Click here to switch to the map view.

The map label for this gene is fecD [C]

Identifier: 124485863

GI number: 124485863

Start: 1053355

End: 1054359

Strand: Reverse

Name: fecD [C]

Synonym: Mlab_1043

Alternate gene names: 124485863

Gene position: 1054359-1053355 (Counterclockwise)

Preceding gene: 124485864

Following gene: 124485862

Centisome position: 58.41

GC content: 43.08

Gene sequence:

>1005_bases
ATGAAAACAGTCTCAAAAAAATCATTTTTTATTTTTCTATTTTTTCTTCCGATAGCAGTCGCTTGTCTTGCTCTCTGCAT
TGGAAGATACTGGATCAACCCCATTGATGTCTATGGAGCATTTTTGGCATTTTTTGGATATCCCGTTGAAACGACCATCC
AGTCAGTTGTTATCAACCTTCGGCTTCCGCGAATCCTTCTCGCTCTCTTTGTAGGAGCAGGACTTGCCGTTGCCGGAGCA
GCGTTTCAGTCAACATTTTCAAACCCATTGGCCTCACCGGACATCATCGGTGTTTCGTCGGGAGCTGCCTTTGGCGCAGC
ACTTGGTCTTTTGCTCTTTGAAAATATGTTCATCGTTCAGATTCTTGCAATCATTTTTGGTCTTGCGGCGATTGGAATTA
CCTTTACGTTAAGTAAAGCGGCTAAAACTGATTCGATCCTCATGATAGTGCTTGCCGGAATCATTGTCTCCGGATTTTTT
ACAGCGATGATTTCATTGGTAAAATATACCGCCGACCCTCTGCTGAAACTTCCTGAAATTACTTTTTGGCTCATGGGCAG
TTTGGCAGGGGCGAATTATGAAAAAATTCTGATTGCAGCACCGCTGTTACTCCTTGGTATCATCATTATCTGGATAATGA
AATGGCGTTTAAACATCCTTGCGTTAAGTGAGGAGGAAATCCAATCATGTGGAATCAATCCAAAACGTACCCGGTGGACA
ATTATCATAGCTGCAACATTGATTGTCGCAGCGACAGTATCACTTTGCGGACAAATTGGGTGGGTTGGATTAGTAATACC
TCATGTTGCCCGAATGCTGGTTGGGTCAGATAATCGTTATGTTATTCCAGCAAGCATCAGCATTGGAGCCTGCTATCTTC
TGATAATCGATACACTCTGCAGAACACTATCGCCCTCGGAAATCCCGTTATCTATTATGACGGCGTTGATTGGAGCTCCA
TTATTTGCATATCTCTTTCTTAAAAAAGCGAGGTCATGGCTATGA

Upstream 100 bases:

>100_bases
ACCTCATACTTCTTCAAAGAATTTTTCAATTATACTGCAACAGATGAAGACATCAAAGGATTCCTGAATCCCGAATACAT
TGCAGTAAGACTCCACTAAG

Downstream 100 bases:

>100_bases
AACTAACTATTCAAAATGGCGGCTTTGGTTATCATGATGAGTATTTATTTAAAAACATTAATTTCACGGTGAATGACCAA
GAGGTCTTCGCAATTCTCGG

Product: hypothetical protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKTVSKKSFFIFLFFLPIAVACLALCIGRYWINPIDVYGAFLAFFGYPVETTIQSVVINLRLPRILLALFVGAGLAVAGA
AFQSTFSNPLASPDIIGVSSGAAFGAALGLLLFENMFIVQILAIIFGLAAIGITFTLSKAAKTDSILMIVLAGIIVSGFF
TAMISLVKYTADPLLKLPEITFWLMGSLAGANYEKILIAAPLLLLGIIIIWIMKWRLNILALSEEEIQSCGINPKRTRWT
IIIAATLIVAATVSLCGQIGWVGLVIPHVARMLVGSDNRYVIPASISIGACYLLIIDTLCRTLSPSEIPLSIMTALIGAP
LFAYLFLKKARSWL

Sequences:

>Translated_334_residues
MKTVSKKSFFIFLFFLPIAVACLALCIGRYWINPIDVYGAFLAFFGYPVETTIQSVVINLRLPRILLALFVGAGLAVAGA
AFQSTFSNPLASPDIIGVSSGAAFGAALGLLLFENMFIVQILAIIFGLAAIGITFTLSKAAKTDSILMIVLAGIIVSGFF
TAMISLVKYTADPLLKLPEITFWLMGSLAGANYEKILIAAPLLLLGIIIIWIMKWRLNILALSEEEIQSCGINPKRTRWT
IIIAATLIVAATVSLCGQIGWVGLVIPHVARMLVGSDNRYVIPASISIGACYLLIIDTLCRTLSPSEIPLSIMTALIGAP
LFAYLFLKKARSWL
>Mature_334_residues
MKTVSKKSFFIFLFFLPIAVACLALCIGRYWINPIDVYGAFLAFFGYPVETTIQSVVINLRLPRILLALFVGAGLAVAGA
AFQSTFSNPLASPDIIGVSSGAAFGAALGLLLFENMFIVQILAIIFGLAAIGITFTLSKAAKTDSILMIVLAGIIVSGFF
TAMISLVKYTADPLLKLPEITFWLMGSLAGANYEKILIAAPLLLLGIIIIWIMKWRLNILALSEEEIQSCGINPKRTRWT
IIIAATLIVAATVSLCGQIGWVGLVIPHVARMLVGSDNRYVIPASISIGACYLLIIDTLCRTLSPSEIPLSIMTALIGAP
LFAYLFLKKARSWL

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=35.3571428571429, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1790741, Length=328, Percent_Identity=31.0975609756098, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788004, Length=310, Percent_Identity=31.9354838709677, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786805, Length=294, Percent_Identity=29.9319727891156, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786347, Length=273, Percent_Identity=31.5018315018315, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786804, Length=301, Percent_Identity=26.9102990033223, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36024; Mature: 36024

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVSKKSFFIFLFFLPIAVACLALCIGRYWINPIDVYGAFLAFFGYPVETTIQSVVINL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RLPRILLALFVGAGLAVAGAAFQSTFSNPLASPDIIGVSSGAAFGAALGLLLFENMFIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ILAIIFGLAAIGITFTLSKAAKTDSILMIVLAGIIVSGFFTAMISLVKYTADPLLKLPEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHH
TFWLMGSLAGANYEKILIAAPLLLLGIIIIWIMKWRLNILALSEEEIQSCGINPKRTRWT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCCCHHHH
IIIAATLIVAATVSLCGQIGWVGLVIPHVARMLVGSDNRYVIPASISIGACYLLIIDTLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
RTLSPSEIPLSIMTALIGAPLFAYLFLKKARSWL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTVSKKSFFIFLFFLPIAVACLALCIGRYWINPIDVYGAFLAFFGYPVETTIQSVVINL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RLPRILLALFVGAGLAVAGAAFQSTFSNPLASPDIIGVSSGAAFGAALGLLLFENMFIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ILAIIFGLAAIGITFTLSKAAKTDSILMIVLAGIIVSGFFTAMISLVKYTADPLLKLPEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHH
TFWLMGSLAGANYEKILIAAPLLLLGIIIIWIMKWRLNILALSEEEIQSCGINPKRTRWT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCCCHHHH
IIIAATLIVAATVSLCGQIGWVGLVIPHVARMLVGSDNRYVIPASISIGACYLLIIDTLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
RTLSPSEIPLSIMTALIGAPLFAYLFLKKARSWL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]