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The map label for this gene is nadA [H]

Identifier: 124486476

GI number: 124486476

Start: 1698116

End: 1699018

Strand: Reverse

Name: nadA [H]

Synonym: Mlab_1664

Alternate gene names: 124486476

Gene position: 1699018-1698116 (Counterclockwise)

Preceding gene: 124486477

Following gene: 124486475

Centisome position: 94.13

GC content: 56.04

Gene sequence:

>903_bases
ATGAACTATGAAAAAGAGATCAAAAAGCTCGCCGCCGAAAAAGGCGCTTTGATCCTTGCACACAATTATCAGCCGGCCGA
GATCCAGGATCTTGCCGACATCACCGGAGACTCGCTCGAACTTGCCCGCAAGGCAAAGGAAGCAAAGGAGTCGACGCTTG
TCGTCTGCGGCGTCTACTTCATGGCCGAGACGGCAAAGATTCTCTCGCCGGAAAAGACTGTTCTAATCCCAAGACCGGAC
GGCGGATGCCCGCTTGCCGATCAGCTGAACCCTTCAGCGGTTCTTGCAGCGAAAAAAGCCCATCCCGGTTCGCCGTTTGT
TGTGTACGTGAACTCGAATGCGGCAACCAAAGCGGAGTGCGATATCACCTGCACGTCCGCAAATGCCGCGGATGTCGTCC
GTTCCCTTAAGGAAGATACGATCCTGTTTGGTCCGGATGCAAATCTCGCGGCATATGCCCAGCGTCTCGTACCTGAAAAA
ACGATCATCCCCGTCCCGCAAGACGGCGGCTGCCCAACTCACCACCAGTTTTCCGTCCGGGACGTGGAAGCGGCGAGACG
CGAGTATCCGAACGCGACGATCATCTGCCATCCGGAATGCTCTCCCGACGTTCAGCTCGCATCCGATCTGGTCGGCTCGA
CCGGGTACATGATCCGCAGATGCGGCGAAAAGAAAGAGTGGGTGATTCTGACGGAGAAAGGGATCATCCATCCGTTGCAG
AAAAAGTATCCGGACACCATATTCCACGGTATCGATACGGCGGTCTGTTCAAACATGAAACTGATCACGAAAGAGGATCT
CTACATCACGCTTAGGGACGGCGTCGTTCCGATCCAGGTGCCGGAAAGCATCGCGGACCGGGCCCGCCTTGCGATCGAGC
GGATGATCGGGGCATCGGCATAA

Upstream 100 bases:

>100_bases
GAAACGTCCCGTCCCCGGATAATCCGGCAACGAGTTATCTTGCGGCCCTTTCGATCCTCTCGCTTTTGAAAAATCTTGAC
AATCCGCTGGTGATAGGCGC

Downstream 100 bases:

>100_bases
ATGATCCCGACCGACCAGCTTCTCTCGTTCGTTGCCGAGGACGTTTCCGCAGGCGATATCACGACCCTTGCCCTTCTGGA
AGACAATGTGGTCTCGGCCC

Product: quinolinate synthetase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNYEKEIKKLAAEKGALILAHNYQPAEIQDLADITGDSLELARKAKEAKESTLVVCGVYFMAETAKILSPEKTVLIPRPD
GGCPLADQLNPSAVLAAKKAHPGSPFVVYVNSNAATKAECDITCTSANAADVVRSLKEDTILFGPDANLAAYAQRLVPEK
TIIPVPQDGGCPTHHQFSVRDVEAARREYPNATIICHPECSPDVQLASDLVGSTGYMIRRCGEKKEWVILTEKGIIHPLQ
KKYPDTIFHGIDTAVCSNMKLITKEDLYITLRDGVVPIQVPESIADRARLAIERMIGASA

Sequences:

>Translated_300_residues
MNYEKEIKKLAAEKGALILAHNYQPAEIQDLADITGDSLELARKAKEAKESTLVVCGVYFMAETAKILSPEKTVLIPRPD
GGCPLADQLNPSAVLAAKKAHPGSPFVVYVNSNAATKAECDITCTSANAADVVRSLKEDTILFGPDANLAAYAQRLVPEK
TIIPVPQDGGCPTHHQFSVRDVEAARREYPNATIICHPECSPDVQLASDLVGSTGYMIRRCGEKKEWVILTEKGIIHPLQ
KKYPDTIFHGIDTAVCSNMKLITKEDLYITLRDGVVPIQVPESIADRARLAIERMIGASA
>Mature_300_residues
MNYEKEIKKLAAEKGALILAHNYQPAEIQDLADITGDSLELARKAKEAKESTLVVCGVYFMAETAKILSPEKTVLIPRPD
GGCPLADQLNPSAVLAAKKAHPGSPFVVYVNSNAATKAECDITCTSANAADVVRSLKEDTILFGPDANLAAYAQRLVPEK
TIIPVPQDGGCPTHHQFSVRDVEAARREYPNATIICHPECSPDVQLASDLVGSTGYMIRRCGEKKEWVILTEKGIIHPLQ
KKYPDTIFHGIDTAVCSNMKLITKEDLYITLRDGVVPIQVPESIADRARLAIERMIGASA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=257, Percent_Identity=36.9649805447471, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 32591; Mature: 32591

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYEKEIKKLAAEKGALILAHNYQPAEIQDLADITGDSLELARKAKEAKESTLVVCGVYF
CCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEHHHH
MAETAKILSPEKTVLIPRPDGGCPLADQLNPSAVLAAKKAHPGSPFVVYVNSNAATKAEC
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHEEEECCCCCCCCEEEEECCCCCCCCEE
DITCTSANAADVVRSLKEDTILFGPDANLAAYAQRLVPEKTIIPVPQDGGCPTHHQFSVR
EEEEECCCHHHHHHHHHHCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHH
DVEAARREYPNATIICHPECSPDVQLASDLVGSTGYMIRRCGEKKEWVILTEKGIIHPLQ
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHH
KKYPDTIFHGIDTAVCSNMKLITKEDLYITLRDGVVPIQVPESIADRARLAIERMIGASA
HHCCHHHHHHCHHHHHCCCEEEEECCEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNYEKEIKKLAAEKGALILAHNYQPAEIQDLADITGDSLELARKAKEAKESTLVVCGVYF
CCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCEEEEEHHHH
MAETAKILSPEKTVLIPRPDGGCPLADQLNPSAVLAAKKAHPGSPFVVYVNSNAATKAEC
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHEEEECCCCCCCCEEEEECCCCCCCCEE
DITCTSANAADVVRSLKEDTILFGPDANLAAYAQRLVPEKTIIPVPQDGGCPTHHQFSVR
EEEEECCCHHHHHHHHHHCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHH
DVEAARREYPNATIICHPECSPDVQLASDLVGSTGYMIRRCGEKKEWVILTEKGIIHPLQ
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCHHH
KKYPDTIFHGIDTAVCSNMKLITKEDLYITLRDGVVPIQVPESIADRARLAIERMIGASA
HHCCHHHHHHCHHHHHCCCEEEEECCEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA