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The map label for this gene is pfdA

Identifier: 124486293

GI number: 124486293

Start: 1516682

End: 1517125

Strand: Reverse

Name: pfdA

Synonym: Mlab_1477

Alternate gene names: 124486293

Gene position: 1517125-1516682 (Counterclockwise)

Preceding gene: 124486294

Following gene: 124486291

Centisome position: 84.05

GC content: 53.83

Gene sequence:

>444_bases
ATGGCGAGTAATACTGATCAGGCATCCCTGGAGCAGGAGGTCCGCTCCCTCCAGGCATATGCCAATGAATATTCCCAGCA
GTTTGAACTTCTGACCCAGCAGCTGCGTTTCATCGAATCAGCACGCGGGGAAGCTTTAGCGTCCACCGAGTCGCTTGAAG
CTTTCAGCGGTCTGGAAGGAGATGTACCCACTCTTCTGAATCTGGGCGGGGGCATATCAGTTCATGCCATCGTCACCGAC
ACGAAGAAGATCCTGGTTGGGATCGGCGCAGGCATCACGGTTGAAAAACCGGTCGAAGAAGCGATCACGTTCCTTCACGA
CCGGGTCACTGAGATGGATGCATCCGCAAAACGGCTTTCTGAGTCTCTTGGAAAGCTTCAGGAACAGATGCGGGCCGTTG
AGCAGAGAATGCAGGAAATCTATTCTCAGACTCAGCACCGCTGA

Upstream 100 bases:

>100_bases
CCTTCCGAGAAACTTGCTGGAGAATTCACTCTTGCAACGATCGGAAGCAAGCACAGACTCGAACGCAAGTATATTACCAT
TGACGCTGCAAAGGCTATTA

Downstream 100 bases:

>100_bases
ACTTCTCTTTTTTCCCGTTCCGTTCGCCATCACGCAAAACGCCTAAGTGTTTCAAAAAAAGGCGGGTGTTATCTTCTTTT
GATCAGCAGGAAAGCGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: GimC subunit alpha

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MASNTDQASLEQEVRSLQAYANEYSQQFELLTQQLRFIESARGEALASTESLEAFSGLEGDVPTLLNLGGGISVHAIVTD
TKKILVGIGAGITVEKPVEEAITFLHDRVTEMDASAKRLSESLGKLQEQMRAVEQRMQEIYSQTQHR

Sequences:

>Translated_147_residues
MASNTDQASLEQEVRSLQAYANEYSQQFELLTQQLRFIESARGEALASTESLEAFSGLEGDVPTLLNLGGGISVHAIVTD
TKKILVGIGAGITVEKPVEEAITFLHDRVTEMDASAKRLSESLGKLQEQMRAVEQRMQEIYSQTQHR
>Mature_146_residues
ASNTDQASLEQEVRSLQAYANEYSQQFELLTQQLRFIESARGEALASTESLEAFSGLEGDVPTLLNLGGGISVHAIVTDT
KKILVGIGAGITVEKPVEEAITFLHDRVTEMDASAKRLSESLGKLQEQMRAVEQRMQEIYSQTQHR

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin alpha subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA_METLZ (A2STI6)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030909.1
- ProteinModelPortal:   A2STI6
- SMR:   A2STI6
- STRING:   A2STI6
- GeneID:   4795099
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_1477
- eggNOG:   arNOG11546
- HOGENOM:   HBG541673
- OMA:   LLQIGGG
- BioCyc:   MLAB410358:MLAB_1477-MONOMER
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 16212; Mature: 16081

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNTDQASLEQEVRSLQAYANEYSQQFELLTQQLRFIESARGEALASTESLEAFSGLEG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
DVPTLLNLGGGISVHAIVTDTKKILVGIGAGITVEKPVEEAITFLHDRVTEMDASAKRLS
CHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLGKLQEQMRAVEQRMQEIYSQTQHR
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASNTDQASLEQEVRSLQAYANEYSQQFELLTQQLRFIESARGEALASTESLEAFSGLEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
DVPTLLNLGGGISVHAIVTDTKKILVGIGAGITVEKPVEEAITFLHDRVTEMDASAKRLS
CHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLGKLQEQMRAVEQRMQEIYSQTQHR
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA