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The map label for this gene is 124486449

Identifier: 124486449

GI number: 124486449

Start: 1663171

End: 1664058

Strand: Reverse

Name: 124486449

Synonym: Mlab_1637

Alternate gene names: NA

Gene position: 1664058-1663171 (Counterclockwise)

Preceding gene: 124486454

Following gene: 124486448

Centisome position: 92.19

GC content: 55.41

Gene sequence:

>888_bases
ATGGTTGATTTCCCTCACGCTATCTATATCCCCCACAACCTCCCACATTACTATATGCACTGGTATGGGGAAGCTGGAGA
TCTGTCGACGGACACGGCCGCATGCGAAGAACGGGTACTGAATACTACTACGATACCGTCCGTTCTTTGTAACTGGGAAG
ACCTCCGGGATGCCGGCCTGATCTCATCCAGAGATGAATACATCCGGGCGGTCAGGGAGGTCACGTTTTCTCTCGCGGAA
AAAGGCATCGCCGCCGATCTTGACAAAAAAGATGCCGCTCTCCTCCAGATGGTTCGGACCCTCGATGAGATGGATGATGT
GATCAACCTCTTAACGGAAAGAGTGACCGACTGGCATGCGGCGACGACGCCTGGGACCTCGCATAAATATACCCGGTCGA
ACGGTCCCCGTCTCGTCCAGAAGATCGCAAAATCCGGGAGTCCTTCCTTAAAACGTGTAGCACGAGAGATCCTCTCTCTT
TCCGGAGTCAGAACCGATCTCATGAAAGAAGTCTCCCGGGAAGCCGTGAGCGTTATCCCGAATATGAGCGCCCTTGTCGG
CGGTCTTGTTGCCGCACGGCTGATTGCCCGTGCCGGCGGTCTTGATGCGGCGGCAAAAATGCCCGGCTCATCCATTCAGG
TGATCGGCGCCGAGTCTGCCCTCTTTTCCCACATCAGAACGGGTTCTTCCTCGCCCAAACACGGAATCATCTTCCAGCAC
CGGCGTGTTCACAACGCCAAAAAGGAGGTCCGCGGAAAAGTTGCCCGTCAGCTTGCCGCAAAACTCGCGATCGCCGCCCG
TCTGGATCTGTATCGGGGCGAACTTGATCCCGAATTCGTCGATCAGGCGAATGCCAAAATCGACAGCATTTTCGGAGGGG
AAGCATGA

Upstream 100 bases:

>100_bases
GCTCGGCATGCCGAGAGCGTCACCAAGGATTGATCCTACAAGGCATCCTTTGTAGTTATTAAGCATGATGTATTATTGAG
AGAGGTTTGTGTTAATTGTT

Downstream 100 bases:

>100_bases
TTCAGATCAACGGCACGCTCGTCTCCGAAGGCCCCGGAGGAGTGTACAATGAGCGGATGCTTGGAAACTTCCGTGTCTGG
GATCCGTACCGGAGCAAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MVDFPHAIYIPHNLPHYYMHWYGEAGDLSTDTAACEERVLNTTTIPSVLCNWEDLRDAGLISSRDEYIRAVREVTFSLAE
KGIAADLDKKDAALLQMVRTLDEMDDVINLLTERVTDWHAATTPGTSHKYTRSNGPRLVQKIAKSGSPSLKRVAREILSL
SGVRTDLMKEVSREAVSVIPNMSALVGGLVAARLIARAGGLDAAAKMPGSSIQVIGAESALFSHIRTGSSSPKHGIIFQH
RRVHNAKKEVRGKVARQLAAKLAIAARLDLYRGELDPEFVDQANAKIDSIFGGEA

Sequences:

>Translated_295_residues
MVDFPHAIYIPHNLPHYYMHWYGEAGDLSTDTAACEERVLNTTTIPSVLCNWEDLRDAGLISSRDEYIRAVREVTFSLAE
KGIAADLDKKDAALLQMVRTLDEMDDVINLLTERVTDWHAATTPGTSHKYTRSNGPRLVQKIAKSGSPSLKRVAREILSL
SGVRTDLMKEVSREAVSVIPNMSALVGGLVAARLIARAGGLDAAAKMPGSSIQVIGAESALFSHIRTGSSSPKHGIIFQH
RRVHNAKKEVRGKVARQLAAKLAIAARLDLYRGELDPEFVDQANAKIDSIFGGEA
>Mature_295_residues
MVDFPHAIYIPHNLPHYYMHWYGEAGDLSTDTAACEERVLNTTTIPSVLCNWEDLRDAGLISSRDEYIRAVREVTFSLAE
KGIAADLDKKDAALLQMVRTLDEMDDVINLLTERVTDWHAATTPGTSHKYTRSNGPRLVQKIAKSGSPSLKRVAREILSL
SGVRTDLMKEVSREAVSVIPNMSALVGGLVAARLIARAGGLDAAAKMPGSSIQVIGAESALFSHIRTGSSSPKHGIIFQH
RRVHNAKKEVRGKVARQLAAKLAIAARLDLYRGELDPEFVDQANAKIDSIFGGEA

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=229, Percent_Identity=27.5109170305677, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7706254, Length=220, Percent_Identity=25.9090909090909, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI221136939, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509449, Length=232, Percent_Identity=30.1724137931034, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562296, Length=238, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17510923, Length=118, Percent_Identity=33.0508474576271, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324886, Length=218, Percent_Identity=28.4403669724771, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323226, Length=229, Percent_Identity=25.3275109170306, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17137636, Length=149, Percent_Identity=35.5704697986577, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28572126, Length=226, Percent_Identity=25.6637168141593, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357435, Length=224, Percent_Identity=25, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 32208; Mature: 32208

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFPHAIYIPHNLPHYYMHWYGEAGDLSTDTAACEERVLNTTTIPSVLCNWEDLRDAGL
CCCCCCEEECCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
ISSRDEYIRAVREVTFSLAEKGIAADLDKKDAALLQMVRTLDEMDDVINLLTERVTDWHA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATTPGTSHKYTRSNGPRLVQKIAKSGSPSLKRVAREILSLSGVRTDLMKEVSREAVSVIP
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
NMSALVGGLVAARLIARAGGLDAAAKMPGSSIQVIGAESALFSHIRTGSSSPKHGIIFQH
CHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEHH
RRVHNAKKEVRGKVARQLAAKLAIAARLDLYRGELDPEFVDQANAKIDSIFGGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MVDFPHAIYIPHNLPHYYMHWYGEAGDLSTDTAACEERVLNTTTIPSVLCNWEDLRDAGL
CCCCCCEEECCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
ISSRDEYIRAVREVTFSLAEKGIAADLDKKDAALLQMVRTLDEMDDVINLLTERVTDWHA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ATTPGTSHKYTRSNGPRLVQKIAKSGSPSLKRVAREILSLSGVRTDLMKEVSREAVSVIP
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
NMSALVGGLVAARLIARAGGLDAAAKMPGSSIQVIGAESALFSHIRTGSSSPKHGIIFQH
CHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEHH
RRVHNAKKEVRGKVARQLAAKLAIAARLDLYRGELDPEFVDQANAKIDSIFGGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]