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The map label for this gene is 124266138

Identifier: 124266138

GI number: 124266138

Start: 1000573

End: 1002141

Strand: Reverse

Name: 124266138

Synonym: Mpe_A0945

Alternate gene names: NA

Gene position: 1002141-1000573 (Counterclockwise)

Preceding gene: 124266139

Following gene: 124266137

Centisome position: 24.78

GC content: 67.05

Gene sequence:

>1569_bases
ATGAAGACATTCGATTTCAACGACGACGCGGTGGTCGTCATCATCGGCTCCGGCGCCGGCGGCGGCACGCTCGCCAACGA
GCTCTGCCAGAAGGGCATCAAGGTCGTCGTGCTCGAAGCCGGCGCCGTGCAGTCCAACGCCAGCTTCATCAACGACGAGT
GGAAGTCCTTCGGCCAGCTCGCCTGGCTGGACAAGCGCACCACCTCGGGCAGCTGGCGCGTTGCCAAGGACTTCCCCAAC
CTGCCGGCCTGGATCTGCAAGACGGTGGGCGGCACCACCACCCACTGGGCCGGCGCCTCGCTGCGCTTCCAGGAGCACGA
GTTCAAGACCCGCACCACCTACGGCAACGTGGCCGGCGCGAACTTGCAGGACTGGCCGCTGACGCTGGCCGAGCTCGCAC
CCTACTACACGCGCGCCGAGGACAAGATGGGCGTGACGCGGACCCACGGCATCCCCGGCCTGCCCGGCAACAACAACTTC
AAGGTGATGTACAGCGGGGCCACCAAGCTCGGCTACAAGGAAGTGCACACCGGCAACATGGCGATCAACAGCCAGCCGCG
CGACGACCGCGCACGTTGCCTGCAGCTGGGCTTCTGCTTCCAGGGCTGCAAGAGCGGCGCGAAGTGGAGCACGCTCTACA
CCGAGCTGCCCAAGGCCGAGGCCACCGGCAACTTCGAGCTGCGCCCCGAGAGCCACGTGACGCGCATCGAGCACGACGCC
AAGGGCAAGGTGACCGGCGTCGTCTACTTCGACAAGGACGGCAAGGAACAGCGCCAGAAGGCCCGCATCGTGGCGGTGGC
CGGCAACTCGATCGAGACGCCGCGCCTGCTGCTGCTGTCGGCCTCGAAGATGTTCAAGGACGGCCTGGCGAACAGCTCGG
GCCAGGTGGGCCGCAACTACATGCGCCACGTGACCGGCTCGGTGTACGGGCTGTTCGAGAACCCCGTCCACATGTACCGC
GGCACCACGATGGCCGGCATCGTGCGCGACGAAGCGCACAACAACACGAAGCGCGGCTTCGTCGGCGGCTACGAGTTGGA
GACGCTGTCGCTGGGCCTGCCCTTCATGGCCGCGTTCCTGAACCCGGGCGGCTGGGGTGCCGACTTCTCCGAGTACCTGG
AGAACTACACGCAGCTGGCCGGCATGTGGATCGTCGGCGAGGACATGCCGCGCGAGACCAACCGCGTCACGCTGCACAGG
ACGCTGAAGGACAAGTGGGGCAGCGCGATCCCCAACGTGCACTTCGACGACCACGAGAACGACCTGAAGCTGCGCGAGCA
CGCCTTCACCCAGGGCCAGCGCGTCTACGAGGCGGCCGGTGCCCGCAAGTCCTTCCGCACGCCGCCCTACCCGTCGACGC
ACAACCTCGGCACCTGCCGCATGGGCGCCTCGGCCAAGAGCAGCGTCTGCAACTCGTACGGGCAGACGCACGACATCGCG
AACCTGTTCATCTCGGACGGCAGCCAGTTCACCACCGGCGGCGCGGAGAACCCGACGCTGACGATCGTGACGCTCGCGAT
CCGGCAGGCCGAGTACATCGCCCAGCAGATGAGCGCCCGGGCGATCTGA

Upstream 100 bases:

>100_bases
CTGGCTGCCGGCGCCGCCCACCGAGGCGAGCCCGCCGCCCTACATGGGCTGAGCCCCTTCGTCGCCCCGACAACCCAGCT
AACGCGAGGCTAGTACCCCC

Downstream 100 bases:

>100_bases
GCCCAGGTCGCGCGGGGCGGCACGCCGGGAGGAGCCGGCGTGCCGCCCTCCCGAGCGGTCCGGGCCCGACCCCCGGACCT
CCCAAGAACGGTGCCTGACG

Product: putative 2-keto-gluconate dehydrogenase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKTFDFNDDAVVVIIGSGAGGGTLANELCQKGIKVVVLEAGAVQSNASFINDEWKSFGQLAWLDKRTTSGSWRVAKDFPN
LPAWICKTVGGTTTHWAGASLRFQEHEFKTRTTYGNVAGANLQDWPLTLAELAPYYTRAEDKMGVTRTHGIPGLPGNNNF
KVMYSGATKLGYKEVHTGNMAINSQPRDDRARCLQLGFCFQGCKSGAKWSTLYTELPKAEATGNFELRPESHVTRIEHDA
KGKVTGVVYFDKDGKEQRQKARIVAVAGNSIETPRLLLLSASKMFKDGLANSSGQVGRNYMRHVTGSVYGLFENPVHMYR
GTTMAGIVRDEAHNNTKRGFVGGYELETLSLGLPFMAAFLNPGGWGADFSEYLENYTQLAGMWIVGEDMPRETNRVTLHR
TLKDKWGSAIPNVHFDDHENDLKLREHAFTQGQRVYEAAGARKSFRTPPYPSTHNLGTCRMGASAKSSVCNSYGQTHDIA
NLFISDGSQFTTGGAENPTLTIVTLAIRQAEYIAQQMSARAI

Sequences:

>Translated_522_residues
MKTFDFNDDAVVVIIGSGAGGGTLANELCQKGIKVVVLEAGAVQSNASFINDEWKSFGQLAWLDKRTTSGSWRVAKDFPN
LPAWICKTVGGTTTHWAGASLRFQEHEFKTRTTYGNVAGANLQDWPLTLAELAPYYTRAEDKMGVTRTHGIPGLPGNNNF
KVMYSGATKLGYKEVHTGNMAINSQPRDDRARCLQLGFCFQGCKSGAKWSTLYTELPKAEATGNFELRPESHVTRIEHDA
KGKVTGVVYFDKDGKEQRQKARIVAVAGNSIETPRLLLLSASKMFKDGLANSSGQVGRNYMRHVTGSVYGLFENPVHMYR
GTTMAGIVRDEAHNNTKRGFVGGYELETLSLGLPFMAAFLNPGGWGADFSEYLENYTQLAGMWIVGEDMPRETNRVTLHR
TLKDKWGSAIPNVHFDDHENDLKLREHAFTQGQRVYEAAGARKSFRTPPYPSTHNLGTCRMGASAKSSVCNSYGQTHDIA
NLFISDGSQFTTGGAENPTLTIVTLAIRQAEYIAQQMSARAI
>Mature_522_residues
MKTFDFNDDAVVVIIGSGAGGGTLANELCQKGIKVVVLEAGAVQSNASFINDEWKSFGQLAWLDKRTTSGSWRVAKDFPN
LPAWICKTVGGTTTHWAGASLRFQEHEFKTRTTYGNVAGANLQDWPLTLAELAPYYTRAEDKMGVTRTHGIPGLPGNNNF
KVMYSGATKLGYKEVHTGNMAINSQPRDDRARCLQLGFCFQGCKSGAKWSTLYTELPKAEATGNFELRPESHVTRIEHDA
KGKVTGVVYFDKDGKEQRQKARIVAVAGNSIETPRLLLLSASKMFKDGLANSSGQVGRNYMRHVTGSVYGLFENPVHMYR
GTTMAGIVRDEAHNNTKRGFVGGYELETLSLGLPFMAAFLNPGGWGADFSEYLENYTQLAGMWIVGEDMPRETNRVTLHR
TLKDKWGSAIPNVHFDDHENDLKLREHAFTQGQRVYEAAGARKSFRTPPYPSTHNLGTCRMGASAKSSVCNSYGQTHDIA
NLFISDGSQFTTGGAENPTLTIVTLAIRQAEYIAQQMSARAI

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 57367; Mature: 57367

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFDFNDDAVVVIIGSGAGGGTLANELCQKGIKVVVLEAGAVQSNASFINDEWKSFGQL
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCE
AWLDKRTTSGSWRVAKDFPNLPAWICKTVGGTTTHWAGASLRFQEHEFKTRTTYGNVAGA
EEEECCCCCCCEEECCCCCCCHHHHHHHCCCCCEECCCCEEEEEHHHCEEECCCCCCCCC
NLQDWPLTLAELAPYYTRAEDKMGVTRTHGIPGLPGNNNFKVMYSGATKLGYKEVHTGNM
CCCCCCCCHHHHCCHHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCEEEECCCE
AINSQPRDDRARCLQLGFCFQGCKSGAKWSTLYTELPKAEATGNFELRPESHVTRIEHDA
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEECCHHHHHHHCCCC
KGKVTGVVYFDKDGKEQRQKARIVAVAGNSIETPRLLLLSASKMFKDGLANSSGQVGRNY
CCCEEEEEEECCCCHHHHHHEEEEEEECCCCCCCEEEEEEHHHHHHHHCCCCCCHHHHHH
MRHVTGSVYGLFENPVHMYRGTTMAGIVRDEAHNNTKRGFVGGYELETLSLGLPFMAAFL
HHHHHCCEEEEECCCCHHHCCCCCEEEEEHHCCCCCCCCCCCCEEEEEEECCHHHHHHHC
NPGGWGADFSEYLENYTQLAGMWIVGEDMPRETNRVTLHRTLKDKWGSAIPNVHFDDHEN
CCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCC
DLKLREHAFTQGQRVYEAAGARKSFRTPPYPSTHNLGTCRMGASAKSSVCNSYGQTHDIA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCHHHH
NLFISDGSQFTTGGAENPTLTIVTLAIRQAEYIAQQMSARAI
EEEEECCCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTFDFNDDAVVVIIGSGAGGGTLANELCQKGIKVVVLEAGAVQSNASFINDEWKSFGQL
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCE
AWLDKRTTSGSWRVAKDFPNLPAWICKTVGGTTTHWAGASLRFQEHEFKTRTTYGNVAGA
EEEECCCCCCCEEECCCCCCCHHHHHHHCCCCCEECCCCEEEEEHHHCEEECCCCCCCCC
NLQDWPLTLAELAPYYTRAEDKMGVTRTHGIPGLPGNNNFKVMYSGATKLGYKEVHTGNM
CCCCCCCCHHHHCCHHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCEEEECCCE
AINSQPRDDRARCLQLGFCFQGCKSGAKWSTLYTELPKAEATGNFELRPESHVTRIEHDA
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEECCHHHHHHHCCCC
KGKVTGVVYFDKDGKEQRQKARIVAVAGNSIETPRLLLLSASKMFKDGLANSSGQVGRNY
CCCEEEEEEECCCCHHHHHHEEEEEEECCCCCCCEEEEEEHHHHHHHHCCCCCCHHHHHH
MRHVTGSVYGLFENPVHMYRGTTMAGIVRDEAHNNTKRGFVGGYELETLSLGLPFMAAFL
HHHHHCCEEEEECCCCHHHCCCCCEEEEEHHCCCCCCCCCCCCEEEEEEECCHHHHHHHC
NPGGWGADFSEYLENYTQLAGMWIVGEDMPRETNRVTLHRTLKDKWGSAIPNVHFDDHEN
CCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCCCC
DLKLREHAFTQGQRVYEAAGARKSFRTPPYPSTHNLGTCRMGASAKSSVCNSYGQTHDIA
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCHHHH
NLFISDGSQFTTGGAENPTLTIVTLAIRQAEYIAQQMSARAI
EEEEECCCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]