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The map label for this gene is helC [H]

Identifier: 124028359

GI number: 124028359

Start: 1517403

End: 1518533

Strand: Reverse

Name: helC [H]

Synonym: Hbut_1512

Alternate gene names: 124028359

Gene position: 1518533-1517403 (Counterclockwise)

Preceding gene: 124028360

Following gene: 124028358

Centisome position: 91.08

GC content: 59.59

Gene sequence:

>1131_bases
TTGCACCTGGATTGGGAGGACGCTACAGCTGTGCTGTTGCGGGGTGACTCCCGGGCCTTGGCTGGTAGTGTTGGTAGGCT
CGTGGGGTTTCTCGCTACGCTGCTAATTGTTGACGCTTTGGTGTCGGCTTATGCAGTACTGGAGGGGTCCTATCCTGCCT
TTGTGCCTCTGGGAAGCCCTGCTGCCTACCTCAACATCTACATCCATGTGCCGACAGCTATGGTCAGCTATGTACTCTAC
ACTGGCGCGTTTGTCTCGGCTATACTCTACCTGCTCCGCCGGCGCCAAGTCTATGATAGGTATGTTGTTGGGTTCCTGAT
CGTTGCAACGCTTTACGCCGCCTACACGCTTGTCTCGGGCAGCTTCTGGGCAGCCGAGTCCTGGGGGAAGGCGTGGAACT
GGGATCCCCGCGAGACGGGCGTCCTCCTACTCTTCCTAGTCTACCTGGTCTACTTTGCGCTCCGGGCCAGCATAACCGAC
CCCGACAGGGCCCCAGTGGTTTCCTCGGTCTACGCCGTTGCCGCCTATGCAATGGTGCCGATTAGCTATGCTGCGCCCCG
TATAGCGGAGTCGAGCCTGCATCCCACACAAGCGCTCCTCCAGGATTTCATGCAGGATCCAGCGGTTCGGGCGATATTCT
ACTCGAAGATACTGCTGGTCCTCGCTATAGGCTTGCTATCGGTGCAGGCCTATGTGCGGGCTGCTGGAGCCGGCGTAGAG
TATGCCAGGAGGCTCAGGCTAGCAGGCATTGCGGCCGGCTTGATAATAGTGGCTACAGCAGTCTACATGGCCACCGGCTA
CCTCGGCGGCACCGTTACAAGGGTATACGGTGTCTTCCCCTCAGGGAACGGTGTAGTGCTCACCGTGAGGCTTAGCGGGG
GCTTCGTCAACATAACCTACACCGGGCCCATCGACAAGTACCTGGTTGACGGCAAGGTAGCGCTCCAGGGCCACGTGGTG
AGGCTAGGGGGCCTCTCGGCCACTGTCGCATCGGCGCTCTCCGTGCTCCGGCCGGGCTGCGTTATAGTCGACACGCTACT
CTATGGGCTGCTTGTTTCGGGGCTAGCCTATATTGTAGCCCGGAGACTGGTAAGTGGTGGGGCTGGGAATAGTGGCGGCT
GGCAAGGCTAA

Upstream 100 bases:

>100_bases
GGACGGACATCGCCTAGTGGTATGTGGCTATGCTGTCCAGGGGCTCTATCGCCTCCGGATTTTTGCGTGGGTGGCTTTAT
TACCTGGTTCTCGGTGGGCC

Downstream 100 bases:

>100_bases
GCCTATACTCGCAGCAATAGTACTCTTCGCCGCCTTCGCGGTGATAGGCTACTATGCGGTAAAGGGTAGCAGCTACATGG
ATGTCTCGGACGTGGTTAAA

Product: ABC transporter

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein HelC [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MHLDWEDATAVLLRGDSRALAGSVGRLVGFLATLLIVDALVSAYAVLEGSYPAFVPLGSPAAYLNIYIHVPTAMVSYVLY
TGAFVSAILYLLRRRQVYDRYVVGFLIVATLYAAYTLVSGSFWAAESWGKAWNWDPRETGVLLLFLVYLVYFALRASITD
PDRAPVVSSVYAVAAYAMVPISYAAPRIAESSLHPTQALLQDFMQDPAVRAIFYSKILLVLAIGLLSVQAYVRAAGAGVE
YARRLRLAGIAAGLIIVATAVYMATGYLGGTVTRVYGVFPSGNGVVLTVRLSGGFVNITYTGPIDKYLVDGKVALQGHVV
RLGGLSATVASALSVLRPGCVIVDTLLYGLLVSGLAYIVARRLVSGGAGNSGGWQG

Sequences:

>Translated_376_residues
MHLDWEDATAVLLRGDSRALAGSVGRLVGFLATLLIVDALVSAYAVLEGSYPAFVPLGSPAAYLNIYIHVPTAMVSYVLY
TGAFVSAILYLLRRRQVYDRYVVGFLIVATLYAAYTLVSGSFWAAESWGKAWNWDPRETGVLLLFLVYLVYFALRASITD
PDRAPVVSSVYAVAAYAMVPISYAAPRIAESSLHPTQALLQDFMQDPAVRAIFYSKILLVLAIGLLSVQAYVRAAGAGVE
YARRLRLAGIAAGLIIVATAVYMATGYLGGTVTRVYGVFPSGNGVVLTVRLSGGFVNITYTGPIDKYLVDGKVALQGHVV
RLGGLSATVASALSVLRPGCVIVDTLLYGLLVSGLAYIVARRLVSGGAGNSGGWQG
>Mature_376_residues
MHLDWEDATAVLLRGDSRALAGSVGRLVGFLATLLIVDALVSAYAVLEGSYPAFVPLGSPAAYLNIYIHVPTAMVSYVLY
TGAFVSAILYLLRRRQVYDRYVVGFLIVATLYAAYTLVSGSFWAAESWGKAWNWDPRETGVLLLFLVYLVYFALRASITD
PDRAPVVSSVYAVAAYAMVPISYAAPRIAESSLHPTQALLQDFMQDPAVRAIFYSKILLVLAIGLLSVQAYVRAAGAGVE
YARRLRLAGIAAGLIIVATAVYMATGYLGGTVTRVYGVFPSGNGVVLTVRLSGGFVNITYTGPIDKYLVDGKVALQGHVV
RLGGLSATVASALSVLRPGCVIVDTLLYGLLVSGLAYIVARRLVSGGAGNSGGWQG

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 39965; Mature: 39965

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLDWEDATAVLLRGDSRALAGSVGRLVGFLATLLIVDALVSAYAVLEGSYPAFVPLGSP
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
AAYLNIYIHVPTAMVSYVLYTGAFVSAILYLLRRRQVYDRYVVGFLIVATLYAAYTLVSG
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFWAAESWGKAWNWDPRETGVLLLFLVYLVYFALRASITDPDRAPVVSSVYAVAAYAMVP
CCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ISYAAPRIAESSLHPTQALLQDFMQDPAVRAIFYSKILLVLAIGLLSVQAYVRAAGAGVE
HHHCCCHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YARRLRLAGIAAGLIIVATAVYMATGYLGGTVTRVYGVFPSGNGVVLTVRLSGGFVNITY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHEEECCCCCCEEEEEEECCCEEEEEE
TGPIDKYLVDGKVALQGHVVRLGGLSATVASALSVLRPGCVIVDTLLYGLLVSGLAYIVA
ECCCHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRLVSGGAGNSGGWQG
HHHHCCCCCCCCCCCC
>Mature Secondary Structure
MHLDWEDATAVLLRGDSRALAGSVGRLVGFLATLLIVDALVSAYAVLEGSYPAFVPLGSP
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
AAYLNIYIHVPTAMVSYVLYTGAFVSAILYLLRRRQVYDRYVVGFLIVATLYAAYTLVSG
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFWAAESWGKAWNWDPRETGVLLLFLVYLVYFALRASITDPDRAPVVSSVYAVAAYAMVP
CCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ISYAAPRIAESSLHPTQALLQDFMQDPAVRAIFYSKILLVLAIGLLSVQAYVRAAGAGVE
HHHCCCHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YARRLRLAGIAAGLIIVATAVYMATGYLGGTVTRVYGVFPSGNGVVLTVRLSGGFVNITY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHEEECCCCCCEEEEEEECCCEEEEEE
TGPIDKYLVDGKVALQGHVVRLGGLSATVASALSVLRPGCVIVDTLLYGLLVSGLAYIVA
ECCCHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRLVSGGAGNSGGWQG
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1310666 [H]