Click here to switch to the map view.

The map label for this gene is mtlR [H]

Identifier: 125622904

GI number: 125622904

Start: 28377

End: 30311

Strand: Direct

Name: mtlR [H]

Synonym: llmg_0023

Alternate gene names: 125622904

Gene position: 28377-30311 (Clockwise)

Preceding gene: 125622903

Following gene: 125622905

Centisome position: 1.12

GC content: 32.35

Gene sequence:

>1935_bases
ATGTTTTTAACAAGTCGTGAGCAAAAATTAATCCATACATTTTTGAAACGTGGAACGCTTACGATATCAGAAATGATGGA
AATAACAGGAACAAGTCGCAGAACCCTTTATCGCGATTTAAATAACTTACAAAAATCTTTACCAGAAGAGATAAGTTTAC
AAACTTCTGAGGAAGGATATTTTATAAAAGGAGATATAAAGCAACTCTCTCAAGCTCATGAACTAGTAGAATATACGATG
ACTGAGCGCTTGTATGGTGAGATACTTTTATTGATTGAAAATAGAGCATCCATTTTGTCATTGACGGATTATTTTGGTAT
TAGTCAGCCAACGGTCACGAATGATTTGAGACAATTAGAACAGACCTTAATTGAAAATGAAATTTCATTAATAAGGGAGC
GAGGCCTAAAGATTGAGGGATTAGAAGAGAATATTCGGTCAGTATTTGTGGCTGCAATATATAATTCTGCATCGCTTCAA
GAATTGATTAGTAATCAACTTTCAGACAATAAACTTTTAAGTATCTTGGACTTAGATAAATTTAAGCAAGCTTATGATGC
TTTTGAATCCCTAATCTTGCCAGAAGATATGACAGATAAAGTGAGAGTACTGATGGAACTCTTTCTTGTAACAACTCTAA
TCCGGATAGACGAGGGACATTTCATCACAAGTGAGAGTCTTAGTAGTCCAAGCAAAGGAGCGCTGAACTTTGTTAATAAA
TTACTGACAGCTCTGTCAGTAACAAAATTTGTTGTATCTGAGATTACTTATCTTGCTTCGGTCTATGAAATTTTATATTT
TGGATTTGGCCGAGAATTATTATTTATGGAAAAATTTGATACAGATTTCTCCTATAAAATTCGTCAGATTATTGATCGGG
TTTCCACAAAACTTGAGATTGAATTTGGAAAAGACGACCGATTATATGGTTTGCTTTATGCTCATCTCAAAGAATCAGAG
ATGTTACCCATTCTTTTTCCTAAAAAAGAAAATGATTTTATCAAAAAAATTAAGAAAGATAATCCAGAAATTTATAAAGC
CGTCAATGAATCATTGAAGCTGATTTTTGATAAAAATTTTTCAGAAATGGAAATCACTTTTGTAACCCTTCATTTTGTGT
CAACCTTGGAAAGAAGTGATCTTGTTTTACCATTACGCTCAGCACTCGTAAGTAATCGTGGACGGATTTCATGTGAATTT
GTCATGAGTAATTTAAGGAAAAATTTTCCATTCTTAAAAAAAATAGACCTCATTCAAAATTCTGTGAAAGTTGTCAAATC
CCAATATGATGTTATTTTTACTACTGAGAAGGAGTTTGATTATCTTTATATCAATCCAATGTTAGATCAAAAAAATCTGG
ATAATATTCGTCATCAATTAAGACATATTCAACAAAAATCGCGAACGCTAACTATTGATTCAAAAGAGCAAAGAAACTTT
TTAAATCTTAATGACTTATTTACGACTGGTAATGAAATTTTAAGCACTTTTGAAATTAAGACACTTTCAAACCAGCCAAA
GTTGAGCGATACTGTAAAACAAATCGCAAAAACTGTAAACGAAGATGATGGAGAATTAGCAGAACTAATAGAAGAAAGAT
TTCGGGAGACACATCTGGCAATTCCTGAAACTAATATTGCTCTTTTTCATGCAGTTCATTCATCGATTTCAAGTCCACTA
TTCAAGATTTATGAGCTAAGTCAGGAAATTGAGGGGATGGCAATGGATCATCAAATGATAAAAATTAATCGTGTTTTACT
ACTTTTGGCACCTCCAGAAGTACCAGAATATGTTTCATATTTACTCGGAAAACTTTCAAGCTCGATTATTGAAAATAAGC
TTTATACAAGAATATATGATTCCGGTAACTATGAAATTGTTAGTGAGTTGCTAAGGGAAATAATCATAGAAGCTGTTAAA
CAGTATGGTGATTAG

Upstream 100 bases:

>100_bases
CTCCAGAATACATCAATATGGTAAATCGAATGAACAAATAAAAAATCAATTGATTAGCTGATTAGTGAATAAGTAGAAAT
CAAAACAAAAAGGAATATTT

Downstream 100 bases:

>100_bases
GTTTACGGCGTGTGTAAACCTAGTAAACCAAGAAAGGTGAAGAAAAATGGAAATCCAAAAAGAGCTTATTAAAATCAATC
AAAATTTTTCAAATAAGGAA

Product: transcriptional regulator mtl operon mtlR

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MFLTSREQKLIHTFLKRGTLTISEMMEITGTSRRTLYRDLNNLQKSLPEEISLQTSEEGYFIKGDIKQLSQAHELVEYTM
TERLYGEILLLIENRASILSLTDYFGISQPTVTNDLRQLEQTLIENEISLIRERGLKIEGLEENIRSVFVAAIYNSASLQ
ELISNQLSDNKLLSILDLDKFKQAYDAFESLILPEDMTDKVRVLMELFLVTTLIRIDEGHFITSESLSSPSKGALNFVNK
LLTALSVTKFVVSEITYLASVYEILYFGFGRELLFMEKFDTDFSYKIRQIIDRVSTKLEIEFGKDDRLYGLLYAHLKESE
MLPILFPKKENDFIKKIKKDNPEIYKAVNESLKLIFDKNFSEMEITFVTLHFVSTLERSDLVLPLRSALVSNRGRISCEF
VMSNLRKNFPFLKKIDLIQNSVKVVKSQYDVIFTTEKEFDYLYINPMLDQKNLDNIRHQLRHIQQKSRTLTIDSKEQRNF
LNLNDLFTTGNEILSTFEIKTLSNQPKLSDTVKQIAKTVNEDDGELAELIEERFRETHLAIPETNIALFHAVHSSISSPL
FKIYELSQEIEGMAMDHQMIKINRVLLLLAPPEVPEYVSYLLGKLSSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVK
QYGD

Sequences:

>Translated_644_residues
MFLTSREQKLIHTFLKRGTLTISEMMEITGTSRRTLYRDLNNLQKSLPEEISLQTSEEGYFIKGDIKQLSQAHELVEYTM
TERLYGEILLLIENRASILSLTDYFGISQPTVTNDLRQLEQTLIENEISLIRERGLKIEGLEENIRSVFVAAIYNSASLQ
ELISNQLSDNKLLSILDLDKFKQAYDAFESLILPEDMTDKVRVLMELFLVTTLIRIDEGHFITSESLSSPSKGALNFVNK
LLTALSVTKFVVSEITYLASVYEILYFGFGRELLFMEKFDTDFSYKIRQIIDRVSTKLEIEFGKDDRLYGLLYAHLKESE
MLPILFPKKENDFIKKIKKDNPEIYKAVNESLKLIFDKNFSEMEITFVTLHFVSTLERSDLVLPLRSALVSNRGRISCEF
VMSNLRKNFPFLKKIDLIQNSVKVVKSQYDVIFTTEKEFDYLYINPMLDQKNLDNIRHQLRHIQQKSRTLTIDSKEQRNF
LNLNDLFTTGNEILSTFEIKTLSNQPKLSDTVKQIAKTVNEDDGELAELIEERFRETHLAIPETNIALFHAVHSSISSPL
FKIYELSQEIEGMAMDHQMIKINRVLLLLAPPEVPEYVSYLLGKLSSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVK
QYGD
>Mature_644_residues
MFLTSREQKLIHTFLKRGTLTISEMMEITGTSRRTLYRDLNNLQKSLPEEISLQTSEEGYFIKGDIKQLSQAHELVEYTM
TERLYGEILLLIENRASILSLTDYFGISQPTVTNDLRQLEQTLIENEISLIRERGLKIEGLEENIRSVFVAAIYNSASLQ
ELISNQLSDNKLLSILDLDKFKQAYDAFESLILPEDMTDKVRVLMELFLVTTLIRIDEGHFITSESLSSPSKGALNFVNK
LLTALSVTKFVVSEITYLASVYEILYFGFGRELLFMEKFDTDFSYKIRQIIDRVSTKLEIEFGKDDRLYGLLYAHLKESE
MLPILFPKKENDFIKKIKKDNPEIYKAVNESLKLIFDKNFSEMEITFVTLHFVSTLERSDLVLPLRSALVSNRGRISCEF
VMSNLRKNFPFLKKIDLIQNSVKVVKSQYDVIFTTEKEFDYLYINPMLDQKNLDNIRHQLRHIQQKSRTLTIDSKEQRNF
LNLNDLFTTGNEILSTFEIKTLSNQPKLSDTVKQIAKTVNEDDGELAELIEERFRETHLAIPETNIALFHAVHSSISSPL
FKIYELSQEIEGMAMDHQMIKINRVLLLLAPPEVPEYVSYLLGKLSSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVK
QYGD

Specific function: Not necessary for mannitol utilization. May be involved in regulation of the mannitol phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00359 PTS_EIIA_2 [H]

EC number: NA

Molecular weight: Translated: 74551; Mature: 74551

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTSREQKLIHTFLKRGTLTISEMMEITGTSRRTLYRDLNNLQKSLPEEISLQTSEEGY
CCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCEECCCCE
FIKGDIKQLSQAHELVEYTMTERLYGEILLLIENRASILSLTDYFGISQPTVTNDLRQLE
EEECHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHH
QTLIENEISLIRERGLKIEGLEENIRSVFVAAIYNSASLQELISNQLSDNKLLSILDLDK
HHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
FKQAYDAFESLILPEDMTDKVRVLMELFLVTTLIRIDEGHFITSESLSSPSKGALNFVNK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHH
LLTALSVTKFVVSEITYLASVYEILYFGFGRELLFMEKFDTDFSYKIRQIIDRVSTKLEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHCCEEEE
EFGKDDRLYGLLYAHLKESEMLPILFPKKENDFIKKIKKDNPEIYKAVNESLKLIFDKNF
EECCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SEMEITFVTLHFVSTLERSDLVLPLRSALVSNRGRISCEFVMSNLRKNFPFLKKIDLIQN
CCEEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHH
SVKVVKSQYDVIFTTEKEFDYLYINPMLDQKNLDNIRHQLRHIQQKSRTLTIDSKEQRNF
HHHHHHHCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCHHCCCC
LNLNDLFTTGNEILSTFEIKTLSNQPKLSDTVKQIAKTVNEDDGELAELIEERFRETHLA
CCHHHHHHCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
IPETNIALFHAVHSSISSPLFKIYELSQEIEGMAMDHQMIKINRVLLLLAPPEVPEYVSY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEEEEEECCCCCHHHHHH
LLGKLSSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVKQYGD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLTSREQKLIHTFLKRGTLTISEMMEITGTSRRTLYRDLNNLQKSLPEEISLQTSEEGY
CCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCEECCCCE
FIKGDIKQLSQAHELVEYTMTERLYGEILLLIENRASILSLTDYFGISQPTVTNDLRQLE
EEECHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHH
QTLIENEISLIRERGLKIEGLEENIRSVFVAAIYNSASLQELISNQLSDNKLLSILDLDK
HHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
FKQAYDAFESLILPEDMTDKVRVLMELFLVTTLIRIDEGHFITSESLSSPSKGALNFVNK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHH
LLTALSVTKFVVSEITYLASVYEILYFGFGRELLFMEKFDTDFSYKIRQIIDRVSTKLEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHCCEEEE
EFGKDDRLYGLLYAHLKESEMLPILFPKKENDFIKKIKKDNPEIYKAVNESLKLIFDKNF
EECCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SEMEITFVTLHFVSTLERSDLVLPLRSALVSNRGRISCEFVMSNLRKNFPFLKKIDLIQN
CCEEEEEEHHHHHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHH
SVKVVKSQYDVIFTTEKEFDYLYINPMLDQKNLDNIRHQLRHIQQKSRTLTIDSKEQRNF
HHHHHHHCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCHHCCCC
LNLNDLFTTGNEILSTFEIKTLSNQPKLSDTVKQIAKTVNEDDGELAELIEERFRETHLA
CCHHHHHHCHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
IPETNIALFHAVHSSISSPLFKIYELSQEIEGMAMDHQMIKINRVLLLLAPPEVPEYVSY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEEEEEECCCCCHHHHHH
LLGKLSSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVKQYGD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10878121; 12397186; 1322373 [H]