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The map label for this gene is ybeM [H]

Identifier: 124028507

GI number: 124028507

Start: 1659281

End: 1660090

Strand: Direct

Name: ybeM [H]

Synonym: Hbut_1669

Alternate gene names: 124028507

Gene position: 1659281-1660090 (Clockwise)

Preceding gene: 124028504

Following gene: NA

Centisome position: 99.53

GC content: 54.94

Gene sequence:

>810_bases
TTGCAAACACTCACCATAGCCCTACTACAGTTTGGCGCTACACACTCGAAAGAAGAGAGCCTCGAGAGGATAAGAAAGCT
CATTTCGCGCTACGAGAGAATAGTCTCCGAGGCGGATCTCCTACTAGTCCCCGAGTACTCCATGGCAGACCCTACAGGCC
AGCCACCCGAGGCGATAGCAGCTATAGCAGAGCCCCTCGAAGGGCCCTGGATAGGCTTCTTTGCCAGGCTCGCGAGAGAG
TACAGCGTCCACGTGGTTGCAACACTCTACGAGAAAAGCAAGGCCGGAGGAAAACCATACAATACCGCGGCGCTGATCGC
GCCTACTGGCGAGCTCCTAGCAGTATACCGTAAGATACACCTCTTTGACGCCTATGGCTACCGAGAGTCGGACTATTTTA
TGCCAGGCGCAGAACCAGCAAAACTGGCAACCATCAAGGGATTTCGCATAGCTCTAGCGGTATGCTTCGACCTACGCTTC
CCAGAGCTATTCAGGACATATGCCCTGCAGGGAGCGGAGCTAGTAGCAGTCCCAGCAGCATGGTACCGGGGCCCCGCAAA
GGAGGACCAGCTCCGAATAATCGCTGCGGCAAGGGCGCACGAAAACACAATGTACATAGCGGTAGCCTCACAGTACAATA
GCAACTTTACAGGTAGAAGCCTGGTAGCAGACCCCTACGGCCTCGTACTCCTCGATGCAGGCCGTGGAGAGAAGATAGTC
CAGATAGAGGTAGATAGGGAATCCCTTGAGGAGGCGCGCAGACAACTCCCACTACTCAAGCTACGCAGGCCACACGCATA
CAAGCTCTAA

Upstream 100 bases:

>100_bases
ATCCAAAGCCCAAGCTTCACCGTAAACAGCTGCTCTAGCGGGAGAAATTTACGCATACCGAGCCCCGGGAAGACATACAC
ATGGCTGAGGGCGGCACGCA

Downstream 100 bases:

>100_bases
CAGCTATCACGGTCAGGCCACACGACAACATATCCACCGGAAAAACCTCCACGAACCCGCCTCTTCTCCTCAGCAGACCG
TAGAACATACTCCAACCCAT

Product: amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MQTLTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIAEPLEGPWIGFFARLARE
YSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRF
PELFRTYALQGAELVAVPAAWYRGPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIV
QIEVDRESLEEARRQLPLLKLRRPHAYKL

Sequences:

>Translated_269_residues
MQTLTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIAEPLEGPWIGFFARLARE
YSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRF
PELFRTYALQGAELVAVPAAWYRGPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIV
QIEVDRESLEEARRQLPLLKLRRPHAYKL
>Mature_269_residues
MQTLTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIAEPLEGPWIGFFARLARE
YSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRF
PELFRTYALQGAELVAVPAAWYRGPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIV
QIEVDRESLEEARRQLPLLKLRRPHAYKL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=281, Percent_Identity=32.0284697508897, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI297632350, Length=281, Percent_Identity=29.8932384341637, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI297632348, Length=281, Percent_Identity=29.8932384341637, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI5031947, Length=281, Percent_Identity=29.8932384341637, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI297632346, Length=195, Percent_Identity=30.2564102564103, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=276, Percent_Identity=25, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323383, Length=281, Percent_Identity=29.1814946619217, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322335, Length=302, Percent_Identity=24.5033112582781, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355835, Length=206, Percent_Identity=29.126213592233, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17933642, Length=282, Percent_Identity=29.7872340425532, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30073; Mature: 30073

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIA
CCHHEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHH
AIAEPLEGPWIGFFARLAREYSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIH
HHHHCCCCCHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCCEEEEECCHHHHHHHHHHH
LFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAA
HEECCCCCCCCCCCCCCCCCCEEEECHHHEEEHHHHHCCCHHHHHHHHCCCCEEEEECHH
WYRGPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIV
HHCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCEEE
QIEVDRESLEEARRQLPLLKLRRPHAYKL
EEEECHHHHHHHHHCCCCEECCCCCCCCC
>Mature Secondary Structure
MQTLTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIA
CCHHEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHH
AIAEPLEGPWIGFFARLAREYSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIH
HHHHCCCCCHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCCEEEEECCHHHHHHHHHHH
LFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAA
HEECCCCCCCCCCCCCCCCCCEEEECHHHEEEHHHHHCCCHHHHHHHHCCCCEEEEECHH
WYRGPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIV
HHCCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCEEE
QIEVDRESLEEARRQLPLLKLRRPHAYKL
EEEECHHHHHHHHHCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]