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The map label for this gene is panE [C]

Identifier: 124485202

GI number: 124485202

Start: 352474

End: 353382

Strand: Reverse

Name: panE [C]

Synonym: Mlab_0375

Alternate gene names: 124485202

Gene position: 353382-352474 (Counterclockwise)

Preceding gene: 124485209

Following gene: 124485201

Centisome position: 19.58

GC content: 48.07

Gene sequence:

>909_bases
ATGAGGATATTAATACTTGGTGCCGGAGCAGTAGGGCTGTCAGTCGCCGCAAAATTATCGAAATATGCCGAAGTTTTTGC
AGTATGCCGGGAAAGATGCAGTACGTCTATCGAAAAGGATGGCTTTTTTCTAACAGGGATCTGGGGGACGGAAACATTCC
GGTTTCCCTGCGGAGTAACTCCCCCGGAAGGGCCCTGGGATTATATCATTATATCCACCAAAGCTGCCGCCACACGCGAA
ATATGTGAAAAATATAATCATCTGTTCGGTGAGGCCGAGGTCGTGAGTCTCCAGAACGGAATCGGAAATGAAGAGGTCAT
TGCCGAATATACCGACCATGTGATCGGCGCAATGATTATTACCGGATTTGAATGGAAAGCAGACAATGCGGTGTTCGTAT
CAGTCGACGGCGGAGCCACAGTCTTTGGAAGATATACGGGAGGAGCTGATCGAAAAGCGGAACTCCTGTCTGATCTCTTC
AACAAAGCAGGCATGCGGGCGAGCGCCACGGATAATATCAAAGGGACCATCTGGTCAAAAGCATTGTACAGCTGCTCGCT
GAATCCTCTTGGGGCAGTTATGGAATGCCCTTACGGAGATCTCCTCAGAGAACCCGCATGGAATATCATTATTAACATAG
TGCATGAAGCGTTCGAAGTGGCACGCGCAGAAAATATCTCACTTGTACAAAAAACAGCGAATGAATATCTTGAGTTCCTG
AAGACAGCGAAGATCCCCCCAACGGCCGCACATTTTTCCTCAATGTATCAGGACATAGCTGCCGGCCGCAAAACCGAGGT
TGACTTTATCAATGGAGCCATAGTTTCACTTGGCAGGAGACACGGCATCCCAACTCCCGTGAATGAAACGATCGTCAATT
TAACTCACTTCAAAGAGGAGCTTTCATGA

Upstream 100 bases:

>100_bases
TTACACCAAAAATTCACAAGTTTTGCATCCGACATACGGGCTGCCCACATCAGGAAAACCCTGCTTTTAATGTGGTGAAG
AGACAATATAATAAGAACAA

Downstream 100 bases:

>100_bases
CGGCAAAACGATCCGCGATGATCCTTGCAGGCGGTGAGGCACGAAGAGTAAACGGACGCGAAAAGTATTTGTTTTCTTAC
CAAGGCTGCTCATTTATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRILILGAGAVGLSVAAKLSKYAEVFAVCRERCSTSIEKDGFFLTGIWGTETFRFPCGVTPPEGPWDYIIISTKAAATRE
ICEKYNHLFGEAEVVSLQNGIGNEEVIAEYTDHVIGAMIITGFEWKADNAVFVSVDGGATVFGRYTGGADRKAELLSDLF
NKAGMRASATDNIKGTIWSKALYSCSLNPLGAVMECPYGDLLREPAWNIIINIVHEAFEVARAENISLVQKTANEYLEFL
KTAKIPPTAAHFSSMYQDIAAGRKTEVDFINGAIVSLGRRHGIPTPVNETIVNLTHFKEELS

Sequences:

>Translated_302_residues
MRILILGAGAVGLSVAAKLSKYAEVFAVCRERCSTSIEKDGFFLTGIWGTETFRFPCGVTPPEGPWDYIIISTKAAATRE
ICEKYNHLFGEAEVVSLQNGIGNEEVIAEYTDHVIGAMIITGFEWKADNAVFVSVDGGATVFGRYTGGADRKAELLSDLF
NKAGMRASATDNIKGTIWSKALYSCSLNPLGAVMECPYGDLLREPAWNIIINIVHEAFEVARAENISLVQKTANEYLEFL
KTAKIPPTAAHFSSMYQDIAAGRKTEVDFINGAIVSLGRRHGIPTPVNETIVNLTHFKEELS
>Mature_302_residues
MRILILGAGAVGLSVAAKLSKYAEVFAVCRERCSTSIEKDGFFLTGIWGTETFRFPCGVTPPEGPWDYIIISTKAAATRE
ICEKYNHLFGEAEVVSLQNGIGNEEVIAEYTDHVIGAMIITGFEWKADNAVFVSVDGGATVFGRYTGGADRKAELLSDLF
NKAGMRASATDNIKGTIWSKALYSCSLNPLGAVMECPYGDLLREPAWNIIINIVHEAFEVARAENISLVQKTANEYLEFL
KTAKIPPTAAHFSSMYQDIAAGRKTEVDFINGAIVSLGRRHGIPTPVNETIVNLTHFKEELS

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=307, Percent_Identity=27.6872964169381, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32952; Mature: 32952

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILILGAGAVGLSVAAKLSKYAEVFAVCRERCSTSIEKDGFFLTGIWGTETFRFPCGVT
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCC
PPEGPWDYIIISTKAAATREICEKYNHLFGEAEVVSLQNGIGNEEVIAEYTDHVIGAMII
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
TGFEWKADNAVFVSVDGGATVFGRYTGGADRKAELLSDLFNKAGMRASATDNIKGTIWSK
CCCEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ALYSCSLNPLGAVMECPYGDLLREPAWNIIINIVHEAFEVARAENISLVQKTANEYLEFL
HHHHCCCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KTAKIPPTAAHFSSMYQDIAAGRKTEVDFINGAIVSLGRRHGIPTPVNETIVNLTHFKEE
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LS
CC
>Mature Secondary Structure
MRILILGAGAVGLSVAAKLSKYAEVFAVCRERCSTSIEKDGFFLTGIWGTETFRFPCGVT
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCCCC
PPEGPWDYIIISTKAAATREICEKYNHLFGEAEVVSLQNGIGNEEVIAEYTDHVIGAMII
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
TGFEWKADNAVFVSVDGGATVFGRYTGGADRKAELLSDLFNKAGMRASATDNIKGTIWSK
CCCEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ALYSCSLNPLGAVMECPYGDLLREPAWNIIINIVHEAFEVARAENISLVQKTANEYLEFL
HHHHCCCCCCCHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KTAKIPPTAAHFSSMYQDIAAGRKTEVDFINGAIVSLGRRHGIPTPVNETIVNLTHFKEE
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]