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The map label for this gene is rpl3p [H]

Identifier: 124028157

GI number: 124028157

Start: 1308395

End: 1309354

Strand: Direct

Name: rpl3p [H]

Synonym: Hbut_1302

Alternate gene names: 124028157

Gene position: 1308395-1309354 (Clockwise)

Preceding gene: 124028156

Following gene: 124028158

Centisome position: 78.48

GC content: 53.65

Gene sequence:

>960_bases
GTGAAGAGTTGGCCGGAGGTTCAGAGCGAGAACCCGCTGCCGCTTGCATTCCTGGCATACAAGGTTGGCATGACACATGT
ATATGTAATAGATGATGAGCCGGGCTCAATAACCCATGGTAGAGAAATATTCATGCCCGTCACAGTACTCGAAGCGCCAC
CAATGGTTGTCACAGCGGTAAGAGTCTACGGCTATGATCCCAACATAGGCCTATACACGCTCAGTGAGGCATGGGCTCAG
CCCGAGACGCTCGTGGAAAAGTACAACCTTGACATATACCGTGTAGTTCCAAGGCTACGCTTCCCAGACCCGGACAAGGC
TGTTAAGAAGCTTGAGGGCCTACTAGACAAGGTCTATGATGTCCGCATCATAGCAGCTACACAGCCTAGGCTCGTTGGCG
GTCTCAGCAAGAAGAAGCCAGACCTACTAGAGATAAAGATCGGTGGCGGCAGCAGCATAGAGGACCGCTTCAACTATGCA
GTTAAGCTGCTAGGCTCGGAGCTAAAGGTCTCCGATGTATTCCGCGAGGGGCAGTTTGTAGATGTTATAGCTGTGACTAA
GGGTAAGGGCTTCCAGGGTGTAATCAAGAGGTTTGGTGTCAAGGAGCTGCCGAGATGGCACAAGCACAGGAAGGGTAGCA
GGAGCGGCCCCGGTACAAGAGGTCCAGCAACATCATTCTCGTGGAGCGAGGTGCCACAGCCAGGCCAGATGGGCTTCCAC
CGCAGGACAGAGTACAACAAGCGCATACTAAAGATAGGCGACAACGGCCTCGAAATCACCCCAGCGGGCGGCTTCCTACA
CTACGGCATTGTTAGGAGCACCTACATACTGCTAGCAGGCAGTATACCGGGTACACCTAAGAGGCCAATAGTGCTGAGGC
ACCCGGTAAGGCCACGCTGGATGCCGGAGGCACCACCAAAGATAACATACATAAGCCTTGCAAGCAAGCAGGGCAACTAG

Upstream 100 bases:

>100_bases
TAGGCGGTGATGCATAGTGGGTGCACGAAAAAAGCATGCGCCTCGACGTGGAAGCTTAGGACTCCGGCCGCGTAAGCGTG
CCTCGAGGCTAGTGCCTAGA

Downstream 100 bases:

>100_bases
CCTAGGGCGCACCAATCGGTGAACGTGTGGGCCAGGAGGTGTAGGCGTTGGCGTCGAAGATAGGCTCAATGATATTCCTG
CTTGCGACACAGCCGCCTCG

Product: 50S ribosomal protein L3P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKSWPEVQSENPLPLAFLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMVVTAVRVYGYDPNIGLYTLSEAWAQ
PETLVEKYNLDIYRVVPRLRFPDPDKAVKKLEGLLDKVYDVRIIAATQPRLVGGLSKKKPDLLEIKIGGGSSIEDRFNYA
VKLLGSELKVSDVFREGQFVDVIAVTKGKGFQGVIKRFGVKELPRWHKHRKGSRSGPGTRGPATSFSWSEVPQPGQMGFH
RRTEYNKRILKIGDNGLEITPAGGFLHYGIVRSTYILLAGSIPGTPKRPIVLRHPVRPRWMPEAPPKITYISLASKQGN

Sequences:

>Translated_319_residues
MKSWPEVQSENPLPLAFLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMVVTAVRVYGYDPNIGLYTLSEAWAQ
PETLVEKYNLDIYRVVPRLRFPDPDKAVKKLEGLLDKVYDVRIIAATQPRLVGGLSKKKPDLLEIKIGGGSSIEDRFNYA
VKLLGSELKVSDVFREGQFVDVIAVTKGKGFQGVIKRFGVKELPRWHKHRKGSRSGPGTRGPATSFSWSEVPQPGQMGFH
RRTEYNKRILKIGDNGLEITPAGGFLHYGIVRSTYILLAGSIPGTPKRPIVLRHPVRPRWMPEAPPKITYISLASKQGN
>Mature_319_residues
MKSWPEVQSENPLPLAFLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMVVTAVRVYGYDPNIGLYTLSEAWAQ
PETLVEKYNLDIYRVVPRLRFPDPDKAVKKLEGLLDKVYDVRIIAATQPRLVGGLSKKKPDLLEIKIGGGSSIEDRFNYA
VKLLGSELKVSDVFREGQFVDVIAVTKGKGFQGVIKRFGVKELPRWHKHRKGSRSGPGTRGPATSFSWSEVPQPGQMGFH
RRTEYNKRILKIGDNGLEITPAGGFLHYGIVRSTYILLAGSIPGTPKRPIVLRHPVRPRWMPEAPPKITYISLASKQGN

Specific function: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit [H]

COG id: COG0087

COG function: function code J; Ribosomal protein L3

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L3P family [H]

Homologues:

Organism=Homo sapiens, GI4506649, Length=361, Percent_Identity=32.9639889196676, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI76496472, Length=348, Percent_Identity=31.0344827586207, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI4826988, Length=361, Percent_Identity=32.409972299169, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71984538, Length=358, Percent_Identity=32.6815642458101, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71984544, Length=345, Percent_Identity=29.8550724637681, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71984550, Length=224, Percent_Identity=34.375, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324637, Length=345, Percent_Identity=33.0434782608696, Blast_Score=136, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24645877, Length=361, Percent_Identity=32.9639889196676, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24645879, Length=361, Percent_Identity=32.9639889196676, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI17737907, Length=361, Percent_Identity=32.9639889196676, Blast_Score=164, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000597
- InterPro:   IPR019928
- InterPro:   IPR019926
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00297 Ribosomal_L3 [H]

EC number: NA

Molecular weight: Translated: 35609; Mature: 35609

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00474 RIBOSOMAL_L3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSWPEVQSENPLPLAFLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMVVTAV
CCCCCCCCCCCCCCHHHHEEHHCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEE
RVYGYDPNIGLYTLSEAWAQPETLVEKYNLDIYRVVPRLRFPDPDKAVKKLEGLLDKVYD
EEEECCCCCCEEECHHHHCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHE
VRIIAATQPRLVGGLSKKKPDLLEIKIGGGSSIEDRFNYAVKLLGSELKVSDVFREGQFV
EEEEEECCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEE
DVIAVTKGKGFQGVIKRFGVKELPRWHKHRKGSRSGPGTRGPATSFSWSEVPQPGQMGFH
EEEEEECCCCHHHHHHHCCHHHCHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
RRTEYNKRILKIGDNGLEITPAGGFLHYGIVRSTYILLAGSIPGTPKRPIVLRHPVRPRW
HHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCC
MPEAPPKITYISLASKQGN
CCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MKSWPEVQSENPLPLAFLAYKVGMTHVYVIDDEPGSITHGREIFMPVTVLEAPPMVVTAV
CCCCCCCCCCCCCCHHHHEEHHCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEE
RVYGYDPNIGLYTLSEAWAQPETLVEKYNLDIYRVVPRLRFPDPDKAVKKLEGLLDKVYD
EEEECCCCCCEEECHHHHCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHE
VRIIAATQPRLVGGLSKKKPDLLEIKIGGGSSIEDRFNYAVKLLGSELKVSDVFREGQFV
EEEEEECCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEE
DVIAVTKGKGFQGVIKRFGVKELPRWHKHRKGSRSGPGTRGPATSFSWSEVPQPGQMGFH
EEEEEECCCCHHHHHHHCCHHHCHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
RRTEYNKRILKIGDNGLEITPAGGFLHYGIVRSTYILLAGSIPGTPKRPIVLRHPVRPRW
HHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCC
MPEAPPKITYISLASKQGN
CCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]