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The map label for this gene is 124485958

Identifier: 124485958

GI number: 124485958

Start: 1151485

End: 1152165

Strand: Reverse

Name: 124485958

Synonym: Mlab_1138

Alternate gene names: NA

Gene position: 1152165-1151485 (Counterclockwise)

Preceding gene: 124485959

Following gene: 124485957

Centisome position: 63.83

GC content: 56.39

Gene sequence:

>681_bases
ATGAACTGGCAAACCTGGCGCCACATCACGAAGCTTGACCCCGACAAGGTCATAACCAAAGAAGAGATCGCAGAGATCGC
GGCAAGCGAAACGGACGCTCTCATGCTTTCCGGGACTCTCGACGTTACTCCTGAAAACCTCGCCGAGCTGTATGACAATG
TTCGGGATGCGGGTCTCCCGCTCACCGTCGAACCGGCGGATCCCTCCTGTGCGAGATTCGAAGGGATCGACTATGTGTTC
GTTCCAAGCGTGTTCAATGCGGGTCATCCGGCATTCATCACCGGACTGCACAAAGAGTGGGCACAGCATGCGGATATCCT
GTGGGACAAAGTCGTCCAGGAAGCGTATGTGGTTTTGAACCCGAACTCGTCCGTGGGCAAACTCACCCGTGCCAAATGCG
ACCTCACCCCGGCAGAGGTGGCGGCCTATGGTATCGTTGCTGAGAAATACTACTCGATGCCTGTGTTGTACATCGAGTAC
AGCGGGATGTACGGCGATCCGGCGGTCACTCGTGCCGTTTCCGAAGCCCTTTCAACGACCCGCGTCTTTTACGGCGGAGG
GATCAACTCCGGCGCAAAAGCTGCAGAAATGGGTCAGTATGCCGACACGATCGTTGTCGGAAACGCGGTCTACGAGGCCG
GCCCTGCTGTTTTGAAAGAGACGGTGAAGGCGGTCAAATAA

Upstream 100 bases:

>100_bases
TGCTGGTAAAGGCCGATGCGAAGACACTTGCAAAAGTTACCGGTATCGATGAAAAACAGATTGTTAATCTGCAAAAGTAT
GCACAAAAGGTGTTAGAAAA

Downstream 100 bases:

>100_bases
TGCCCCAGATCGACATCGTGCTAGTGGAACCTCTGTACGAAGGGAACATCGGCTTTGCCGCCCGGGTAATGAAGAACTTC
GGTTTTCACAACATGGTCCT

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLPLTVEPADPSCARFEGIDYVF
VPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLNPNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEY
SGMYGDPAVTRAVSEALSTTRVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK

Sequences:

>Translated_226_residues
MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLPLTVEPADPSCARFEGIDYVF
VPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLNPNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEY
SGMYGDPAVTRAVSEALSTTRVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK
>Mature_226_residues
MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLPLTVEPADPSCARFEGIDYVF
VPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLNPNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEY
SGMYGDPAVTRAVSEALSTTRVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_METLZ (A2SSK1)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030574.1
- ProteinModelPortal:   A2SSK1
- SMR:   A2SSK1
- STRING:   A2SSK1
- GeneID:   4795489
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_1138
- eggNOG:   arNOG18236
- HOGENOM:   HBG313841
- OMA:   TGAHKEW
- ProtClustDB:   PRK04169
- BioCyc:   MLAB410358:MLAB_1138-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 24508; Mature: 24508

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: BINDING 11-11 BINDING 162-162 BINDING 187-187 BINDING 208-208

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLP
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
LTVEPADPSCARFEGIDYVFVPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLN
EEECCCCCCHHHHCCCCEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEYSGMYGDPAVTRAVSEALSTT
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
RVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK
EEEECCCCCCCCHHHHHHHHHCEEEECCHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLP
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
LTVEPADPSCARFEGIDYVFVPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLN
EEECCCCCCHHHHCCCCEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEYSGMYGDPAVTRAVSEALSTT
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
RVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK
EEEECCCCCCCCHHHHHHHHHCEEEECCHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA