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The map label for this gene is fecD [C]

Identifier: 124485909

GI number: 124485909

Start: 1102567

End: 1103634

Strand: Reverse

Name: fecD [C]

Synonym: Mlab_1089

Alternate gene names: 124485909

Gene position: 1103634-1102567 (Counterclockwise)

Preceding gene: 124485910

Following gene: 124485908

Centisome position: 61.14

GC content: 47.38

Gene sequence:

>1068_bases
ATGACAAAAGAAGAGAAAAAACCAACGGACTACAAAGCCTACGTCGGCAGAAAAGTAACGATAATTGTAATCGGAATCAT
TGCAACTGTCGTTATGTTTCTCGTATCGGTTTCGGTAGGTGCTGTATCTATTCCAATTCCCGATATTATCACAACGATTT
TTGGCGGCGGCGGCACAAGTCTTTATGAAAGAATTATCTGGAATATCAGGATTCCTCAGGCTTTGACGGCTATTGTGGCC
GGCGCTGGACTAGCAATTGCCGGCGTTTCCATGCAGTCCGTTTTGCGTAATCCGCTTGCCTCTCCGTTTACCCTTGGTTT
ATCCAGTGCCGCTGCCTTTGGAGCTGCTGTCGGTATTCTGCTTTTTGGAGCAGGAACGACTGGAAGCAGCATCGCCGATG
CAGTTGTAATTAACAACCCGTATCTGACTACAATCTCGGCGTTCGTCTTCTCTATTCTGACAACAGTAATTATTCTGTTC
ATTGCAAAGATTCGCTCTGCAACGCCCGAAACGATGATTCTGGCAGGTGTTGCCATAAGTTCGCTCTTTAGCGCCGGATT
AATGGCAATTCAGTACTTCGTTGATGACACCCGTCTTGCCTCAATCGTTTTCTGGCAGTTTGGAGATGTTGCAAGAGCAA
GCTGGACAGAGTTAGGACTGATTACGCTGATGACCGTCATTTGCTTTATCTATTTCATCTATAAACGCTGGGATTATAAC
TCGATAGATGCCGGAGAAGAAACTGCAAAAGGTCTGGGTGTCAATGTTGAGAGGACACGCCTCCTTGGTATGATCGCTGC
ATCCTTGATCAGCGCTGTAATCGTGGCATTTCTTGGGATCATCGGCTTTGTCGGTCTCGTTTGTCCGCATATGATGCGGC
GTGTCATCGGCGACGATCACCGATTTTTGATTCCGGCAAGTTTTGTCTGCGGAGCAGTGCTTTTACTTGTTTCCGATACT
ATCGCAAGAACCTTGATCGCTCCGCATGTTTTGCCCGTAGCAGTTTTGACTGCATTCCTCGGGGCGCCCGTGTTCCTGTA
TCTCATTATCAGGGGGAGACGAACATGA

Upstream 100 bases:

>100_bases
TATTCTGACAGTTCAGGGACTGGAAGCATTGGATCAGACACCAGTTGTTGACATCAAACCTTATTCAGAAGGAATCGATA
CGCCGCGAAATGGATAAAAA

Downstream 100 bases:

>100_bases
CTGACGACATATCTCACGAAGAGCACAACCACGATGAAAAAATGCATGTACACCCTCATGTTCATTCAGAAGGATATGTC
CATACGCATGAACATCTTCA

Product: hypothetical protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTKEEKKPTDYKAYVGRKVTIIVIGIIATVVMFLVSVSVGAVSIPIPDIITTIFGGGGTSLYERIIWNIRIPQALTAIVA
GAGLAIAGVSMQSVLRNPLASPFTLGLSSAAAFGAAVGILLFGAGTTGSSIADAVVINNPYLTTISAFVFSILTTVIILF
IAKIRSATPETMILAGVAISSLFSAGLMAIQYFVDDTRLASIVFWQFGDVARASWTELGLITLMTVICFIYFIYKRWDYN
SIDAGEETAKGLGVNVERTRLLGMIAASLISAVIVAFLGIIGFVGLVCPHMMRRVIGDDHRFLIPASFVCGAVLLLVSDT
IARTLIAPHVLPVAVLTAFLGAPVFLYLIIRGRRT

Sequences:

>Translated_355_residues
MTKEEKKPTDYKAYVGRKVTIIVIGIIATVVMFLVSVSVGAVSIPIPDIITTIFGGGGTSLYERIIWNIRIPQALTAIVA
GAGLAIAGVSMQSVLRNPLASPFTLGLSSAAAFGAAVGILLFGAGTTGSSIADAVVINNPYLTTISAFVFSILTTVIILF
IAKIRSATPETMILAGVAISSLFSAGLMAIQYFVDDTRLASIVFWQFGDVARASWTELGLITLMTVICFIYFIYKRWDYN
SIDAGEETAKGLGVNVERTRLLGMIAASLISAVIVAFLGIIGFVGLVCPHMMRRVIGDDHRFLIPASFVCGAVLLLVSDT
IARTLIAPHVLPVAVLTAFLGAPVFLYLIIRGRRT
>Mature_354_residues
TKEEKKPTDYKAYVGRKVTIIVIGIIATVVMFLVSVSVGAVSIPIPDIITTIFGGGGTSLYERIIWNIRIPQALTAIVAG
AGLAIAGVSMQSVLRNPLASPFTLGLSSAAAFGAAVGILLFGAGTTGSSIADAVVINNPYLTTISAFVFSILTTVIILFI
AKIRSATPETMILAGVAISSLFSAGLMAIQYFVDDTRLASIVFWQFGDVARASWTELGLITLMTVICFIYFIYKRWDYNS
IDAGEETAKGLGVNVERTRLLGMIAASLISAVIVAFLGIIGFVGLVCPHMMRRVIGDDHRFLIPASFVCGAVLLLVSDTI
ARTLIAPHVLPVAVLTAFLGAPVFLYLIIRGRRT

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=337, Percent_Identity=32.9376854599407, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788004, Length=296, Percent_Identity=34.4594594594595, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790741, Length=328, Percent_Identity=28.9634146341463, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786805, Length=321, Percent_Identity=31.1526479750779, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786347, Length=302, Percent_Identity=31.1258278145695, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786804, Length=348, Percent_Identity=28.735632183908, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37753; Mature: 37622

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEEKKPTDYKAYVGRKVTIIVIGIIATVVMFLVSVSVGAVSIPIPDIITTIFGGGGTS
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHCCCCHH
LYERIIWNIRIPQALTAIVAGAGLAIAGVSMQSVLRNPLASPFTLGLSSAAAFGAAVGIL
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LFGAGTTGSSIADAVVINNPYLTTISAFVFSILTTVIILFIAKIRSATPETMILAGVAIS
HEECCCCCCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SLFSAGLMAIQYFVDDTRLASIVFWQFGDVARASWTELGLITLMTVICFIYFIYKRWDYN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIDAGEETAKGLGVNVERTRLLGMIAASLISAVIVAFLGIIGFVGLVCPHMMRRVIGDDH
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RFLIPASFVCGAVLLLVSDTIARTLIAPHVLPVAVLTAFLGAPVFLYLIIRGRRT
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKEEKKPTDYKAYVGRKVTIIVIGIIATVVMFLVSVSVGAVSIPIPDIITTIFGGGGTS
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHCCCCHH
LYERIIWNIRIPQALTAIVAGAGLAIAGVSMQSVLRNPLASPFTLGLSSAAAFGAAVGIL
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LFGAGTTGSSIADAVVINNPYLTTISAFVFSILTTVIILFIAKIRSATPETMILAGVAIS
HEECCCCCCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SLFSAGLMAIQYFVDDTRLASIVFWQFGDVARASWTELGLITLMTVICFIYFIYKRWDYN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIDAGEETAKGLGVNVERTRLLGMIAASLISAVIVAFLGIIGFVGLVCPHMMRRVIGDDH
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RFLIPASFVCGAVLLLVSDTIARTLIAPHVLPVAVLTAFLGAPVFLYLIIRGRRT
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]