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The map label for this gene is ycbL [H]

Identifier: 124265285

GI number: 124265285

Start: 87547

End: 88194

Strand: Direct

Name: ycbL [H]

Synonym: Mpe_A0092

Alternate gene names: 124265285

Gene position: 87547-88194 (Clockwise)

Preceding gene: 124265284

Following gene: 124265288

Centisome position: 2.16

GC content: 71.6

Gene sequence:

>648_bases
ATGCTCCAGTACCTCACTGTCCCCGTCACCGCCTTCCAGCAGAACTGCTCCATCGTGTGGTGCGACGCCACGCGCCGCGC
CGCCGTCATCGATCCCGGCGGTGAGCTGCCGCGGCTGCGGGCCGAGGTGCGGCGGCTGGGGCTCACGCTCGAGGCGATCT
GGCTGACCCACGCGCACATCGACCATGCGGGCGGCACCGCGCAACTCGCCCGCGAGGACGCGCTGCCGATCATCGGGCCG
CACGCGGCCGACCAGTTCTGGATCGACGGGCTGGCGCAGCAGAGCCGGATGTTCGGCTTTCCCCCCAGCGAGCCGTTCAC
GCCGACGCGCTGGCTCTGCCCCGGCGGCGTGGACGACCGCGTGACCCTGGGCGACTGCGAGCTCGAGGTGCGGCACTGTC
CCGGGCACACGCCGGGGCACGTGGTGTTCGTCTCGCGAGAAGCCCAAAGGGCCTTCGTCGGCGACGTGCTGTTCGCTGGC
GGCATCGGCCGCACCGATTTCCCGCTGGGCGATCACGACACGCTGGTGGCGGCGATCCGCACCCAGCTCTGGCCGCTCGG
TGATGACATCGTGTTCATCCCCGGCCACGGGCCGGAGAGCAGCTTCGGCCGCGAGCGGCGCCACAACCCCTACGTGCGCG
ACGTCTGA

Upstream 100 bases:

>100_bases
TGCCATCGATGGATCGAGGCGCCCTGGCGAGCGAAACTGCGCGGACCTTCCGTCTTTTGAGAGGGCGCTTGCGCACGCCG
CACGGCAACCCGGTCATACG

Downstream 100 bases:

>100_bases
GCGCCCGCGCTCGCGCCCCTGCGCTCAGCGCGACTGCTCGCGCGTCGGCGTGGCGGGCTTGGTGGCCTTGCGGTCACCGC
TGTCGGTCAAACCGGCGTCC

Product: putative metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLQYLTVPVTAFQQNCSIVWCDATRRAAVIDPGGELPRLRAEVRRLGLTLEAIWLTHAHIDHAGGTAQLAREDALPIIGP
HAADQFWIDGLAQQSRMFGFPPSEPFTPTRWLCPGGVDDRVTLGDCELEVRHCPGHTPGHVVFVSREAQRAFVGDVLFAG
GIGRTDFPLGDHDTLVAAIRTQLWPLGDDIVFIPGHGPESSFGRERRHNPYVRDV

Sequences:

>Translated_215_residues
MLQYLTVPVTAFQQNCSIVWCDATRRAAVIDPGGELPRLRAEVRRLGLTLEAIWLTHAHIDHAGGTAQLAREDALPIIGP
HAADQFWIDGLAQQSRMFGFPPSEPFTPTRWLCPGGVDDRVTLGDCELEVRHCPGHTPGHVVFVSREAQRAFVGDVLFAG
GIGRTDFPLGDHDTLVAAIRTQLWPLGDDIVFIPGHGPESSFGRERRHNPYVRDV
>Mature_215_residues
MLQYLTVPVTAFQQNCSIVWCDATRRAAVIDPGGELPRLRAEVRRLGLTLEAIWLTHAHIDHAGGTAQLAREDALPIIGP
HAADQFWIDGLAQQSRMFGFPPSEPFTPTRWLCPGGVDDRVTLGDCELEVRHCPGHTPGHVVFVSREAQRAFVGDVLFAG
GIGRTDFPLGDHDTLVAAIRTQLWPLGDDIVFIPGHGPESSFGRERRHNPYVRDV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI116642887, Length=197, Percent_Identity=31.4720812182741, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI41327741, Length=197, Percent_Identity=30.4568527918782, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI21703352, Length=197, Percent_Identity=31.4720812182741, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1787158, Length=213, Percent_Identity=52.5821596244132, Blast_Score=253, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23699; Mature: 23699

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQYLTVPVTAFQQNCSIVWCDATRRAAVIDPGGELPRLRAEVRRLGLTLEAIWLTHAHI
CCEEEEECHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEEE
DHAGGTAQLAREDALPIIGPHAADQFWIDGLAQQSRMFGFPPSEPFTPTRWLCPGGVDDR
ECCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCC
VTLGDCELEVRHCPGHTPGHVVFVSREAQRAFVGDVLFAGGIGRTDFPLGDHDTLVAAIR
EEECCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHHHH
TQLWPLGDDIVFIPGHGPESSFGRERRHNPYVRDV
HHHCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MLQYLTVPVTAFQQNCSIVWCDATRRAAVIDPGGELPRLRAEVRRLGLTLEAIWLTHAHI
CCEEEEECHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHCCEEEEEEEEEEEE
DHAGGTAQLAREDALPIIGPHAADQFWIDGLAQQSRMFGFPPSEPFTPTRWLCPGGVDDR
ECCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCC
VTLGDCELEVRHCPGHTPGHVVFVSREAQRAFVGDVLFAGGIGRTDFPLGDHDTLVAAIR
EEECCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHHHH
TQLWPLGDDIVFIPGHGPESSFGRERRHNPYVRDV
HHHCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]