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The map label for this gene is hmeD [H]

Identifier: 124028219

GI number: 124028219

Start: 1360198

End: 1361658

Strand: Reverse

Name: hmeD [H]

Synonym: Hbut_1369

Alternate gene names: 124028219

Gene position: 1361658-1360198 (Counterclockwise)

Preceding gene: 124028220

Following gene: 124028218

Centisome position: 81.68

GC content: 52.5

Gene sequence:

>1461_bases
ATGGCCGCGACAGGTAGCCCCGTGGCACGCGATATAGCTATGAAGGTGAGGGAGAGAATTTCCTGGAGCGGCTTTGACAA
GGCGAAACTGGATAGGGCTGTAGCCAAGTTTGTGGGCAGGATAGATGTCGTCAAGCTACACTTCCTAGAGGCGTGCGTTG
GCTGTGGTGTATGTGCACCAGCATGTCCATACTACTATGTAGATGAGCGGAATGCACCGATGATTAAGGCTGAAAAGGCA
CGCTACATATACCGTAAGAAGCTAACGTTTGCTGGTAGGATACTTGGCTGGCTAGTGAACGCCAAGCTTCCAAAGAGCGA
GAAGGATCTTGACGAGATTGTAGAGGCTGTGTATCGGTGTACAAACTGTGGCCACTGCTACCTGACATGTCCGTTCGGAA
TTGACAGTGGTAGTGTGATCCAGGAGCTGTTAAAGATTGTGGCCACTGATATGGGTAGAGTGCCATCCCTCATAGACTTC
TTCGCCGAGCTAGAGAGGAGCGGAGCATTCTACGAGGTTCCAAGCCTTATGGAGGCTTGGAAGGCTGCACTAACCAAGGC
TGAGGAGGCTATCGGGAAGAAGCTGCCATACGATAAGGCTGGCGCGGAGATACTACTACTGCCAATGCTGACAGACGCAC
TATTCTACCCCGGAGCCATCGCTGGCGCCATAAAGATCCTAGAGGCTGCCAAGCTAGACTACACAGTGCCCAGCAAGCCA
CTGGGCTTTAGAACGCCGGTAGCCGCTGTAGCCGGAAGACCGGAAGCTGCCAAGGAAGCTCTCAAGAGGCTCGTTGACAG
CATTGAAAAGCTCGGCGTAAAGACTGTAGTATTGCTGGACGGCGGCTTCCCCTATTTCTGGCTGCGTTGGAAGGCGCCAA
CAGTCCTTGGCAGAAAGCTCGATTTCAAGGTGCTCCACATAGTAGAGCTTGTCGACGAGCTAATTTCAAAGGGTAAGTTG
GAGTTCGAGACGGCAGACGACGAGGTAACATGGCATGATCCGTGCCAGCTTGTCCGGAGGGGAGGTGTGGTAGAGGAACC
CTACAGGGTCATGGCGAAGGTTAGCAGAAGGTTTAGGCCACTACCCCATCATGGCGTAAACAGTCTATGCTGTGGCGGTG
GAGGAGGCATAGGCTGTATGAGCATGGAGATGATCAAGCAGTTCTCCAGCCTAGTAGGACTCAAACCCGAGGACCTCATT
AGCGGCGAGAAGGAGAAAGAGTTCATCGAGAAGACCGAGAAGGCGTGGGCCGTAGCACTCAAGAGGAAGATAGACCATAT
ACGTGAGAGTAAGGCGAAGCCTCGTAGTAACAGCTTGCCCGGTCTGCATGCACTCAATTGCTGGCGGTGCAAAGATCTAC
GGTCTCGAAATCGGTATTATGCATATTGCAGAATACCTTGGAAGGTATGTGCGGGGTGTTGGAACCAAATGACAGTTCAT
GACCCGTACACGGTTTTTTGA

Upstream 100 bases:

>100_bases
CTGGCACTTTGTGTTTGGCTACTGGTATGGCGAGATCCACAAGTATTGGGATGTGAAGGTGCGTAAGGGTGTAGTGTAAG
CTGCAGGGAGGTGGTAGCCT

Downstream 100 bases:

>100_bases
CAACACAAACCCCGGCTGAGCACAGTGACGAGGGGTGCACACAATGACACGTACATCACGCACAATTAGGATCCATATAG
ACCCTATAACGAGGATTGAG

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MAATGSPVARDIAMKVRERISWSGFDKAKLDRAVAKFVGRIDVVKLHFLEACVGCGVCAPACPYYYVDERNAPMIKAEKA
RYIYRKKLTFAGRILGWLVNAKLPKSEKDLDEIVEAVYRCTNCGHCYLTCPFGIDSGSVIQELLKIVATDMGRVPSLIDF
FAELERSGAFYEVPSLMEAWKAALTKAEEAIGKKLPYDKAGAEILLLPMLTDALFYPGAIAGAIKILEAAKLDYTVPSKP
LGFRTPVAAVAGRPEAAKEALKRLVDSIEKLGVKTVVLLDGGFPYFWLRWKAPTVLGRKLDFKVLHIVELVDELISKGKL
EFETADDEVTWHDPCQLVRRGGVVEEPYRVMAKVSRRFRPLPHHGVNSLCCGGGGGIGCMSMEMIKQFSSLVGLKPEDLI
SGEKEKEFIEKTEKAWAVALKRKIDHIRESKAKPRSNSLPGLHALNCWRCKDLRSRNRYYAYCRIPWKVCAGCWNQMTVH
DPYTVF

Sequences:

>Translated_486_residues
MAATGSPVARDIAMKVRERISWSGFDKAKLDRAVAKFVGRIDVVKLHFLEACVGCGVCAPACPYYYVDERNAPMIKAEKA
RYIYRKKLTFAGRILGWLVNAKLPKSEKDLDEIVEAVYRCTNCGHCYLTCPFGIDSGSVIQELLKIVATDMGRVPSLIDF
FAELERSGAFYEVPSLMEAWKAALTKAEEAIGKKLPYDKAGAEILLLPMLTDALFYPGAIAGAIKILEAAKLDYTVPSKP
LGFRTPVAAVAGRPEAAKEALKRLVDSIEKLGVKTVVLLDGGFPYFWLRWKAPTVLGRKLDFKVLHIVELVDELISKGKL
EFETADDEVTWHDPCQLVRRGGVVEEPYRVMAKVSRRFRPLPHHGVNSLCCGGGGGIGCMSMEMIKQFSSLVGLKPEDLI
SGEKEKEFIEKTEKAWAVALKRKIDHIRESKAKPRSNSLPGLHALNCWRCKDLRSRNRYYAYCRIPWKVCAGCWNQMTVH
DPYTVF
>Mature_485_residues
AATGSPVARDIAMKVRERISWSGFDKAKLDRAVAKFVGRIDVVKLHFLEACVGCGVCAPACPYYYVDERNAPMIKAEKAR
YIYRKKLTFAGRILGWLVNAKLPKSEKDLDEIVEAVYRCTNCGHCYLTCPFGIDSGSVIQELLKIVATDMGRVPSLIDFF
AELERSGAFYEVPSLMEAWKAALTKAEEAIGKKLPYDKAGAEILLLPMLTDALFYPGAIAGAIKILEAAKLDYTVPSKPL
GFRTPVAAVAGRPEAAKEALKRLVDSIEKLGVKTVVLLDGGFPYFWLRWKAPTVLGRKLDFKVLHIVELVDELISKGKLE
FETADDEVTWHDPCQLVRRGGVVEEPYRVMAKVSRRFRPLPHHGVNSLCCGGGGGIGCMSMEMIKQFSSLVGLKPEDLIS
GEKEKEFIEKTEKAWAVALKRKIDHIRESKAKPRSNSLPGLHALNCWRCKDLRSRNRYYAYCRIPWKVCAGCWNQMTVHD
PYTVF

Specific function: Has menaquinol-oxidizing activity. HmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54316; Mature: 54185

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATGSPVARDIAMKVRERISWSGFDKAKLDRAVAKFVGRIDVVKLHFLEACVGCGVCAP
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ACPYYYVDERNAPMIKAEKARYIYRKKLTFAGRILGWLVNAKLPKSEKDLDEIVEAVYRC
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
TNCGHCYLTCPFGIDSGSVIQELLKIVATDMGRVPSLIDFFAELERSGAFYEVPSLMEAW
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECHHHHHHH
KAALTKAEEAIGKKLPYDKAGAEILLLPMLTDALFYPGAIAGAIKILEAAKLDYTVPSKP
HHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
LGFRTPVAAVAGRPEAAKEALKRLVDSIEKLGVKTVVLLDGGFPYFWLRWKAPTVLGRKL
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHCCCC
DFKVLHIVELVDELISKGKLEFETADDEVTWHDPCQLVRRGGVVEEPYRVMAKVSRRFRP
CHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCC
LPHHGVNSLCCGGGGGIGCMSMEMIKQFSSLVGLKPEDLISGEKEKEFIEKTEKAWAVAL
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
KRKIDHIRESKAKPRSNSLPGLHALNCWRCKDLRSRNRYYAYCRIPWKVCAGCWNQMTVH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCEEC
DPYTVF
CCCCCC
>Mature Secondary Structure 
AATGSPVARDIAMKVRERISWSGFDKAKLDRAVAKFVGRIDVVKLHFLEACVGCGVCAP
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
ACPYYYVDERNAPMIKAEKARYIYRKKLTFAGRILGWLVNAKLPKSEKDLDEIVEAVYRC
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
TNCGHCYLTCPFGIDSGSVIQELLKIVATDMGRVPSLIDFFAELERSGAFYEVPSLMEAW
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECHHHHHHH
KAALTKAEEAIGKKLPYDKAGAEILLLPMLTDALFYPGAIAGAIKILEAAKLDYTVPSKP
HHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
LGFRTPVAAVAGRPEAAKEALKRLVDSIEKLGVKTVVLLDGGFPYFWLRWKAPTVLGRKL
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCHHHCCCC
DFKVLHIVELVDELISKGKLEFETADDEVTWHDPCQLVRRGGVVEEPYRVMAKVSRRFRP
CHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCC
LPHHGVNSLCCGGGGGIGCMSMEMIKQFSSLVGLKPEDLISGEKEKEFIEKTEKAWAVAL
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHH
KRKIDHIRESKAKPRSNSLPGLHALNCWRCKDLRSRNRYYAYCRIPWKVCAGCWNQMTVH
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCEEC
DPYTVF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]