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The map label for this gene is egsA

Identifier: 124486126

GI number: 124486126

Start: 1332135

End: 1333217

Strand: Reverse

Name: egsA

Synonym: Mlab_1308

Alternate gene names: 124486126

Gene position: 1333217-1332135 (Counterclockwise)

Preceding gene: 124486129

Following gene: 124486125

Centisome position: 73.86

GC content: 55.12

Gene sequence:

>1083_bases
ATGGAAGCTAAGAATAATAGGATACTCAAGGATAAAACCTTTGACAAATCCCGGTGGATTCAGATGCCGAGGGATGTGAT
CGCCGGTCACGATGCTTTGCTTCAGCTTCCTAACGTCATCACCGATCTGGGTGTCACCGGTCCATTACTTCTTCTTTCGG
GAAAAACGACCCTGCAGACCGTGGGTCTCGAGGTTCTCCGGCTTTTGGAAGACCGACAGGTCACAAGCGCAGTAGTCGGG
GAGATCACCTATGAGGAGATCGCGAGGGTCGAGGATCTGGCGCAAAACATCGGTGCGGTTTTGATCATCGCTGTGGGTGG
AGGCCGGGTTATCGATACGGCCAAGGTCGTCTCCTACAATCTCGATATCCAGTTCATCAGTGTTCCAACCGCCGCATCCC
ATGACGGTATCGCCTCTTCGCGGGCCTCGATCATGACGGCAGACGGGAATGTGAGCGTGGCGGCCCATCCGCCGCTCGCC
ATCGTCGCCGACACGGGAATTATAGCGGGGGCCCCGCACCGGCTGATGGCTGCCGGGTATGCGGATATGGTGGCAAACTA
TACCGCCGTCATGGATTGGGATCTTTCAAAATCAAAGACCGGCGAACAGGTCAGCGAATATGCGATGACGCTCTCCATGA
TAACCGCCGAACTGATGGTGGAGAATGCGGAAAAGATCAAGGCCTTCGATGAAAATGCGGCCTGGATCGTTGTAAAGGCG
TTGTTTGCCTCCGGCGTTGCGATGAGTATCGCCGGAAGTTCCCGCCCGGCATCGGGAGGTGAACACAAGTTTGCCCATAT
GCTCGAACGTCTGGTTCCCGGAAAAGTCCTTCACGGGGAAGCCTGCGGGGTTGGGACCATCATCAGTATGATCATGCACG
AAGGAGACTGGAAAAAGATCCGGAACTCTCTTCGGTTGATCGGCGCCCCGACAACGCCGAAGGATCTCGGCATTTCCGAC
GAGATCGTCATTGAGGCAATTCTTCGGGCAAAAGAGATCCGCCCTGAGCGCTACACCATCTTTGATGAGGATATTACCAG
AGAGCAGGCCGAGTGTCTGGTCGCCCGCTTATATGAGGAGTAA

Upstream 100 bases:

>100_bases
ACTAATAAAGCATACAAAATCGTCTGGATGACCGTATAGGTTGAGCCCTCCAGTTCGACTATCCACGCATATAATTCATT
AAACATATAGGATCACGACC

Downstream 100 bases:

>100_bases
ATCATGGATAAGGAAGAAACAATCGTAACAATCGTCGGCTCGGTTTTAGCTCATGAGGGTGCCGAGTTCGTGTATGCCGG
AAAAGCAGCCGAATGCGAAT

Product: NAD(P)-dependent glycerol-1-phosphate dehydrogenase

Products: NA

Alternate protein names: G1P dehydrogenase; G1PDH; Enantiomeric glycerophosphate synthase; sn-glycerol-1-phosphate dehydrogenase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEAKNNRILKDKTFDKSRWIQMPRDVIAGHDALLQLPNVITDLGVTGPLLLLSGKTTLQTVGLEVLRLLEDRQVTSAVVG
EITYEEIARVEDLAQNIGAVLIIAVGGGRVIDTAKVVSYNLDIQFISVPTAASHDGIASSRASIMTADGNVSVAAHPPLA
IVADTGIIAGAPHRLMAAGYADMVANYTAVMDWDLSKSKTGEQVSEYAMTLSMITAELMVENAEKIKAFDENAAWIVVKA
LFASGVAMSIAGSSRPASGGEHKFAHMLERLVPGKVLHGEACGVGTIISMIMHEGDWKKIRNSLRLIGAPTTPKDLGISD
EIVIEAILRAKEIRPERYTIFDEDITREQAECLVARLYEE

Sequences:

>Translated_360_residues
MEAKNNRILKDKTFDKSRWIQMPRDVIAGHDALLQLPNVITDLGVTGPLLLLSGKTTLQTVGLEVLRLLEDRQVTSAVVG
EITYEEIARVEDLAQNIGAVLIIAVGGGRVIDTAKVVSYNLDIQFISVPTAASHDGIASSRASIMTADGNVSVAAHPPLA
IVADTGIIAGAPHRLMAAGYADMVANYTAVMDWDLSKSKTGEQVSEYAMTLSMITAELMVENAEKIKAFDENAAWIVVKA
LFASGVAMSIAGSSRPASGGEHKFAHMLERLVPGKVLHGEACGVGTIISMIMHEGDWKKIRNSLRLIGAPTTPKDLGISD
EIVIEAILRAKEIRPERYTIFDEDITREQAECLVARLYEE
>Mature_360_residues
MEAKNNRILKDKTFDKSRWIQMPRDVIAGHDALLQLPNVITDLGVTGPLLLLSGKTTLQTVGLEVLRLLEDRQVTSAVVG
EITYEEIARVEDLAQNIGAVLIIAVGGGRVIDTAKVVSYNLDIQFISVPTAASHDGIASSRASIMTADGNVSVAAHPPLA
IVADTGIIAGAPHRLMAAGYADMVANYTAVMDWDLSKSKTGEQVSEYAMTLSMITAELMVENAEKIKAFDENAAWIVVKA
LFASGVAMSIAGSSRPASGGEHKFAHMLERLVPGKVLHGEACGVGTIISMIMHEGDWKKIRNSLRLIGAPTTPKDLGISD
EIVIEAILRAKEIRPERYTIFDEDITREQAECLVARLYEE

Specific function: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol-1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerol-1-phosphate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI87082352, Length=318, Percent_Identity=24.2138364779874, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G1PDH_METLZ (A2ST19)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030742.1
- ProteinModelPortal:   A2ST19
- SMR:   A2ST19
- STRING:   A2ST19
- GeneID:   4794656
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_1308
- eggNOG:   arNOG04488
- HOGENOM:   HBG672951
- OMA:   NRHTILR
- PhylomeDB:   A2ST19
- ProtClustDB:   PRK00843
- BioCyc:   MLAB410358:MLAB_1308-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00497_A
- InterPro:   IPR002658
- InterPro:   IPR023002
- InterPro:   IPR016205
- PIRSF:   PIRSF000112

Pfam domain/function: PF01761 DHQ_synthase

EC number: =1.1.1.261

Molecular weight: Translated: 38858; Mature: 38858

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: BINDING 135-135 BINDING 139-139 BINDING 182-182 BINDING 266-266

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKNNRILKDKTFDKSRWIQMPRDVIAGHDALLQLPNVITDLGVTGPLLLLSGKTTLQT
CCCCCCCEECCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
VGLEVLRLLEDRQVTSAVVGEITYEEIARVEDLAQNIGAVLIIAVGGGRVIDTAKVVSYN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEEEEEE
LDIQFISVPTAASHDGIASSRASIMTADGNVSVAAHPPLAIVADTGIIAGAPHRLMAAGY
CEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEECCCEECCCCHHHHHHHH
ADMVANYTAVMDWDLSKSKTGEQVSEYAMTLSMITAELMVENAEKIKAFDENAAWIVVKA
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHH
LFASGVAMSIAGSSRPASGGEHKFAHMLERLVPGKVLHGEACGVGTIISMIMHEGDWKKI
HHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCHHHH
RNSLRLIGAPTTPKDLGISDEIVIEAILRAKEIRPERYTIFDEDITREQAECLVARLYEE
HHCCEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAKNNRILKDKTFDKSRWIQMPRDVIAGHDALLQLPNVITDLGVTGPLLLLSGKTTLQT
CCCCCCCEECCCCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
VGLEVLRLLEDRQVTSAVVGEITYEEIARVEDLAQNIGAVLIIAVGGGRVIDTAKVVSYN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEEEEEEE
LDIQFISVPTAASHDGIASSRASIMTADGNVSVAAHPPLAIVADTGIIAGAPHRLMAAGY
CEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEEECCCEEEEECCCEECCCCHHHHHHHH
ADMVANYTAVMDWDLSKSKTGEQVSEYAMTLSMITAELMVENAEKIKAFDENAAWIVVKA
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHH
LFASGVAMSIAGSSRPASGGEHKFAHMLERLVPGKVLHGEACGVGTIISMIMHEGDWKKI
HHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCHHHH
RNSLRLIGAPTTPKDLGISDEIVIEAILRAKEIRPERYTIFDEDITREQAECLVARLYEE
HHCCEEEECCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA