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The map label for this gene is yoaA [C]

Identifier: 124485924

GI number: 124485924

Start: 1115463

End: 1117493

Strand: Reverse

Name: yoaA [C]

Synonym: Mlab_1104

Alternate gene names: 124485924

Gene position: 1117493-1115463 (Counterclockwise)

Preceding gene: 124485927

Following gene: 124485923

Centisome position: 61.91

GC content: 53.37

Gene sequence:

>2031_bases
ATGGCAGACACAGCTGACTTTTTTCCCTATCAAACCTACCGGAAAAACCAAAAGGAAATGCTCGAAGAGGTAGAAAAAAC
CGCCGAAGAAAACGGCATCCTCTTAATTGACGCACCGACCGGCAGCGGGAAATCCAGCGTGATCGCAAGTCTCCTTGCTA
AAGCCAACGGACGAAAGATCCTCGTCGCCGTCAGAACCATATCCCAGCTCCAGATCTTCATTCGGGAACTCGACCTCATC
AGGCAGAAAAAACAGCCGACCCTTAAATTCGTTTACCTTATTGGAAAGGGAAACATGTGCCCTCTCGGAGGATACGGGGA
TGTCTACCGAAGATGCGAAGGCGTCAAAGCATTCACCTCGGCACTTATGCAGCAGAGGGCAGACCGCGGTTCATTCGATC
CGGCAACCGACAAACAGATTCTCGAGCAGATCAGAAAGCAGGATCGGGAACATCCTCTCATTTGTCCCTACTTCGTCAAC
AGCCGGGTCTTTGTCCAGAGCGAAGAGGGCGGGCGGCGCATGATCCCTTCCCCGGAACTCAGACGCAAATCCGATATTGC
TCAGAAACAGATCGTCCGACCAAACGAACTTCTGAATTTCGCGGGCAAGGTCTGTCCCTACGACCTCATGCTCTCGGCCG
CCAAGGGAGCTGATGTGATCATCTGTAACTACTATCACCTCTTCAACGACGATATCAGAGAGCAGCTGTACGTCAATCTT
CAGTGCGAGGAGCACAACGTCATGCTCCTCCTTGATGAAGCCCACAACTTAGGCGACGTCATTCAGACGATCCAGAGCAT
TCGGATACGGGACACCGACATCGAAGCCGCGGCAAACGAAGTCGCTTCACTCCGCGATAAGGTCCGCGGTTCCGAAGCGG
TCCGCCATATCCTCCCGAGAATTGCCGAGTTCATCGACGGGCTCCAGCGTTCGAACGAGGCAGAGGACTGGTTTGACCCG
CAGATCTTCAACCGGTTCATCATCAAAGGTTCTCTGTATGGAAAACCCGAGGCGATGCTCGAAGATATCATTTCCATCAA
AGAGGCTATGCGCGAACGCGGCATCGAACGGGGCGACTACCGCGAATCGGCGATCGAAAAACTCTGCGAATTTTTGATCC
GGCTCTACCGCTCTTCCACCGACCCGTCGTTTCTGACCGTTTACACCAAAGACGCCGAGACCATCACGCTTGAGGTCAGA
AACATCGATCCGGCCGATCGGCTCCAAGAGCTCGTCTCCAAACATGCAGCAACCATTCTGATCAGCGGAACGCTGTCGCC
GGTCGATTCCTACAGGAAATACTACTTCGGCAGCATGCCTGTCAAAACCCTCTCGCTTGCCAACTCGTTTCCCAAAGAAA
ACCGCCTGGTTCTTGGGACCCGGGACATCACCACGGCATTTTCCAAACGCCAGAACGCCGAGAACACTCAGGCAATTGTG
GAGTATATTCTTGCCTTTGCCAAACTCCCAGGAAACATCGCGGTCTACTTCCCTTCCTATCAGTTGCAGAACCGTTTTGC
CGAAGCATGCGTAAGCAAGATTCGAAACAAACAGGTATTCATTGAGCCGCGTGAATCAGACGAGGCAAACGAAGCGCTGA
AGGAGTTCATCTCGCTCCCGGGAAAACATAAATCCGGGATACTTTTCGCCGTCTGCGGCGGGAAATGGAGCGAAGGTCTG
GATTACCGGGGCGATCAACTGACCGCGGCCCTCGTGATAGGTCTCCCGCTCGCTCCGTTCACCCCCGTTCGTCGGATGGT
CAACAGTTATTACCGGCGCAAGTTTGGGGCCGAAGGAGAGTTCATCGCCTACACGCTTCCTGCGATCAACAAATCTATGC
AGGCCCTCGGTCGTGTCCTTCGAACCGAAAACGACCGGGGTGTTTTGATTCTCGGCGACCAAAGATTCCTTGAAGGCGAG
ATTTTCGGCGGTTTATCTCCCTGGATGCAGGATGAACTTATGGAATGCGATGTGGACACGGTAAAAAGTAAGCTTGAAAA
GTGGGGACGTGATGCGTCAGGGCGCCTGTAG

Upstream 100 bases:

>100_bases
ATACCTCCACCTTTGCGAGAAGTGCGAGTATCTGATCTTTGGTCTGGGTCGAAAGAGGCATGCTTAATAGATTTGGGTCC
AGACAAATAATACATTACGA

Downstream 100 bases:

>100_bases
TTTCGGACTCTGGAAGGTCGCTGTCGATTATGACGATATGGTAGTCCACCGGGTCAGGTTCATGAGAACGGCACCGGACG
GGCCGGTTCCGATAGAGTTC

Product: queuine tRNA-ribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MADTADFFPYQTYRKNQKEMLEEVEKTAEENGILLIDAPTGSGKSSVIASLLAKANGRKILVAVRTISQLQIFIRELDLI
RQKKQPTLKFVYLIGKGNMCPLGGYGDVYRRCEGVKAFTSALMQQRADRGSFDPATDKQILEQIRKQDREHPLICPYFVN
SRVFVQSEEGGRRMIPSPELRRKSDIAQKQIVRPNELLNFAGKVCPYDLMLSAAKGADVIICNYYHLFNDDIREQLYVNL
QCEEHNVMLLLDEAHNLGDVIQTIQSIRIRDTDIEAAANEVASLRDKVRGSEAVRHILPRIAEFIDGLQRSNEAEDWFDP
QIFNRFIIKGSLYGKPEAMLEDIISIKEAMRERGIERGDYRESAIEKLCEFLIRLYRSSTDPSFLTVYTKDAETITLEVR
NIDPADRLQELVSKHAATILISGTLSPVDSYRKYYFGSMPVKTLSLANSFPKENRLVLGTRDITTAFSKRQNAENTQAIV
EYILAFAKLPGNIAVYFPSYQLQNRFAEACVSKIRNKQVFIEPRESDEANEALKEFISLPGKHKSGILFAVCGGKWSEGL
DYRGDQLTAALVIGLPLAPFTPVRRMVNSYYRRKFGAEGEFIAYTLPAINKSMQALGRVLRTENDRGVLILGDQRFLEGE
IFGGLSPWMQDELMECDVDTVKSKLEKWGRDASGRL

Sequences:

>Translated_676_residues
MADTADFFPYQTYRKNQKEMLEEVEKTAEENGILLIDAPTGSGKSSVIASLLAKANGRKILVAVRTISQLQIFIRELDLI
RQKKQPTLKFVYLIGKGNMCPLGGYGDVYRRCEGVKAFTSALMQQRADRGSFDPATDKQILEQIRKQDREHPLICPYFVN
SRVFVQSEEGGRRMIPSPELRRKSDIAQKQIVRPNELLNFAGKVCPYDLMLSAAKGADVIICNYYHLFNDDIREQLYVNL
QCEEHNVMLLLDEAHNLGDVIQTIQSIRIRDTDIEAAANEVASLRDKVRGSEAVRHILPRIAEFIDGLQRSNEAEDWFDP
QIFNRFIIKGSLYGKPEAMLEDIISIKEAMRERGIERGDYRESAIEKLCEFLIRLYRSSTDPSFLTVYTKDAETITLEVR
NIDPADRLQELVSKHAATILISGTLSPVDSYRKYYFGSMPVKTLSLANSFPKENRLVLGTRDITTAFSKRQNAENTQAIV
EYILAFAKLPGNIAVYFPSYQLQNRFAEACVSKIRNKQVFIEPRESDEANEALKEFISLPGKHKSGILFAVCGGKWSEGL
DYRGDQLTAALVIGLPLAPFTPVRRMVNSYYRRKFGAEGEFIAYTLPAINKSMQALGRVLRTENDRGVLILGDQRFLEGE
IFGGLSPWMQDELMECDVDTVKSKLEKWGRDASGRL
>Mature_675_residues
ADTADFFPYQTYRKNQKEMLEEVEKTAEENGILLIDAPTGSGKSSVIASLLAKANGRKILVAVRTISQLQIFIRELDLIR
QKKQPTLKFVYLIGKGNMCPLGGYGDVYRRCEGVKAFTSALMQQRADRGSFDPATDKQILEQIRKQDREHPLICPYFVNS
RVFVQSEEGGRRMIPSPELRRKSDIAQKQIVRPNELLNFAGKVCPYDLMLSAAKGADVIICNYYHLFNDDIREQLYVNLQ
CEEHNVMLLLDEAHNLGDVIQTIQSIRIRDTDIEAAANEVASLRDKVRGSEAVRHILPRIAEFIDGLQRSNEAEDWFDPQ
IFNRFIIKGSLYGKPEAMLEDIISIKEAMRERGIERGDYRESAIEKLCEFLIRLYRSSTDPSFLTVYTKDAETITLEVRN
IDPADRLQELVSKHAATILISGTLSPVDSYRKYYFGSMPVKTLSLANSFPKENRLVLGTRDITTAFSKRQNAENTQAIVE
YILAFAKLPGNIAVYFPSYQLQNRFAEACVSKIRNKQVFIEPRESDEANEALKEFISLPGKHKSGILFAVCGGKWSEGLD
YRGDQLTAALVIGLPLAPFTPVRRMVNSYYRRKFGAEGEFIAYTLPAINKSMQALGRVLRTENDRGVLILGDQRFLEGEI
FGGLSPWMQDELMECDVDTVKSKLEKWGRDASGRL

Specific function: Unknown

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI301897118, Length=542, Percent_Identity=24.169741697417, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI15834617, Length=757, Percent_Identity=22.5891677675033, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI91984775, Length=547, Percent_Identity=22.4862888482633, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI7706541, Length=547, Percent_Identity=22.4862888482633, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994598, Length=520, Percent_Identity=23.0769230769231, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17554258, Length=282, Percent_Identity=28.0141843971631, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506821, Length=575, Percent_Identity=21.7391304347826, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507137, Length=294, Percent_Identity=25.1700680272109, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325249, Length=508, Percent_Identity=22.8346456692913, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321019, Length=280, Percent_Identity=26.0714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551134, Length=743, Percent_Identity=22.6110363391655, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363902, Length=727, Percent_Identity=22.5584594222834, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17137232, Length=727, Percent_Identity=22.5584594222834, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24639946, Length=271, Percent_Identity=26.9372693726937, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18543219, Length=315, Percent_Identity=24.7619047619048, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76618; Mature: 76487

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTADFFPYQTYRKNQKEMLEEVEKTAEENGILLIDAPTGSGKSSVIASLLAKANGRKI
CCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCEE
LVAVRTISQLQIFIRELDLIRQKKQPTLKFVYLIGKGNMCPLGGYGDVYRRCEGVKAFTS
EEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCHHHHHH
ALMQQRADRGSFDPATDKQILEQIRKQDREHPLICPYFVNSRVFVQSEEGGRRMIPSPEL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCHH
RRKSDIAQKQIVRPNELLNFAGKVCPYDLMLSAAKGADVIICNYYHLFNDDIREQLYVNL
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEHHHHCHHHHHHEEEEE
QCEEHNVMLLLDEAHNLGDVIQTIQSIRIRDTDIEAAANEVASLRDKVRGSEAVRHILPR
EECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
IAEFIDGLQRSNEAEDWFDPQIFNRFIIKGSLYGKPEAMLEDIISIKEAMRERGIERGDY
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
RESAIEKLCEFLIRLYRSSTDPSFLTVYTKDAETITLEVRNIDPADRLQELVSKHAATIL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCEEEE
ISGTLSPVDSYRKYYFGSMPVKTLSLANSFPKENRLVLGTRDITTAFSKRQNAENTQAIV
EECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHH
EYILAFAKLPGNIAVYFPSYQLQNRFAEACVSKIRNKQVFIEPRESDEANEALKEFISLP
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCC
GKHKSGILFAVCGGKWSEGLDYRGDQLTAALVIGLPLAPFTPVRRMVNSYYRRKFGAEGE
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCC
FIAYTLPAINKSMQALGRVLRTENDRGVLILGDQRFLEGEIFGGLSPWMQDELMECDVDT
EEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCHHCCCCCHHHHHHHHHCCHHH
VKSKLEKWGRDASGRL
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ADTADFFPYQTYRKNQKEMLEEVEKTAEENGILLIDAPTGSGKSSVIASLLAKANGRKI
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCEE
LVAVRTISQLQIFIRELDLIRQKKQPTLKFVYLIGKGNMCPLGGYGDVYRRCEGVKAFTS
EEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCHHHHHH
ALMQQRADRGSFDPATDKQILEQIRKQDREHPLICPYFVNSRVFVQSEEGGRRMIPSPEL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCHH
RRKSDIAQKQIVRPNELLNFAGKVCPYDLMLSAAKGADVIICNYYHLFNDDIREQLYVNL
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEHHHHCHHHHHHEEEEE
QCEEHNVMLLLDEAHNLGDVIQTIQSIRIRDTDIEAAANEVASLRDKVRGSEAVRHILPR
EECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHH
IAEFIDGLQRSNEAEDWFDPQIFNRFIIKGSLYGKPEAMLEDIISIKEAMRERGIERGDY
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
RESAIEKLCEFLIRLYRSSTDPSFLTVYTKDAETITLEVRNIDPADRLQELVSKHAATIL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCEEEE
ISGTLSPVDSYRKYYFGSMPVKTLSLANSFPKENRLVLGTRDITTAFSKRQNAENTQAIV
EECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHH
EYILAFAKLPGNIAVYFPSYQLQNRFAEACVSKIRNKQVFIEPRESDEANEALKEFISLP
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCC
GKHKSGILFAVCGGKWSEGLDYRGDQLTAALVIGLPLAPFTPVRRMVNSYYRRKFGAEGE
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCC
FIAYTLPAINKSMQALGRVLRTENDRGVLILGDQRFLEGEIFGGLSPWMQDELMECDVDT
EEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCHHCCCCCHHHHHHHHHCCHHH
VKSKLEKWGRDASGRL
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]