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The map label for this gene is era [H]

Identifier: 124265844

GI number: 124265844

Start: 684510

End: 685448

Strand: Direct

Name: era [H]

Synonym: Mpe_A0651

Alternate gene names: 124265844

Gene position: 684510-685448 (Clockwise)

Preceding gene: 124265843

Following gene: 124265845

Centisome position: 16.93

GC content: 68.16

Gene sequence:

>939_bases
ATGAACGACAGCACCACCGCCGCCCCTGCTGCGGGCGCAGAGATGCCCGAGCAGCGCTGCGGCCTCGTGGCGATCGTCGG
CCGGCCCAATGTCGGCAAGTCGACCCTGCTCAACGCCCTGGTCGGGCAGAAGGTCAGCATCACCTCACGCAAGGCGCAGA
CCACGCGCCACCGCATCACCGGCATCCGCAGCGCCGACGCGGCGCAGTTCGTGTTCGTCGACACCCCCGGCTTCCAGACC
CGCCACACCGTCAAGGGCGCCGGTGCGCTGAACCGCAACCTGAACAAGACCGTCCAGTCGGTGATGGGCGACGTGGACGT
GGTGCTGTTCGTCGTCGAGGCCGGCCGCTTCGGGCTCGACGATGCCAAGGTGCTATCGCTCGTGCCGCCGGGCAAGCCGA
CGCTGCTGGTCGCGAACAAGCTCGACCTGGTGCGCCGTCGCGCCGAACTCGCGCCCTGGCTCAAGAGCATGCAGGAGCGC
CATCCGTTCGCCGAGTTCGTGCCGCTGGCGGCCACCAGCCCCGACGACGTGCGGCGCCTGCTCCAGATCGTCCAACCCTA
CCTGCCCGAGCAGCCGTGGTTCTACGACGAGGAGGCCCTGACCGATCGCAGCGAGCGCTTCCTCGCCAGCGAGATCATCC
GCGAGAAGCTGTTCCGGCTGACCGGGGACGAGCTTCCCTACACGTCGACCGTGGTGATCGACGAGTTCAAGGAAGAGGGC
GCGCTGCGCCGTATCGCCGCCACCATCATCGTCGAGCGCGAGGCCCACAAGGGCATGGTCATCGGCGACAAGGGGGAGCG
CCTGAAGCGCATCGGCACTGATGCGCGCGTCGAGCTCGAGCGCCTGATGGACGGCAAGGTCTTCCTCGAGATCTGGGTCA
AGGTGCGTTCCGGCTGGGCCGACGACGAGGCCCGCCTCAAGAGCTACGGCTACGAGTGA

Upstream 100 bases:

>100_bases
CGCTCGAAGTTCGCGGTGAAGGGCGGTCCCGGCGTGCCGCCGAGCAGGAGGCCGCCCGTGCGGCGCTGGCTACACTGAAG
CCAGACGAAACCGAGCGCCC

Downstream 100 bases:

>100_bases
GAGCCGCCGCGTCGCGCGTCGCCGGCGCCACCCCGCAGGCTGCCCGTGGCGGCCGTGCTGCGGCCCCGGCGCTGCAGCCG
GCCTACCTGCTGCACCGCTA

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNDSTTAAPAAGAEMPEQRCGLVAIVGRPNVGKSTLLNALVGQKVSITSRKAQTTRHRITGIRSADAAQFVFVDTPGFQT
RHTVKGAGALNRNLNKTVQSVMGDVDVVLFVVEAGRFGLDDAKVLSLVPPGKPTLLVANKLDLVRRRAELAPWLKSMQER
HPFAEFVPLAATSPDDVRRLLQIVQPYLPEQPWFYDEEALTDRSERFLASEIIREKLFRLTGDELPYTSTVVIDEFKEEG
ALRRIAATIIVEREAHKGMVIGDKGERLKRIGTDARVELERLMDGKVFLEIWVKVRSGWADDEARLKSYGYE

Sequences:

>Translated_312_residues
MNDSTTAAPAAGAEMPEQRCGLVAIVGRPNVGKSTLLNALVGQKVSITSRKAQTTRHRITGIRSADAAQFVFVDTPGFQT
RHTVKGAGALNRNLNKTVQSVMGDVDVVLFVVEAGRFGLDDAKVLSLVPPGKPTLLVANKLDLVRRRAELAPWLKSMQER
HPFAEFVPLAATSPDDVRRLLQIVQPYLPEQPWFYDEEALTDRSERFLASEIIREKLFRLTGDELPYTSTVVIDEFKEEG
ALRRIAATIIVEREAHKGMVIGDKGERLKRIGTDARVELERLMDGKVFLEIWVKVRSGWADDEARLKSYGYE
>Mature_312_residues
MNDSTTAAPAAGAEMPEQRCGLVAIVGRPNVGKSTLLNALVGQKVSITSRKAQTTRHRITGIRSADAAQFVFVDTPGFQT
RHTVKGAGALNRNLNKTVQSVMGDVDVVLFVVEAGRFGLDDAKVLSLVPPGKPTLLVANKLDLVRRRAELAPWLKSMQER
HPFAEFVPLAATSPDDVRRLLQIVQPYLPEQPWFYDEEALTDRSERFLASEIIREKLFRLTGDELPYTSTVVIDEFKEEG
ALRRIAATIIVEREAHKGMVIGDKGERLKRIGTDARVELERLMDGKVFLEIWVKVRSGWADDEARLKSYGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=50.5084745762712, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI87082120, Length=178, Percent_Identity=32.5842696629214, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532761, Length=160, Percent_Identity=31.875, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646434, Length=326, Percent_Identity=26.0736196319018, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34752; Mature: 34752

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSTTAAPAAGAEMPEQRCGLVAIVGRPNVGKSTLLNALVGQKVSITSRKAQTTRHRIT
CCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHH
GIRSADAAQFVFVDTPGFQTRHTVKGAGALNRNLNKTVQSVMGDVDVVLFVVEAGRFGLD
CCCCCCCEEEEEEECCCCCCCCEECCCCHHCCHHHHHHHHHHCCHHHEEEEEECCCCCCC
DAKVLSLVPPGKPTLLVANKLDLVRRRAELAPWLKSMQERHPFAEFVPLAATSPDDVRRL
CCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHH
LQIVQPYLPEQPWFYDEEALTDRSERFLASEIIREKLFRLTGDELPYTSTVVIDEFKEEG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
ALRRIAATIIVEREAHKGMVIGDKGERLKRIGTDARVELERLMDGKVFLEIWVKVRSGWA
HHHHHHHHHHEEECCCCCCEECCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCC
DDEARLKSYGYE
CCHHHHHHCCCC
>Mature Secondary Structure
MNDSTTAAPAAGAEMPEQRCGLVAIVGRPNVGKSTLLNALVGQKVSITSRKAQTTRHRIT
CCCCCCCCCCCCCCCCHHHCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHH
GIRSADAAQFVFVDTPGFQTRHTVKGAGALNRNLNKTVQSVMGDVDVVLFVVEAGRFGLD
CCCCCCCEEEEEEECCCCCCCCEECCCCHHCCHHHHHHHHHHCCHHHEEEEEECCCCCCC
DAKVLSLVPPGKPTLLVANKLDLVRRRAELAPWLKSMQERHPFAEFVPLAATSPDDVRRL
CCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHH
LQIVQPYLPEQPWFYDEEALTDRSERFLASEIIREKLFRLTGDELPYTSTVVIDEFKEEG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
ALRRIAATIIVEREAHKGMVIGDKGERLKRIGTDARVELERLMDGKVFLEIWVKVRSGWA
HHHHHHHHHHEEECCCCCCEECCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCC
DDEARLKSYGYE
CCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]