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The map label for this gene is 124028436

Identifier: 124028436

GI number: 124028436

Start: 1600552

End: 1601244

Strand: Reverse

Name: 124028436

Synonym: Hbut_1592

Alternate gene names: NA

Gene position: 1601244-1600552 (Counterclockwise)

Preceding gene: 124028456

Following gene: 124028435

Centisome position: 96.05

GC content: 56.71

Gene sequence:

>693_bases
ATGCAGCGGCCCAGGATAAAGCTGGTGCTCGCTGAAGCCGCCCTAGAGACTGTGCCCCGGGAGATATGGGGTCACCCTGC
AGTCTACAAGACGGCAAAGCGTCGCGGCAAGACCCCAGCAAGCATACTGCTTGACCGGAGCCTACACCACCAGGCCATGA
AGGGTCTACCCGAGGCGGAGAAGAGGGGGCGGCCGGACATAGTCCACATATCGCTCCTCGAAGCGCTTAGCAGCCCGCTA
AACCGCGAGGGTCTCCTCGAAACCTATGTGCACACCATAGGCGACTATGCAATATTCATAAAGCCCGAGACTAGGCTCCC
GAGAAACTATAACCGGTTCGTAGGCCTCATAGAGCAGCTCTTCGAGATAGGTAGGGTGCCCCCCGAGGGAGAGCCGCTAC
TCACACTGAAGCCTATGAGTCTTCGCGTACTCCTTGAAACAATCCAGCCCACGAAGATTATATTGTTAGCAGAGGATGGT
GAGCCCCGGCGGCTGAGAGAGATCGCGATAGAGCTAGCCCGCGAGGTGGCACCAGCAGTGATAGTAGGAGCCTTCCCTCA
CGGGGACTTCCGCCCGGAGAATAAGAAGCTAGCAGATGGTATCTACAGCATATACGGTGGGAAGCCCCTTGAAACCTGGA
CAGTAGTATCACACCTCCTGGCAATCCTTGCAGACCACCTAGGCATAGTATAG

Upstream 100 bases:

>100_bases
GTACGGATGGCCTGTAGTGCGACATCCCTAGCAAGCTCTCTGGACTTAGCTTTTGAACCAGACACCGGCCCCGAAACCCC
TAGCTGGGTAGGGTAGAGCC

Downstream 100 bases:

>100_bases
GGTGGCAAGGCATGATGTCATCATACTTTACTCCTCTTGAAACAGATCCGGCATTAACTCTGTTAAGTACAGTCGTACTA
GCATCAATAGTCTTCCTGCT

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MQRPRIKLVLAEAALETVPREIWGHPAVYKTAKRRGKTPASILLDRSLHHQAMKGLPEAEKRGRPDIVHISLLEALSSPL
NREGLLETYVHTIGDYAIFIKPETRLPRNYNRFVGLIEQLFEIGRVPPEGEPLLTLKPMSLRVLLETIQPTKIILLAEDG
EPRRLREIAIELAREVAPAVIVGAFPHGDFRPENKKLADGIYSIYGGKPLETWTVVSHLLAILADHLGIV

Sequences:

>Translated_230_residues
MQRPRIKLVLAEAALETVPREIWGHPAVYKTAKRRGKTPASILLDRSLHHQAMKGLPEAEKRGRPDIVHISLLEALSSPL
NREGLLETYVHTIGDYAIFIKPETRLPRNYNRFVGLIEQLFEIGRVPPEGEPLLTLKPMSLRVLLETIQPTKIILLAEDG
EPRRLREIAIELAREVAPAVIVGAFPHGDFRPENKKLADGIYSIYGGKPLETWTVVSHLLAILADHLGIV
>Mature_230_residues
MQRPRIKLVLAEAALETVPREIWGHPAVYKTAKRRGKTPASILLDRSLHHQAMKGLPEAEKRGRPDIVHISLLEALSSPL
NREGLLETYVHTIGDYAIFIKPETRLPRNYNRFVGLIEQLFEIGRVPPEGEPLLTLKPMSLRVLLETIQPTKIILLAEDG
EPRRLREIAIELAREVAPAVIVGAFPHGDFRPENKKLADGIYSIYGGKPLETWTVVSHLLAILADHLGIV

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing [H]

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family [H]

Homologues:

Organism=Homo sapiens, GI194328699, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323215, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005304 [H]

Pfam domain/function: PF03587 EMG1 [H]

EC number: NA

Molecular weight: Translated: 25778; Mature: 25778

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPRIKLVLAEAALETVPREIWGHPAVYKTAKRRGKTPASILLDRSLHHQAMKGLPEAE
CCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
KRGRPDIVHISLLEALSSPLNREGLLETYVHTIGDYAIFIKPETRLPRNYNRFVGLIEQL
HCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHH
FEIGRVPPEGEPLLTLKPMSLRVLLETIQPTKIILLAEDGEPRRLREIAIELAREVAPAV
HHHCCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCEE
IVGAFPHGDFRPENKKLADGIYSIYGGKPLETWTVVSHLLAILADHLGIV
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRPRIKLVLAEAALETVPREIWGHPAVYKTAKRRGKTPASILLDRSLHHQAMKGLPEAE
CCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
KRGRPDIVHISLLEALSSPLNREGLLETYVHTIGDYAIFIKPETRLPRNYNRFVGLIEQL
HCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHH
FEIGRVPPEGEPLLTLKPMSLRVLLETIQPTKIILLAEDGEPRRLREIAIELAREVAPAV
HHHCCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCEE
IVGAFPHGDFRPENKKLADGIYSIYGGKPLETWTVVSHLLAILADHLGIV
EEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA