGGTCGGGCAAGGAATTATGCTCAGCCGTCAAGGTGGGGGAATTGGTTCTAAAGGACCAGGTGAAACC
AAGCTTGAAACAGATCGACGTTATATTCGCACTCGAATTGAAAATATTGATAAAGCCCTCAAAAAAGTTGAAAAAACAAG
GGAAAATATCCGCCAAAAACGCTCAAAATCAGGAATTTTTCGGATTGGCTTAATTGGTTACACCAATGCCGGAAAATCCA
GCATTATGAATGCTTTAATTGGTCTTGATAAAGAACAATATGAGCAAAATGAACTTTTTGCGACATTGGACGCCACAACA
AAAGCCGTTCAATTGGTTGAAGATTTTACGGTGTCACTGACAGATACTGTCGGTTTTATCCAAAATCTGCCAACAGAGCT
GATTAAAGCTTTTAAATCAACCTTAGAAGAATCTGCAAATGTTGATTTACTGATTCATGTCATTGATGCCAGCAATCCTC
ATCATGAAATTCATGAACAAACGGTCTTGAAAATCATGGAAGATTTGAAGCTTACCAATATTCCTGTGCTGAATGTTTAT
AATAAAATGGATATTGCCCCAAGTGACTTCTTGCCAACTTTGTCGACAAGTTTACAACTCTCAATTAAATCTGAGAATGG
TGTTCAATGGCTGAAAACAGCAATTTTGGAAAAATTGCATGAGCTTTTTGAAGCTTTTGAGATAGAATTACCTTATGAAA
AAGCTTATCAGTTGCCTGAATTAAGAAAGAGTGCCTTGGTTCAATCGGTAGTTGAAGGCGAAAATGCTTATCAGATTAAG
GGATTGATTGCGCCTGAATTGAGTTGGAAATTGAATGAGTTTTAG

Upstream 100 bases:

>100_bases
ATTGTGACAAATGAATAAATACAAAAATAGAGTTTAGTTTTATAATACTTTTAGTCTAAACTCAGCTGACAAAAATAAAA
AGGAAAATTTTACTAAAAAT

Downstream 100 bases:

>100_bases
AAATGACCAATATGAATAATTTGCTAAAGATTTGGTTGTCAGACTTAAAATATTTATTAATTTTTCAAAATCAAAAATAA
AACAGAGAATCTAAGGCATG

Product: GTP-binding protein hflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIDLEEKQERVLLAGVETAQNFQAFESSMVELAELTKTAGGLVIDQFTQKRERPDSRTMIGSGKLEQMRWAIEVGEIDTV
IFNDRLSPRQNVNLEEALGVKVIDRMQLILDIFAMRARSHEGMLQVEEAQLNYLLPRLVGQGIMLSRQGGGIGSKGPGET
KLETDRRYIRTRIENIDKALKKVEKTRENIRQKRSKSGIFRIGLIGYTNAGKSSIMNALIGLDKEQYEQNELFATLDATT
KAVQLVEDFTVSLTDTVGFIQNLPTELIKAFKSTLEESANVDLLIHVIDASNPHHEIHEQTVLKIMEDLKLTNIPVLNVY
NKMDIAPSDFLPTLSTSLQLSIKSENGVQWLKTAILEKLHELFEAFEIELPYEKAYQLPELRKSALVQSVVEGENAYQIK
GLIAPELSWKLNEF

Sequences:

>Translated_414_residues
MIDLEEKQERVLLAGVETAQNFQAFESSMVELAELTKTAGGLVIDQFTQKRERPDSRTMIGSGKLEQMRWAIEVGEIDTV
IFNDRLSPRQNVNLEEALGVKVIDRMQLILDIFAMRARSHEGMLQVEEAQLNYLLPRLVGQGIMLSRQGGGIGSKGPGET
KLETDRRYIRTRIENIDKALKKVEKTRENIRQKRSKSGIFRIGLIGYTNAGKSSIMNALIGLDKEQYEQNELFATLDATT
KAVQLVEDFTVSLTDTVGFIQNLPTELIKAFKSTLEESANVDLLIHVIDASNPHHEIHEQTVLKIMEDLKLTNIPVLNVY
NKMDIAPSDFLPTLSTSLQLSIKSENGVQWLKTAILEKLHELFEAFEIELPYEKAYQLPELRKSALVQSVVEGENAYQIK
GLIAPELSWKLNEF
>Mature_414_residues
MIDLEEKQERVLLAGVETAQNFQAFESSMVELAELTKTAGGLVIDQFTQKRERPDSRTMIGSGKLEQMRWAIEVGEIDTV
IFNDRLSPRQNVNLEEALGVKVIDRMQLILDIFAMRARSHEGMLQVEEAQLNYLLPRLVGQGIMLSRQGGGIGSKGPGET
KLETDRRYIRTRIENIDKALKKVEKTRENIRQKRSKSGIFRIGLIGYTNAGKSSIMNALIGLDKEQYEQNELFATLDATT
KAVQLVEDFTVSLTDTVGFIQNLPTELIKAFKSTLEESANVDLLIHVIDASNPHHEIHEQTVLKIMEDLKLTNIPVLNVY
NKMDIAPSDFLPTLSTSLQLSIKSENGVQWLKTAILEKLHELFEAFEIELPYEKAYQLPELRKSALVQSVVEGENAYQIK
GLIAPELSWKLNEF

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=251, Percent_Identity=34.6613545816733, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310124269, Length=243, Percent_Identity=34.9794238683128, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310124267, Length=243, Percent_Identity=34.9794238683128, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310124171, Length=243, Percent_Identity=34.9794238683128, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310124169, Length=243, Percent_Identity=34.9794238683128, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI310133118, Length=251, Percent_Identity=34.6613545816733, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1790615, Length=404, Percent_Identity=37.8712871287129, Blast_Score=244, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17561038, Length=323, Percent_Identity=28.1733746130031, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24650079, Length=315, Percent_Identity=31.1111111111111, Blast_Score=121, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46756; Mature: 46756

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLEEKQERVLLAGVETAQNFQAFESSMVELAELTKTAGGLVIDQFTQKRERPDSRTMI
CCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEE
GSGKLEQMRWAIEVGEIDTVIFNDRLSPRQNVNLEEALGVKVIDRMQLILDIFAMRARSH
CCCCHHHHHHEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGMLQVEEAQLNYLLPRLVGQGIMLSRQGGGIGSKGPGETKLETDRRYIRTRIENIDKAL
CCCEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KKVEKTRENIRQKRSKSGIFRIGLIGYTNAGKSSIMNALIGLDKEQYEQNELFATLDATT
HHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHEEEEHHHHH
KAVQLVEDFTVSLTDTVGFIQNLPTELIKAFKSTLEESANVDLLIHVIDASNPHHEIHEQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
TVLKIMEDLKLTNIPVLNVYNKMDIAPSDFLPTLSTSLQLSIKSENGVQWLKTAILEKLH
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
ELFEAFEIELPYEKAYQLPELRKSALVQSVVEGENAYQIKGLIAPELSWKLNEF
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MIDLEEKQERVLLAGVETAQNFQAFESSMVELAELTKTAGGLVIDQFTQKRERPDSRTMI
CCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEE
GSGKLEQMRWAIEVGEIDTVIFNDRLSPRQNVNLEEALGVKVIDRMQLILDIFAMRARSH
CCCCHHHHHHEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGMLQVEEAQLNYLLPRLVGQGIMLSRQGGGIGSKGPGETKLETDRRYIRTRIENIDKAL
CCCEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KKVEKTRENIRQKRSKSGIFRIGLIGYTNAGKSSIMNALIGLDKEQYEQNELFATLDATT
HHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHEEEEHHHHH
KAVQLVEDFTVSLTDTVGFIQNLPTELIKAFKSTLEESANVDLLIHVIDASNPHHEIHEQ
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHH
TVLKIMEDLKLTNIPVLNVYNKMDIAPSDFLPTLSTSLQLSIKSENGVQWLKTAILEKLH
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
ELFEAFEIELPYEKAYQLPELRKSALVQSVVEGENAYQIKGLIAPELSWKLNEF
HHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]