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The map label for this gene is argS

Identifier: 124265346

GI number: 124265346

Start: 160116

End: 161801

Strand: Reverse

Name: argS

Synonym: Mpe_A0153

Alternate gene names: 124265346

Gene position: 161801-160116 (Counterclockwise)

Preceding gene: 124265349

Following gene: 124265345

Centisome position: 4.0

GC content: 69.57

Gene sequence:

>1686_bases
ATGATCCGTGCCCAGCAAGAGCTCCTGGTGGCCCTCGGCGATGCCCTCGCCGAACTGGCGCCCGAGCAGCCCCCGATTGC
CGCCTTCGAGAGTCCGAAACAGGCCGCCCACGGCGACCTCGCCATCACCTCGGCGATGCAGCTCGCCAAGCCGCTCAAGC
GCAATCCGCGCGAGCTGGCCCAGGCCCTGATCGACGCACTGCAGCGCCGTGAAGCGGTGCAGCGCTGGGTCGCGGCGCTC
GAGATCGCCGGCCCCGGCTTCATCAACCTGCGGCTCAAGGACACCACCAAGCAGCAGATCGTCGCCGAGGTGCTGGCGAG
CGGCACCGATTTCGGCCGCCAGCCGGCCACGAGCGAGCGGGCGCTGGTCGAGTTCGTCTCCGCCAACCCTACCGGCCCGC
TGCACGTGGGCCATGGCCGCCAGGCGGCGCTCGGCGATGCGATCTGCAAACTGTTCGAGACGCAGGGCTGGCAGGTCACG
CGCGAGTTCTATTACAACGACGCCGGCGTGCAGATCGGCACGCTCGCCGCGTCGACCCAGGCCCGCCTCCAGGGCCTGAA
GCCGGGTGACGCGGGCTGGCCGGAGAGCGCCTACAACGGCGACTACATCGCCGACATCGCCGCCGACTTCCTGGCCCGCA
AGACCGTCAAGGCCGACGACCGCGAGTTCACCGCTTCCGGCGACCCCGCCGACCTGGACGGCATCCGCCAGTTCGCCGTG
GCCTACCTGCGCCACGAGCAGGATCTCGACCTGCAGGCCTTCGGCGTCCGGTTCGACCACTACTTCCTCGAATCCAGCCT
CTACGCCACCGGCCGCGTCGAGGCCACGGTGGGCAAGCTGGTCGCGGCCGGCAAGACCTTCGAGGACGGCGGCGCACTGT
GGCTGCGCACCACGGACTATGGCGACGACAAGGATCGCGTCATGAAGAAGTCCGACGGCAGCTACACCTACTTCGTGCCC
GACGTGGCCTACCACGTCAACAAGTGGGAACGCGGCTACCACAAGGTCATCAACATCCAGGGCAGCGACCACCACGGCAC
CATCGCGCGGGTGCGCGCCGGGCTGCAGGCCGCCGACGTGGGCATTCCCGCGGGCTACCCCGACTACGTGCTGCACAAGA
TGGTCACCGTGATGCGCGGCGGCGAGGAGGTCAAGATCTCCAAGCGCGCCGGCAGCTACGTGACGCTGCGGGACCTGATC
GACTGGACCGGCAAGGACGCGGTGCGCTTCTTCCTGATCAGCCGCAAGGCCGACACCGAGTTCGTGTTCGACGTCGACCT
GGCGCTGAAGAAGAACGACGAGAACCCGGTCTACTACGTGCAGTACGCGCATGCGCGCATCTGCTCGGTCATCGTGCAGT
GGCGCGAGCAGCAGGCCGGCGACCCGGCCACGCTGGCCCAGGCCGATCTCGCGCGGCTGGTGGCCCCCACCGAGGCCGCA
CTGATGCTCAAGCTGGCCGCCTACCCGGTGATGCTGAGCGGCGCCGCCGAGAGCCTGGCGCCGCACGACGTGGCGTTCTA
CCTGCGCGACCTGGCGGGCGCCTTCCACAGCTATTACGCGGCCGAGCGCTTTCTCACCGACGACCCGGCGCTGAGCCGCG
CGCGGCTGGCGCTGCTCGCCGCCACCGCGCAGGTGCTGCGCAACGGCCTGGCGGTGCTCGGCGTCAGCGCCCCCGACAGG
ATGTGA

Upstream 100 bases:

>100_bases
CCGCCCTGATGTCAGGGACGGGGATGCCACGCTCGCCGGCCCGCCCGCCGTGAAGGACTGCCCATCGATCGCGTGCCGAC
CCCGCCCCTAGAATCCGGCG

Downstream 100 bases:

>100_bases
CCGGAGCTGCCATGCCCTTCTTCCCCTTCTCTCGTCGCTCGTCGCAGCACGGTGGCTTCATCGTCGGCCTGATCGCCGGC
CTGCTGATCGGCCTGGCGCT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MIRAQQELLVALGDALAELAPEQPPIAAFESPKQAAHGDLAITSAMQLAKPLKRNPRELAQALIDALQRREAVQRWVAAL
EIAGPGFINLRLKDTTKQQIVAEVLASGTDFGRQPATSERALVEFVSANPTGPLHVGHGRQAALGDAICKLFETQGWQVT
REFYYNDAGVQIGTLAASTQARLQGLKPGDAGWPESAYNGDYIADIAADFLARKTVKADDREFTASGDPADLDGIRQFAV
AYLRHEQDLDLQAFGVRFDHYFLESSLYATGRVEATVGKLVAAGKTFEDGGALWLRTTDYGDDKDRVMKKSDGSYTYFVP
DVAYHVNKWERGYHKVINIQGSDHHGTIARVRAGLQAADVGIPAGYPDYVLHKMVTVMRGGEEVKISKRAGSYVTLRDLI
DWTGKDAVRFFLISRKADTEFVFDVDLALKKNDENPVYYVQYAHARICSVIVQWREQQAGDPATLAQADLARLVAPTEAA
LMLKLAAYPVMLSGAAESLAPHDVAFYLRDLAGAFHSYYAAERFLTDDPALSRARLALLAATAQVLRNGLAVLGVSAPDR
M

Sequences:

>Translated_561_residues
MIRAQQELLVALGDALAELAPEQPPIAAFESPKQAAHGDLAITSAMQLAKPLKRNPRELAQALIDALQRREAVQRWVAAL
EIAGPGFINLRLKDTTKQQIVAEVLASGTDFGRQPATSERALVEFVSANPTGPLHVGHGRQAALGDAICKLFETQGWQVT
REFYYNDAGVQIGTLAASTQARLQGLKPGDAGWPESAYNGDYIADIAADFLARKTVKADDREFTASGDPADLDGIRQFAV
AYLRHEQDLDLQAFGVRFDHYFLESSLYATGRVEATVGKLVAAGKTFEDGGALWLRTTDYGDDKDRVMKKSDGSYTYFVP
DVAYHVNKWERGYHKVINIQGSDHHGTIARVRAGLQAADVGIPAGYPDYVLHKMVTVMRGGEEVKISKRAGSYVTLRDLI
DWTGKDAVRFFLISRKADTEFVFDVDLALKKNDENPVYYVQYAHARICSVIVQWREQQAGDPATLAQADLARLVAPTEAA
LMLKLAAYPVMLSGAAESLAPHDVAFYLRDLAGAFHSYYAAERFLTDDPALSRARLALLAATAQVLRNGLAVLGVSAPDR
M
>Mature_561_residues
MIRAQQELLVALGDALAELAPEQPPIAAFESPKQAAHGDLAITSAMQLAKPLKRNPRELAQALIDALQRREAVQRWVAAL
EIAGPGFINLRLKDTTKQQIVAEVLASGTDFGRQPATSERALVEFVSANPTGPLHVGHGRQAALGDAICKLFETQGWQVT
REFYYNDAGVQIGTLAASTQARLQGLKPGDAGWPESAYNGDYIADIAADFLARKTVKADDREFTASGDPADLDGIRQFAV
AYLRHEQDLDLQAFGVRFDHYFLESSLYATGRVEATVGKLVAAGKTFEDGGALWLRTTDYGDDKDRVMKKSDGSYTYFVP
DVAYHVNKWERGYHKVINIQGSDHHGTIARVRAGLQAADVGIPAGYPDYVLHKMVTVMRGGEEVKISKRAGSYVTLRDLI
DWTGKDAVRFFLISRKADTEFVFDVDLALKKNDENPVYYVQYAHARICSVIVQWREQQAGDPATLAQADLARLVAPTEAA
LMLKLAAYPVMLSGAAESLAPHDVAFYLRDLAGAFHSYYAAERFLTDDPALSRARLALLAATAQVLRNGLAVLGVSAPDR
M

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=633, Percent_Identity=24.9605055292259, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1788184, Length=570, Percent_Identity=26.140350877193, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71985061, Length=605, Percent_Identity=23.9669421487603, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985068, Length=559, Percent_Identity=23.9713774597496, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18859963, Length=606, Percent_Identity=23.7623762376238, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571570, Length=537, Percent_Identity=23.2774674115456, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_METPP (A2SC26)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019350.1
- ProteinModelPortal:   A2SC26
- STRING:   A2SC26
- GeneID:   4784116
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0153
- NMPDR:   fig|279263.3.peg.300
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   MPET420662:MPE_A0153-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61339; Mature: 61339

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAQQELLVALGDALAELAPEQPPIAAFESPKQAAHGDLAITSAMQLAKPLKRNPRELA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHH
QALIDALQRREAVQRWVAALEIAGPGFINLRLKDTTKQQIVAEVLASGTDFGRQPATSER
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCHH
ALVEFVSANPTGPLHVGHGRQAALGDAICKLFETQGWQVTREFYYNDAGVQIGTLAASTQ
HHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEHEECCCCCEEEEEHHHHH
ARLQGLKPGDAGWPESAYNGDYIADIAADFLARKTVKADDREFTASGDPADLDGIRQFAV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHH
AYLRHEQDLDLQAFGVRFDHYFLESSLYATGRVEATVGKLVAAGKTFEDGGALWLRTTDY
HHHHCCCCCCCEEECEEHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCCCEEEEEECCC
GDDKDRVMKKSDGSYTYFVPDVAYHVNKWERGYHKVINIQGSDHHGTIARVRAGLQAADV
CCCHHHHHHCCCCCEEEECCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCHHHCC
GIPAGYPDYVLHKMVTVMRGGEEVKISKRAGSYVTLRDLIDWTGKDAVRFFLISRKADTE
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHCCCCCCEEEEEEEECCCCCE
FVFDVDLALKKNDENPVYYVQYAHARICSVIVQWREQQAGDPATLAQADLARLVAPTEAA
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
LMLKLAAYPVMLSGAAESLAPHDVAFYLRDLAGAFHSYYAAERFLTDDPALSRARLALLA
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ATAQVLRNGLAVLGVSAPDRM
HHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MIRAQQELLVALGDALAELAPEQPPIAAFESPKQAAHGDLAITSAMQLAKPLKRNPRELA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHH
QALIDALQRREAVQRWVAALEIAGPGFINLRLKDTTKQQIVAEVLASGTDFGRQPATSER
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCHH
ALVEFVSANPTGPLHVGHGRQAALGDAICKLFETQGWQVTREFYYNDAGVQIGTLAASTQ
HHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEHEECCCCCEEEEEHHHHH
ARLQGLKPGDAGWPESAYNGDYIADIAADFLARKTVKADDREFTASGDPADLDGIRQFAV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHH
AYLRHEQDLDLQAFGVRFDHYFLESSLYATGRVEATVGKLVAAGKTFEDGGALWLRTTDY
HHHHCCCCCCCEEECEEHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCCCEEEEEECCC
GDDKDRVMKKSDGSYTYFVPDVAYHVNKWERGYHKVINIQGSDHHGTIARVRAGLQAADV
CCCHHHHHHCCCCCEEEECCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCHHHCC
GIPAGYPDYVLHKMVTVMRGGEEVKISKRAGSYVTLRDLIDWTGKDAVRFFLISRKADTE
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHCCCCCCEEEEEEEECCCCCE
FVFDVDLALKKNDENPVYYVQYAHARICSVIVQWREQQAGDPATLAQADLARLVAPTEAA
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
LMLKLAAYPVMLSGAAESLAPHDVAFYLRDLAGAFHSYYAAERFLTDDPALSRARLALLA
HHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ATAQVLRNGLAVLGVSAPDRM
HHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA