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The map label for this gene is yqeF [C]

Identifier: 124486438

GI number: 124486438

Start: 1652759

End: 1653922

Strand: Reverse

Name: yqeF [C]

Synonym: Mlab_1626

Alternate gene names: 124486438

Gene position: 1653922-1652759 (Counterclockwise)

Preceding gene: 124486439

Following gene: 124486437

Centisome position: 91.63

GC content: 57.9

Gene sequence:

>1164_bases
ATGAGAGATGTAGCAGTAATAGGTGCAGGAATCACGAAATTCGGAGAAAGATGGGACACATCTTTCCGTGATCTGTGTAC
AGAAGCAGGAATCGCCGCACTTGAAGATGCAAATGTGGCGGGCGAACAGATCGATGCATTGTTCGTCGGTTCGATGTCCG
CCGGAAGATTCGTCGGTCAGGAACATGTCGGGGCACTCGTTGCCGATTACGTAGGACTCGGCGGAGACCTCCACACCCCG
GCTACCCGTGTTGAAGCTGCCTGTGCCTCCGGAGGCCTTGCCTTCCGTCAGGCCGTAGCAGCAGTTTCTTCCGGCATGTC
CGATGTCGTTATCGCGGCAGGTGTCGAGAAGATGACTGATGTCGGCGATTCGACGGATGTCCTTGCCGGAGCCGCTGACA
GAGAGTGGGAAAGCTTTGCAGGAGCAACTTTCCCCGGTCTGTATGCGATGATCGCCTGCGACTACATGCACAAATACGGA
CTGACCCGCGAGCAGCTTGCCCAGGTTGCGGTGAAAAACCACTTCCACGGAGCAAGAAACCCGTATGCGCAGTTCCAGAA
CGAGATCACCCAGGCTACGGTGATGAACTCAACGCTCGTTGCCTCCCCGCTTAGGCTCTTCGACTGCTCGCCCGTTTCCG
ACGGTGCCGCGGTCGTTGTCGTCTGCCCGCTTGAAAAAGCACGGGAGTTTACCGACACGCCGATCAAGGTCCTTGCCTCA
GCCCAGGCCGGCGATACGATCGCTTTACACGACCGCCCGGACTTTTCCACGATGGGTGCCACGGTCGCCGCAGGAAACTC
CGCGTTCCGTCAGGCAAAACTCGAACGAAAGGACATCGACTTCGTTGAAGTTCACGACTGTTTCACGATCGCCGAACTTT
GTGCGATCGAGGATCTCGGCTTCGTTCCGAAGGGAACTGCCGGCAAATTCACCGAGCAGGGCGAGACCCAGCTTGGCGGA
AAGCTTCCGGTAAACACGTCCGGAGGTCTCAAGGCATGCGGCCACCCGGTCGGAGCCACCGGTATCAAACAGATCTGGGA
AGTCGTCCAGCAGCTTCGCGGCGAAGGCGGCAAACGTCAGGTCGAAGGAGCAGAAATAGGTATGACCCAGAACGTCGGAG
GAACCGGCGCAACCGTTGTATCGCACATCTTCGGGAGGGCCTGA

Upstream 100 bases:

>100_bases
CCCAGGGTCCGTCCGTTGAACAGATGCTTTCCACAAAGAAGTATCTTGACTATGCAGTGTATGCCCGGCACAAGGGCAAG
ATCCGGATGTGAGGTGTATC

Downstream 100 bases:

>100_bases
GATGACCGTAGCACGATTCTGGAGAGAGATTCCCCAGAGATACAATATGGTCGGAACGAAATGCGATATCTGCGGGGATG
TATTCTTCCCGCCAAGAGCA

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MRDVAVIGAGITKFGERWDTSFRDLCTEAGIAALEDANVAGEQIDALFVGSMSAGRFVGQEHVGALVADYVGLGGDLHTP
ATRVEAACASGGLAFRQAVAAVSSGMSDVVIAAGVEKMTDVGDSTDVLAGAADREWESFAGATFPGLYAMIACDYMHKYG
LTREQLAQVAVKNHFHGARNPYAQFQNEITQATVMNSTLVASPLRLFDCSPVSDGAAVVVVCPLEKAREFTDTPIKVLAS
AQAGDTIALHDRPDFSTMGATVAAGNSAFRQAKLERKDIDFVEVHDCFTIAELCAIEDLGFVPKGTAGKFTEQGETQLGG
KLPVNTSGGLKACGHPVGATGIKQIWEVVQQLRGEGGKRQVEGAEIGMTQNVGGTGATVVSHIFGRA

Sequences:

>Translated_387_residues
MRDVAVIGAGITKFGERWDTSFRDLCTEAGIAALEDANVAGEQIDALFVGSMSAGRFVGQEHVGALVADYVGLGGDLHTP
ATRVEAACASGGLAFRQAVAAVSSGMSDVVIAAGVEKMTDVGDSTDVLAGAADREWESFAGATFPGLYAMIACDYMHKYG
LTREQLAQVAVKNHFHGARNPYAQFQNEITQATVMNSTLVASPLRLFDCSPVSDGAAVVVVCPLEKAREFTDTPIKVLAS
AQAGDTIALHDRPDFSTMGATVAAGNSAFRQAKLERKDIDFVEVHDCFTIAELCAIEDLGFVPKGTAGKFTEQGETQLGG
KLPVNTSGGLKACGHPVGATGIKQIWEVVQQLRGEGGKRQVEGAEIGMTQNVGGTGATVVSHIFGRA
>Mature_387_residues
MRDVAVIGAGITKFGERWDTSFRDLCTEAGIAALEDANVAGEQIDALFVGSMSAGRFVGQEHVGALVADYVGLGGDLHTP
ATRVEAACASGGLAFRQAVAAVSSGMSDVVIAAGVEKMTDVGDSTDVLAGAADREWESFAGATFPGLYAMIACDYMHKYG
LTREQLAQVAVKNHFHGARNPYAQFQNEITQATVMNSTLVASPLRLFDCSPVSDGAAVVVVCPLEKAREFTDTPIKVLAS
AQAGDTIALHDRPDFSTMGATVAAGNSAFRQAKLERKDIDFVEVHDCFTIAELCAIEDLGFVPKGTAGKFTEQGETQLGG
KLPVNTSGGLKACGHPVGATGIKQIWEVVQQLRGEGGKRQVEGAEIGMTQNVGGTGATVVSHIFGRA

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=398, Percent_Identity=32.6633165829146, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI302344760, Length=398, Percent_Identity=30.9045226130653, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI302344767, Length=316, Percent_Identity=33.2278481012658, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI302344762, Length=398, Percent_Identity=30.6532663316583, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI55956775, Length=358, Percent_Identity=28.4916201117318, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17537653, Length=398, Percent_Identity=32.1608040201005, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI19921506, Length=396, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24585051, Length=396, Percent_Identity=32.8282828282828, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40460; Mature: 40460

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVAVIGAGITKFGERWDTSFRDLCTEAGIAALEDANVAGEQIDALFVGSMSAGRFVGQ
CCCEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCHHHHCEEEECCCCCCCCCCH
EHVGALVADYVGLGGDLHTPATRVEAACASGGLAFRQAVAAVSSGMSDVVIAAGVEKMTD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHCHHHHHH
VGDSTDVLAGAADREWESFAGATFPGLYAMIACDYMHKYGLTREQLAQVAVKNHFHGARN
CCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
PYAQFQNEITQATVMNSTLVASPLRLFDCSPVSDGAAVVVVCPLEKAREFTDTPIKVLAS
HHHHHHHHHHHHHHHCCHHHHCCHHHEECCCCCCCCEEEEECCCHHHHHCCCCHHHHHHH
AQAGDTIALHDRPDFSTMGATVAAGNSAFRQAKLERKDIDFVEVHDCFTIAELCAIEDLG
CCCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCC
FVPKGTAGKFTEQGETQLGGKLPVNTSGGLKACGHPVGATGIKQIWEVVQQLRGEGGKRQ
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VEGAEIGMTQNVGGTGATVVSHIFGRA
CCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRDVAVIGAGITKFGERWDTSFRDLCTEAGIAALEDANVAGEQIDALFVGSMSAGRFVGQ
CCCEEEECCCHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCHHHHCEEEECCCCCCCCCCH
EHVGALVADYVGLGGDLHTPATRVEAACASGGLAFRQAVAAVSSGMSDVVIAAGVEKMTD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEHHHCHHHHHH
VGDSTDVLAGAADREWESFAGATFPGLYAMIACDYMHKYGLTREQLAQVAVKNHFHGARN
CCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
PYAQFQNEITQATVMNSTLVASPLRLFDCSPVSDGAAVVVVCPLEKAREFTDTPIKVLAS
HHHHHHHHHHHHHHHCCHHHHCCHHHEECCCCCCCCEEEEECCCHHHHHCCCCHHHHHHH
AQAGDTIALHDRPDFSTMGATVAAGNSAFRQAKLERKDIDFVEVHDCFTIAELCAIEDLG
CCCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCC
FVPKGTAGKFTEQGETQLGGKLPVNTSGGLKACGHPVGATGIKQIWEVVQQLRGEGGKRQ
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCEE
VEGAEIGMTQNVGGTGATVVSHIFGRA
CCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]