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The map label for this gene is prmA [H]

Identifier: 125622989

GI number: 125622989

Start: 102785

End: 103738

Strand: Direct

Name: prmA [H]

Synonym: llmg_0110

Alternate gene names: 125622989

Gene position: 102785-103738 (Clockwise)

Preceding gene: 125622988

Following gene: 125622990

Centisome position: 4.06

GC content: 40.78

Gene sequence:

>954_bases
ATGAATAACTGGAACTCAATCACTATAAAAATCAGTCGTGAAGCCGAAGAAACTATTTCGGCTTTGCTGATAGAAGCAGG
TTCGGCGGGTGTTGAAATCAATGACAGTGCTGATTACCTCAATCACGAAGACCAATTTGGGGAAGTTTTACCCGAAATTG
AGCAATCTGAACTCGTTGAAATCACGGCTTATTATCCAGAAAATATGCCAATTGTGGAATTAAAAGCCGAAATTGAACAT
AAAATCGCCAATTTAGCTGATTATTTTTCACTGACAGGTTTGTCAGTAACAACAAATAATCTGTCAGAAACAAATTGGGC
AGAAGCTTGGAAAAAATATTTTGAACCGGCACGTATCACTCATGATTTAACGATTGTCCCAAGTTGGACGAAGGATTACC
TGGCGACAGGTTCTGAAAAATTGATTCGCCTTGATCCAGGAATGGCTTTTGGGACTGGGACACATCCAACGACAAAAATG
TCACTCTATGCTTTGGAGCAAGTTTTGCGCGGTGGTGAAACTCTGCTTGACGTCGGAACGGGTTCGGGAGTTCTGTCTGT
TGCAGCGACTTATCTTGGCGCGGCAGAAATTTTTGCTTACGATATTGATGAAGTGGCTGTGCGCGTGGCTTTAGAAAATA
TTGAACTCAACCCTGGTCATGAAAAAATTCATGTGTCAGCAAACAATCTTCTTGAAGGAATTGATAAAAAAGCGGACGTG
ATTGTGGCCAATATTTTAGCTGATATTCTTGTTTTAATGACGGACGATGCTTTCCGCTTGGTTAAAGAAGAAGGATATCT
CATTATGTCAGGAATTATTGCTGACAAAGCGGATATGGTCATTGCATCAGCAGAAAATGCTGGATTTTTCCTTGAAACAC
GCATGATTCAAGGCGAATGGAACTGTCTGATTTTCAAGAAAACGGAAAATCGGGAAGGGGTAATTGGAGGATAA

Upstream 100 bases:

>100_bases
GACAGATGAAGCCATCGAGCGAAATGTGGCACGGGCCATTGGTTTTTTGCTGGGAAAGAATCGGTTTGTTGGTAGGGATA
AACCATAGAAAGAAATAAAA

Downstream 100 bases:

>100_bases
AATTTCATTTAAATCATATTAGGACCTTGGAAATGAGTGCTTTATCTTTTAGCAAATGATAAAATAAAGTAAACAATTCA
TTGAAGTGAATTTTATGAAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNNWNSITIKISREAEETISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVEITAYYPENMPIVELKAEIEH
KIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRMIQGEWNCLIFKKTENREGVIGG

Sequences:

>Translated_317_residues
MNNWNSITIKISREAEETISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVEITAYYPENMPIVELKAEIEH
KIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRMIQGEWNCLIFKKTENREGVIGG
>Mature_317_residues
MNNWNSITIKISREAEETISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVEITAYYPENMPIVELKAEIEH
KIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARITHDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKM
SLYALEQVLRGGETLLDVGTGSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
IVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRMIQGEWNCLIFKKTENREGVIGG

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=259, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34819; Mature: 34819

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNWNSITIKISREAEETISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVE
CCCCEEEEEEEECCHHHHHHHHHEECCCCCEEECCCHHHCCCCHHHHHHCCCCCCCCEEE
ITAYYPENMPIVELKAEIEHKIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARIT
EEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKMSLYALEQVLRGGETLLDVGT
EEEEEECCCCHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
CCHHHHHHHHHHCHHHHEEECHHHHHEEEEEEEEEECCCCCEEEEEHHHHHHHCCCHHHH
IVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRMIQGEW
HHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
NCLIFKKTENREGVIGG
EEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNNWNSITIKISREAEETISALLIEAGSAGVEINDSADYLNHEDQFGEVLPEIEQSELVE
CCCCEEEEEEEECCHHHHHHHHHEECCCCCEEECCCHHHCCCCHHHHHHCCCCCCCCEEE
ITAYYPENMPIVELKAEIEHKIANLADYFSLTGLSVTTNNLSETNWAEAWKKYFEPARIT
EEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTKDYLATGSEKLIRLDPGMAFGTGTHPTTKMSLYALEQVLRGGETLLDVGT
EEEEEECCCCHHHHCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECC
GSGVLSVAATYLGAAEIFAYDIDEVAVRVALENIELNPGHEKIHVSANNLLEGIDKKADV
CCHHHHHHHHHHCHHHHEEECHHHHHEEEEEEEEEECCCCCEEEEEHHHHHHHCCCHHHH
IVANILADILVLMTDDAFRLVKEEGYLIMSGIIADKADMVIASAENAGFFLETRMIQGEW
HHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCC
NCLIFKKTENREGVIGG
EEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]