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The map label for this gene is xylR [H]

Identifier: 124266155

GI number: 124266155

Start: 1020469

End: 1022340

Strand: Reverse

Name: xylR [H]

Synonym: Mpe_A0962

Alternate gene names: 124266155

Gene position: 1022340-1020469 (Counterclockwise)

Preceding gene: 124266170

Following gene: 124266139

Centisome position: 25.28

GC content: 69.34

Gene sequence:

>1872_bases
ATGAGCAATCCTCTCCATTCGCATGCGCACGGGATCACGTCGATGAACGCTTCACCTGCACCGAACGCCGCCGACTTTCT
CCACGCGCATTACCTGGCCAGTCGCAGCGACCCGTCGGCCACGGAGCTCCGGCCCACGCACCGCGAGTTGGCGGAGTGGC
TGACCTTCGACCCGGACACCGGGCGCATCTGGCTCGACGACGAGCGCATGGTGATGCTGAACCACCAGACGCTCGGCTCG
CTGCGCAGCGAACTGATCCAGGGCGTCGGTGTGGAGCGGGCGCGCGGCATCCTCACCCGCAGCGGCTACATCGCCGGCAT
GCGCGACGCGCGCTTCGTGGCCTCGCACTGGCCCAAGGAAGACCCGGTCGGCAAGCTGCTGGCCGGCACGCGCCTGTTCG
GCCTGCAGGGCCTCGCCCGTGTCGAGGCGGTGCACTTCGACTACGACCCCGAGCGCATCGCCTTCAGCGGCGAGTTCTTC
TGGCATCACTCGCTGGAGGACGACGAACACATCAACGCCTTCGGCGTCGGCACCGACGCGGGCTGCTGGCTGCCGATCGG
CTACGCCAACGGCTACGTCTCCACGCTGCTTGGCACGTCGATCATCTTCCGCGAGCTCGAGTGCCGCTCGACCGGTGCCT
CGGTCTGCCGCGTGATCGGCAAGGCCGCCCGCGACTGGGACAACGTGGAGGAAGACCTGCGCTACATGCAGGCCGAGGGC
TTCGTCGGCGAGCGCCCGGGTCCGGAACCGACGCCGCGCGACGGTCCGCGCCTCGGCGTGCACGACGCCGCGGCGGATGC
GGCGCCGCGCATGGTGGGCGTCTCGTCGAGCTTCAATGCCGCCTGCCACTCGCTGCGCAAGGTGGCCACCACCACCGCGA
CGGTCCTGTTCTTCGGCGAGTCCGGGGTCGGCAAGGAGCTGTTCGCCAAGATGCTGCACGAGATCAGCGAGCGACGCGAC
GGGCCCTTCGTGTCGGTCAACTGCGCGGCGATCCCGGAGAACCTTGTCGAGGCCGAGCTGTTCGGCGTCGAGCGCGGCGC
CTACACCGGCGCCCACGCGTCACGGCCGGGCCGCTTCGAGCGCTCGCACCGGGGCACGCTGTTCCTCGACGAGATCTCGT
CGCTGAGCCTGGTCGCGCAGAGCAAGCTGCTGCGCGCGCTGCAGGAGAGCGAGGTCGAGCGGGTCGGTGGCACCCGCCCG
ATCCGGCTCGACCTGCGCGTGGTGGCCGCGTGCAACGTCGACCTGCGCGAGGAAGTCCGGCAGGGGCGCTTCCGCGAAGA
CCTGTTCTTCAGGCTCAACGTCTACCCGATCCACCTGCCGCCGCTGCGGGCCCGCAGCGAGGACGTGCCTCTGCTGATGA
CGCACTTCCTCAAGCTCTACGGTGCCCGCTACGGCCGGCAGATCCACGGCTTCACGCAGCGCGCGATGCGCGCGATGCTG
ACCTACACCTTCCCCGGCAACGTGCGCGAACTGCAGAACATGATCGAGCGGGCCGTGATTGCCGCCAGCGACGAGCCGCA
GATCGATACCGTGCACCTGTTCCGCGACGAGCTGTTCAACGCGAAGTCGACCTTCGCCGTCGGCGATCAAGGCCGATTGG
CCGACACCGAGGGGTCGGCGCCCTCCGCGCCGCATCCGGAGCCCTCGGGCGACGAGACGCTGCTCGACCGGGTGCTCCGC
CTGCGCAGCGCGGTGCGGAGCCCTCAGGCGTCCGACACCTGGCTCGAAGAACTGGAGACCCAGCTCGTCGAGGAAGCGGT
GCAACGCTGCAACGGCAACATGGCCGCCGCGGCACGGCTGATCGGCATGGCGCGGACGCAGGTGGTCTATCGCATGCGCA
GGAAGAACGTGACGACTCAGGCGAGGGCCTGA

Upstream 100 bases:

>100_bases
GGGGCGATGGCTGCTGCATCGCAACAGCTGCTCCATAGTGGAAAGCGCTGCCCGGCCTCGCGTCGCGAGCGAACAAAATT
CCTCACTCACCGAGGACTCG

Downstream 100 bases:

>100_bases
TCCACCATCTCCACCCAATGCTGCACCGGCACGGCCGTCCCGGACTGCAGGTGCAGGATGCACCCGACGTTGGCCGAGAC
GATCACGTCCGGCTCGTGCG

Product: putative phenol-degradative gene regulator transcription regulator protein

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MSNPLHSHAHGITSMNASPAPNAADFLHAHYLASRSDPSATELRPTHRELAEWLTFDPDTGRIWLDDERMVMLNHQTLGS
LRSELIQGVGVERARGILTRSGYIAGMRDARFVASHWPKEDPVGKLLAGTRLFGLQGLARVEAVHFDYDPERIAFSGEFF
WHHSLEDDEHINAFGVGTDAGCWLPIGYANGYVSTLLGTSIIFRELECRSTGASVCRVIGKAARDWDNVEEDLRYMQAEG
FVGERPGPEPTPRDGPRLGVHDAAADAAPRMVGVSSSFNAACHSLRKVATTTATVLFFGESGVGKELFAKMLHEISERRD
GPFVSVNCAAIPENLVEAELFGVERGAYTGAHASRPGRFERSHRGTLFLDEISSLSLVAQSKLLRALQESEVERVGGTRP
IRLDLRVVAACNVDLREEVRQGRFREDLFFRLNVYPIHLPPLRARSEDVPLLMTHFLKLYGARYGRQIHGFTQRAMRAML
TYTFPGNVRELQNMIERAVIAASDEPQIDTVHLFRDELFNAKSTFAVGDQGRLADTEGSAPSAPHPEPSGDETLLDRVLR
LRSAVRSPQASDTWLEELETQLVEEAVQRCNGNMAAAARLIGMARTQVVYRMRRKNVTTQARA

Sequences:

>Translated_623_residues
MSNPLHSHAHGITSMNASPAPNAADFLHAHYLASRSDPSATELRPTHRELAEWLTFDPDTGRIWLDDERMVMLNHQTLGS
LRSELIQGVGVERARGILTRSGYIAGMRDARFVASHWPKEDPVGKLLAGTRLFGLQGLARVEAVHFDYDPERIAFSGEFF
WHHSLEDDEHINAFGVGTDAGCWLPIGYANGYVSTLLGTSIIFRELECRSTGASVCRVIGKAARDWDNVEEDLRYMQAEG
FVGERPGPEPTPRDGPRLGVHDAAADAAPRMVGVSSSFNAACHSLRKVATTTATVLFFGESGVGKELFAKMLHEISERRD
GPFVSVNCAAIPENLVEAELFGVERGAYTGAHASRPGRFERSHRGTLFLDEISSLSLVAQSKLLRALQESEVERVGGTRP
IRLDLRVVAACNVDLREEVRQGRFREDLFFRLNVYPIHLPPLRARSEDVPLLMTHFLKLYGARYGRQIHGFTQRAMRAML
TYTFPGNVRELQNMIERAVIAASDEPQIDTVHLFRDELFNAKSTFAVGDQGRLADTEGSAPSAPHPEPSGDETLLDRVLR
LRSAVRSPQASDTWLEELETQLVEEAVQRCNGNMAAAARLIGMARTQVVYRMRRKNVTTQARA
>Mature_622_residues
SNPLHSHAHGITSMNASPAPNAADFLHAHYLASRSDPSATELRPTHRELAEWLTFDPDTGRIWLDDERMVMLNHQTLGSL
RSELIQGVGVERARGILTRSGYIAGMRDARFVASHWPKEDPVGKLLAGTRLFGLQGLARVEAVHFDYDPERIAFSGEFFW
HHSLEDDEHINAFGVGTDAGCWLPIGYANGYVSTLLGTSIIFRELECRSTGASVCRVIGKAARDWDNVEEDLRYMQAEGF
VGERPGPEPTPRDGPRLGVHDAAADAAPRMVGVSSSFNAACHSLRKVATTTATVLFFGESGVGKELFAKMLHEISERRDG
PFVSVNCAAIPENLVEAELFGVERGAYTGAHASRPGRFERSHRGTLFLDEISSLSLVAQSKLLRALQESEVERVGGTRPI
RLDLRVVAACNVDLREEVRQGRFREDLFFRLNVYPIHLPPLRARSEDVPLLMTHFLKLYGARYGRQIHGFTQRAMRAMLT
YTFPGNVRELQNMIERAVIAASDEPQIDTVHLFRDELFNAKSTFAVGDQGRLADTEGSAPSAPHPEPSGDETLLDRVLRL
RSAVRSPQASDTWLEELETQLVEEAVQRCNGNMAAAARLIGMARTQVVYRMRRKNVTTQARA

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=339, Percent_Identity=40.4129793510324, Blast_Score=245, Evalue=7e-66,
Organism=Escherichia coli, GI87082117, Length=454, Percent_Identity=34.1409691629956, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790437, Length=345, Percent_Identity=39.1304347826087, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789087, Length=355, Percent_Identity=38.5915492957746, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789233, Length=333, Percent_Identity=38.1381381381381, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=49.3562231759657, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790299, Length=348, Percent_Identity=37.3563218390805, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI87081872, Length=254, Percent_Identity=43.7007874015748, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788905, Length=263, Percent_Identity=40.3041825095057, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=356, Percent_Identity=37.3595505617978, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1787583, Length=239, Percent_Identity=37.6569037656904, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789828, Length=246, Percent_Identity=34.9593495934959, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081858, Length=265, Percent_Identity=30.9433962264151, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 69160; Mature: 69029

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLHSHAHGITSMNASPAPNAADFLHAHYLASRSDPSATELRPTHRELAEWLTFDPDT
CCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCC
GRIWLDDERMVMLNHQTLGSLRSELIQGVGVERARGILTRSGYIAGMRDARFVASHWPKE
CEEEECCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
DPVGKLLAGTRLFGLQGLARVEAVHFDYDPERIAFSGEFFWHHSLEDDEHINAFGVGTDA
CCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCEEEECCCCCCCCCEEEECCCCC
GCWLPIGYANGYVSTLLGTSIIFRELECRSTGASVCRVIGKAARDWDNVEEDLRYMQAEG
CCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
FVGERPGPEPTPRDGPRLGVHDAAADAAPRMVGVSSSFNAACHSLRKVATTTATVLFFGE
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHEEEEEEECC
SGVGKELFAKMLHEISERRDGPFVSVNCAAIPENLVEAELFGVERGAYTGAHASRPGRFE
CCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RSHRGTLFLDEISSLSLVAQSKLLRALQESEVERVGGTRPIRLDLRVVAACNVDLREEVR
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHH
QGRFREDLFFRLNVYPIHLPPLRARSEDVPLLMTHFLKLYGARYGRQIHGFTQRAMRAML
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TYTFPGNVRELQNMIERAVIAASDEPQIDTVHLFRDELFNAKSTFAVGDQGRLADTEGSA
EECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
PSAPHPEPSGDETLLDRVLRLRSAVRSPQASDTWLEELETQLVEEAVQRCNGNMAAAARL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGMARTQVVYRMRRKNVTTQARA
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SNPLHSHAHGITSMNASPAPNAADFLHAHYLASRSDPSATELRPTHRELAEWLTFDPDT
CCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCC
GRIWLDDERMVMLNHQTLGSLRSELIQGVGVERARGILTRSGYIAGMRDARFVASHWPKE
CEEEECCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCHHHHHHHCCCCC
DPVGKLLAGTRLFGLQGLARVEAVHFDYDPERIAFSGEFFWHHSLEDDEHINAFGVGTDA
CCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCCEEEECCCCCCCCCEEEECCCCC
GCWLPIGYANGYVSTLLGTSIIFRELECRSTGASVCRVIGKAARDWDNVEEDLRYMQAEG
CCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
FVGERPGPEPTPRDGPRLGVHDAAADAAPRMVGVSSSFNAACHSLRKVATTTATVLFFGE
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHEEEEEEECC
SGVGKELFAKMLHEISERRDGPFVSVNCAAIPENLVEAELFGVERGAYTGAHASRPGRFE
CCCCHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RSHRGTLFLDEISSLSLVAQSKLLRALQESEVERVGGTRPIRLDLRVVAACNVDLREEVR
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHH
QGRFREDLFFRLNVYPIHLPPLRARSEDVPLLMTHFLKLYGARYGRQIHGFTQRAMRAML
CCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TYTFPGNVRELQNMIERAVIAASDEPQIDTVHLFRDELFNAKSTFAVGDQGRLADTEGSA
EECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
PSAPHPEPSGDETLLDRVLRLRSAVRSPQASDTWLEELETQLVEEAVQRCNGNMAAAARL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGMARTQVVYRMRRKNVTTQARA
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]