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The map label for this gene is yecS [H]

Identifier: 124486251

GI number: 124486251

Start: 1464282

End: 1465049

Strand: Reverse

Name: yecS [H]

Synonym: Mlab_1435

Alternate gene names: 124486251

Gene position: 1465049-1464282 (Counterclockwise)

Preceding gene: 124486252

Following gene: 124486250

Centisome position: 81.17

GC content: 49.61

Gene sequence:

>768_bases
ATGGATAATCTGACCAGTACATCTGTGCCTGCAGACGGGATAAGCGGATTTTTCCAGAACGCCATAGACTCGTTCGTTTC
CCAAATACCCTTCTGGCAGGATATTCTGCTCCCAGCTCTCTGGGATGGGTTAGTGGTGACGATCCAGCTTGTGCTCATGA
CGGCACCACTCGGTCTCCTTCTTGGTCTTCTTGTGGCTGTATCCAGAGTTTACGGGCCCACGCCGGTCAAATGGCTTGCA
AAACTGTATGTCATCTTTTTCCGTGGATGTCCGCTTCTTGTTCTGCTGTTTATTCTGTACTTTGGTCTGCCGTCGATCGG
GATCGTTCTCGGATCCTATTTCTCTGCTCTTGTCGGGTTTATTTTGTGTAACTCGGCATATAACTCCGAGTATCTCCGTG
GGGGACTCCAGTCGATAAAACGCGGTCAGCTGCTTGCGGCCAGATCACTTGGCATGACGAAAGCACAGGGAGTTATGTAT
GTGGTTGTCCCGCAGGCACTTCGCCGTGCTCTTCCGGGTGTTTCAAACGAGTTTATTTATCTGATAAAATACTCGTCGCT
GGCCTATGTGGTTGCGGTAATCGAACTTACCGGTGCGGCAAAAATTATTGCAAGCAAGTACTTCATGTACTTCGAGGCAT
TTGCGGCAGTAGGAGTTTTCTATCTGATTCTCGTGACGATCACAACGATCGGTGTCCACTGGCTTGAGAAGAAGTATGCG
ATCCCCGGCGTCTCGGGCGTTGTTGGAAAAGTCACCAAAGAACACTAA

Upstream 100 bases:

>100_bases
AAGGGAGAGATCGTTGAACACGGTCCGCCGTCAGAGATCCCGACAAGTCCGAATTTTGTGAAAACACGTGCGTTTATGGG
CAGTTACGCAGACGAGTGAT

Downstream 100 bases:

>100_bases
ATCCTTTTAGAAATCTTTTAAATATTCTGTTTTCCTATTCTCTATCATGTCATTATCTGTTGATGTTATAGACAAACTCG
CTGCGCTTATCACCGCAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDNLTSTSVPADGISGFFQNAIDSFVSQIPFWQDILLPALWDGLVVTIQLVLMTAPLGLLLGLLVAVSRVYGPTPVKWLA
KLYVIFFRGCPLLVLLFILYFGLPSIGIVLGSYFSALVGFILCNSAYNSEYLRGGLQSIKRGQLLAARSLGMTKAQGVMY
VVVPQALRRALPGVSNEFIYLIKYSSLAYVVAVIELTGAAKIIASKYFMYFEAFAAVGVFYLILVTITTIGVHWLEKKYA
IPGVSGVVGKVTKEH

Sequences:

>Translated_255_residues
MDNLTSTSVPADGISGFFQNAIDSFVSQIPFWQDILLPALWDGLVVTIQLVLMTAPLGLLLGLLVAVSRVYGPTPVKWLA
KLYVIFFRGCPLLVLLFILYFGLPSIGIVLGSYFSALVGFILCNSAYNSEYLRGGLQSIKRGQLLAARSLGMTKAQGVMY
VVVPQALRRALPGVSNEFIYLIKYSSLAYVVAVIELTGAAKIIASKYFMYFEAFAAVGVFYLILVTITTIGVHWLEKKYA
IPGVSGVVGKVTKEH
>Mature_255_residues
MDNLTSTSVPADGISGFFQNAIDSFVSQIPFWQDILLPALWDGLVVTIQLVLMTAPLGLLLGLLVAVSRVYGPTPVKWLA
KLYVIFFRGCPLLVLLFILYFGLPSIGIVLGSYFSALVGFILCNSAYNSEYLRGGLQSIKRGQLLAARSLGMTKAQGVMY
VVVPQALRRALPGVSNEFIYLIKYSSLAYVVAVIELTGAAKIIASKYFMYFEAFAAVGVFYLILVTITTIGVHWLEKKYA
IPGVSGVVGKVTKEH

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=198, Percent_Identity=41.9191919191919, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786873, Length=219, Percent_Identity=34.2465753424658, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=31.8840579710145, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788645, Length=210, Percent_Identity=29.5238095238095, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787086, Length=212, Percent_Identity=27.3584905660377, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786874, Length=235, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=32.8502415458937, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787087, Length=207, Percent_Identity=26.5700483091787, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788646, Length=216, Percent_Identity=24.537037037037, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27790; Mature: 27790

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHCCC
>Mature Secondary Structure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CCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]