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The map label for this gene is fabG [H]

Identifier: 124265870

GI number: 124265870

Start: 713092

End: 713781

Strand: Reverse

Name: fabG [H]

Synonym: Mpe_A0677

Alternate gene names: 124265870

Gene position: 713781-713092 (Counterclockwise)

Preceding gene: 124265871

Following gene: 124265869

Centisome position: 17.65

GC content: 73.77

Gene sequence:

>690_bases
ATGACAGGAAACCCTCTGAGCCTGAGCGGACGGCGTGCGCTGATCACCCAGGCCGATGCCTTCATGGGGCCGGCGCTGTG
CGAGGTGTTCGCCGCGCACGGCGCAGACGTGATCGCCGACACCTCACCGCTGGCCGACGCCGATGCGCCGGCGCGGGTGG
TGGCCGCGGCCGGCGTGGTGGACCTGCTGGTGCTCAACCTGGCGATCCCGGCGCCGCGCACCAGCGCGGTGGCGTCGTCC
GATGCCGAGTGGGCGGCGGTGTTCGGCGCGCTGGTCGACCCGCTGCCGCGGCTGCTGCGCGCGGTGCTGCCGCAGATGAT
CGCGCGGCGCGCGGGCCGGGTGGTGCTGATGGGCAGCGCCGCGGCGCTGCGCGGCATGAAGAACAGCTCGACCTACAGCG
CCGCGCGCGGCGCGCAGCTGGCCTATGTGCAGGCGGTCGGCGTCGAGGTGGCGCCGCACGGCGTGCGGGTGAACGCGATC
GCGCAGAACTTCGTCGACAACCCGACCTACTTCCCGCCCGAGGTGCAGGCCGACCCGCGCTTCCAGGAGCGCCTGAAGCG
CGAGGTGCCGCTGGGCCGCCTGGTCGGCGCGCGCGAGGATGCCGAGTTCGCCGCCTACCTGTGCAGCGAGCCGGCCGACT
GCTTCGTGGGCCAGGTGTTCCCGGTGTGTGGAGGCTGGGTGCCGCGATGA

Upstream 100 bases:

>100_bases
AGCCCGCTCGAGCACCAGTGCCAGGCGCTGTGGGCCGAGACGCAGCGCGTGATGCACCAACCGCGCCGCTGACCGACACC
GTGACCGAAAGGACCGACGC

Downstream 100 bases:

>100_bases
GGCTGACCGACCTGGGCCCGCTGCCGCTGACGCTGATCGCGTCGCTGCTGCTCGCCGTGGTGCTGCTGGCGGTGCGTGTG
TTCGTGATGCAGCGCGTGCA

Product: putative oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTGNPLSLSGRRALITQADAFMGPALCEVFAAHGADVIADTSPLADADAPARVVAAAGVVDLLVLNLAIPAPRTSAVASS
DAEWAAVFGALVDPLPRLLRAVLPQMIARRAGRVVLMGSAAALRGMKNSSTYSAARGAQLAYVQAVGVEVAPHGVRVNAI
AQNFVDNPTYFPPEVQADPRFQERLKREVPLGRLVGAREDAEFAAYLCSEPADCFVGQVFPVCGGWVPR

Sequences:

>Translated_229_residues
MTGNPLSLSGRRALITQADAFMGPALCEVFAAHGADVIADTSPLADADAPARVVAAAGVVDLLVLNLAIPAPRTSAVASS
DAEWAAVFGALVDPLPRLLRAVLPQMIARRAGRVVLMGSAAALRGMKNSSTYSAARGAQLAYVQAVGVEVAPHGVRVNAI
AQNFVDNPTYFPPEVQADPRFQERLKREVPLGRLVGAREDAEFAAYLCSEPADCFVGQVFPVCGGWVPR
>Mature_228_residues
TGNPLSLSGRRALITQADAFMGPALCEVFAAHGADVIADTSPLADADAPARVVAAAGVVDLLVLNLAIPAPRTSAVASSD
AEWAAVFGALVDPLPRLLRAVLPQMIARRAGRVVLMGSAAALRGMKNSSTYSAARGAQLAYVQAVGVEVAPHGVRVNAIA
QNFVDNPTYFPPEVQADPRFQERLKREVPLGRLVGAREDAEFAAYLCSEPADCFVGQVFPVCGGWVPR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=201, Percent_Identity=27.363184079602, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=24.3027888446215, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=25.4437869822485, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=28.1632653061224, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=29.0836653386454, Blast_Score=82, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=27.8225806451613, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 23989; Mature: 23858

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNPLSLSGRRALITQADAFMGPALCEVFAAHGADVIADTSPLADADAPARVVAAAGVV
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHH
DLLVLNLAIPAPRTSAVASSDAEWAAVFGALVDPLPRLLRAVLPQMIARRAGRVVLMGSA
HHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECH
AALRGMKNSSTYSAARGAQLAYVQAVGVEVAPHGVRVNAIAQNFVDNPTYFPPEVQADPR
HHHHCCCCCCCHHHHCCCCEEEEEEECCEECCCCEEHHHHHHHHCCCCCCCCCCCCCCCH
FQERLKREVPLGRLVGAREDAEFAAYLCSEPADCFVGQVFPVCGGWVPR
HHHHHHHHCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TGNPLSLSGRRALITQADAFMGPALCEVFAAHGADVIADTSPLADADAPARVVAAAGVV
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHH
DLLVLNLAIPAPRTSAVASSDAEWAAVFGALVDPLPRLLRAVLPQMIARRAGRVVLMGSA
HHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECH
AALRGMKNSSTYSAARGAQLAYVQAVGVEVAPHGVRVNAIAQNFVDNPTYFPPEVQADPR
HHHHCCCCCCCHHHHCCCCEEEEEEECCEECCCCEEHHHHHHHHCCCCCCCCCCCCCCCH
FQERLKREVPLGRLVGAREDAEFAAYLCSEPADCFVGQVFPVCGGWVPR
HHHHHHHHCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]