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The map label for this gene is gph [C]

Identifier: 124485091

GI number: 124485091

Start: 246910

End: 247545

Strand: Reverse

Name: gph [C]

Synonym: Mlab_0264

Alternate gene names: 124485091

Gene position: 247545-246910 (Counterclockwise)

Preceding gene: 124485092

Following gene: 124485078

Centisome position: 13.71

GC content: 50.47

Gene sequence:

>636_bases
ATGAACCTTCCGCGTGCAGTAATCTTCGACATGGATAACACGCTGCACGATCTGCGTCGGGCACGCCATTGTGCTGCCGA
TGCTTTAATGGCATACTGCGGGATTTTCGGCGACCTGCATATGTATTCTCTGAACAAAAATCCCCCTACTCTGATCGAAG
ACGCCGTTACCCAATATCTGGCAGACGGAGTGGACGGCGATTTCGAGGAGTGCACCTGGCTTTATCATACGCTGGAACTT
GCCTGTATCTCTCCATTCGAAGGGATCGAGGAGATGCTGAGCGATTTAAAATCGGAAGGGGTCCGCCTGGCCGTCATCTC
AAATGCGGACCGACCCGATATGGAAAAACGCATGAAGGCTCTTGGCTATGAACAGTATTTCGAACTGGTCGTCACACCCG
AAACATTCGGTGTAAAAAAACCGAACCCTGAGGTTTATCAGAAAACGCTTGAAGCACTTGGTGTTTCTCCCGAAGAGACA
GTAATGATCGGGGACAAAAAGGACCGGGATGTACGGCCGCCGCGTGAGCTGGGTATCAAAGGAGTGCATGCGACCTTCGG
CTCGGTTGACAAACGGGATAAAATATGTGCTGTCGATTCACCGGCCGAGTTTCTCGAACTCATAAAAAAAAGTTAG

Upstream 100 bases:

>100_bases
AAAGCAATCAACGATTATCTGGTAAAGTCCGGCAGAGAACCGTGGGGAGATGAAGAATGCAGCTCCTGCGGACATGACTG
TGATACGTGTGAACTCTGAG

Downstream 100 bases:

>100_bases
GCGATCTTTGAAAGAGCACCGGTTTTCAGATCATAATACAATCCATGCAGATTCAGACAGCCTTTTTCTTCAGCCATCGA
AACAAGCGGATATGATCTGA

Product: hypothetical protein

Products: Glycolate; Phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNLPRAVIFDMDNTLHDLRRARHCAADALMAYCGIFGDLHMYSLNKNPPTLIEDAVTQYLADGVDGDFEECTWLYHTLEL
ACISPFEGIEEMLSDLKSEGVRLAVISNADRPDMEKRMKALGYEQYFELVVTPETFGVKKPNPEVYQKTLEALGVSPEET
VMIGDKKDRDVRPPRELGIKGVHATFGSVDKRDKICAVDSPAEFLELIKKS

Sequences:

>Translated_211_residues
MNLPRAVIFDMDNTLHDLRRARHCAADALMAYCGIFGDLHMYSLNKNPPTLIEDAVTQYLADGVDGDFEECTWLYHTLEL
ACISPFEGIEEMLSDLKSEGVRLAVISNADRPDMEKRMKALGYEQYFELVVTPETFGVKKPNPEVYQKTLEALGVSPEET
VMIGDKKDRDVRPPRELGIKGVHATFGSVDKRDKICAVDSPAEFLELIKKS
>Mature_211_residues
MNLPRAVIFDMDNTLHDLRRARHCAADALMAYCGIFGDLHMYSLNKNPPTLIEDAVTQYLADGVDGDFEECTWLYHTLEL
ACISPFEGIEEMLSDLKSEGVRLAVISNADRPDMEKRMKALGYEQYFELVVTPETFGVKKPNPEVYQKTLEALGVSPEET
VMIGDKKDRDVRPPRELGIKGVHATFGSVDKRDKICAVDSPAEFLELIKKS

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR011950
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.18 [C]

Molecular weight: Translated: 23715; Mature: 23715

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPRAVIFDMDNTLHDLRRARHCAADALMAYCGIFGDLHMYSLNKNPPTLIEDAVTQYL
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHH
ADGVDGDFEECTWLYHTLELACISPFEGIEEMLSDLKSEGVRLAVISNADRPDMEKRMKA
HCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
LGYEQYFELVVTPETFGVKKPNPEVYQKTLEALGVSPEETVMIGDKKDRDVRPPRELGIK
HCHHHHHHEEECCHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCC
GVHATFGSVDKRDKICAVDSPAEFLELIKKS
CHHHHHCCCCCCCCEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MNLPRAVIFDMDNTLHDLRRARHCAADALMAYCGIFGDLHMYSLNKNPPTLIEDAVTQYL
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHH
ADGVDGDFEECTWLYHTLELACISPFEGIEEMLSDLKSEGVRLAVISNADRPDMEKRMKA
HCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
LGYEQYFELVVTPETFGVKKPNPEVYQKTLEALGVSPEETVMIGDKKDRDVRPPRELGIK
HCHHHHHHEEECCHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCC
GVHATFGSVDKRDKICAVDSPAEFLELIKKS
CHHHHHCCCCCCCCEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.57 {phosphoglycolate}} [C]

Substrates: D-Glycerate 2-phosphatelyc; H2O [C]

Specific reaction: D-Glycerate 2-phosphatelyc + H2O --> Glycolate + Phosphate [C]

General reaction: Additional information:

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]