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The map label for this gene is fixC [C]

Identifier: 124028114

GI number: 124028114

Start: 1262441

End: 1263805

Strand: Reverse

Name: fixC [C]

Synonym: Hbut_1257

Alternate gene names: 124028114

Gene position: 1263805-1262441 (Counterclockwise)

Preceding gene: 124028116

Following gene: 124028113

Centisome position: 75.81

GC content: 52.16

Gene sequence:

>1365_bases
ATGAAGAATGAGCCCCGCTACGACGTTATAGTCGCCGGCTTGGGACCAGCGGGTAGTGTTGCACTCTGGCACCTAGCTCG
CATGGGCTTCCGCGTTCTAGGTATTGAACGTAACCGACCGGAGAAGCTATGGAGCAAACCATGTGGCGACGCACTCGGAG
CCCACCACATAACTGAGTCACATCTGCCCGAACCTCCCTCTAGCGTGCTTAAGAACCGGGTTACAGCTATTGATATTTAC
TCTCCAAGCGAGGAGGTCCGCTATCGTGTTCACGGTAAAGGCTACATTATTGACCGTACAGCCTTTGGCCGCTGGCTTGT
CGAGGATGCCTTAAACCGTGGCGCCGAGGTTCTCTACGAGACTAGCATACTTGAACCGATAATCTCTGGCGGCAAGGTCA
TCGGGGTTAAGGCAAAGTCTAAGGATGGACGCGTAGTGGAACTGTATGCGAGTCTTGTGATTGAGGCTACCGGATTCTCT
AGGGTTATAAGGCGAAGACTACCACGCGACTGGCCTATCTACGAGGATATAGATCCAAGGGATACCAACATAGCATACCG
CGAGATAATAGAGTATGAAGATTACGAGATCGAAGAACCAAACGTCATAAGGATATACTTGAACCAGGAGATAGCTCCCG
GAGGCTACTGGTGGTTCTTCCCCGAGACGAGCCACCGAAGCAATGTTGGCCTCGGTGTACAGGGAGGCATGGGATATCCG
AGCCCTATGCAGATCTACCGGGAGAAGCTTGTTGAGCATAGCCTCCTAAGGCTAAAACACCGTGTCATAACGGCTGCTGG
TGCGCCGCTACCCACACGCAGGCCGTCGAATACTATGGTCGGGCCAGGTGTCGTCGTAATAGGCGATGCTGGCTACACTG
TAAATCCCATTCACGGTGGAGGCATGGGTTATGGCTTTAGAGCCGCTTATTACGCTGCCAAGGCCTTCGAGGAAGCTTAC
AACAAGGGGCGCTTCGACGAAGAGGCACTGTGGAGCCTAAACACTAGCTACATGAGGTCTATAGGGGCTAAGCAGGCCTC
GCTCGACGTGTTTAGGAGGTTCCTACAGAGGCTAGGTAATGATGATATAGAGTTCGGGATGAAACATAAGCTCATACCAG
AGACAGACGTGCTCTACGCTAGCGAGACAGGGGAGCTAAAACTCTCGGTTATAGAGAAGGCCATGATAGTGCTCCGCGGT
CTCCGTAGGCCGACACTGCTGGCAAAGCTAAAGACTGTAGCAGACTATATGAAGAAAATCAAGGAACTCTACATGCGCTA
CCCTGAGAATCCCTCAGGGCTCAAGCAATGGGTAAGAGAGGTTGAAAACCTCCTAAAAGAGTATGAGGCTAGGCTTGGGA
GCTAG

Upstream 100 bases:

>100_bases
GGCTCGACGGAATCGTAGCCTCCAACGTTTGGGGGTAAGGTTAAATGCCGGTTGATGAGGGGAAGTTTCCCGAGCACAAA
ACGCCTGAGGGCCCAGAATC

Downstream 100 bases:

>100_bases
CAGTGTCACTTCAATGGGAGCCTCAGTGGGAGGAGACAATTATAGAGGTCTATGGTGTAAGACTCAAAGTACCACGTGAC
CGCGTAACCGGGCTATATGC

Product: dehydrogenase

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKNEPRYDVIVAGLGPAGSVALWHLARMGFRVLGIERNRPEKLWSKPCGDALGAHHITESHLPEPPSSVLKNRVTAIDIY
SPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYETSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFS
RVIRRRLPRDWPIYEDIDPRDTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP
SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGGGMGYGFRAAYYAAKAFEEAY
NKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGNDDIEFGMKHKLIPETDVLYASETGELKLSVIEKAMIVLRG
LRRPTLLAKLKTVADYMKKIKELYMRYPENPSGLKQWVREVENLLKEYEARLGS

Sequences:

>Translated_454_residues
MKNEPRYDVIVAGLGPAGSVALWHLARMGFRVLGIERNRPEKLWSKPCGDALGAHHITESHLPEPPSSVLKNRVTAIDIY
SPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYETSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFS
RVIRRRLPRDWPIYEDIDPRDTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP
SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGGGMGYGFRAAYYAAKAFEEAY
NKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGNDDIEFGMKHKLIPETDVLYASETGELKLSVIEKAMIVLRG
LRRPTLLAKLKTVADYMKKIKELYMRYPENPSGLKQWVREVENLLKEYEARLGS
>Mature_454_residues
MKNEPRYDVIVAGLGPAGSVALWHLARMGFRVLGIERNRPEKLWSKPCGDALGAHHITESHLPEPPSSVLKNRVTAIDIY
SPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYETSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFS
RVIRRRLPRDWPIYEDIDPRDTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP
SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGGGMGYGFRAAYYAAKAFEEAY
NKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGNDDIEFGMKHKLIPETDVLYASETGELKLSVIEKAMIVLRG
LRRPTLLAKLKTVADYMKKIKELYMRYPENPSGLKQWVREVENLLKEYEARLGS

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 51388; Mature: 51388

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEPRYDVIVAGLGPAGSVALWHLARMGFRVLGIERNRPEKLWSKPCGDALGAHHITES
CCCCCCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCHHHHHHCCCCC
HLPEPPSSVLKNRVTAIDIYSPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYE
CCCCCHHHHHHCCCEEEEEECCCHHCEEEECCCEEEEECHHHHHHHHHHHHCCCHHHHHH
TSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFSRVIRRRLPRDWPIYEDIDPR
HHHHHHHHCCCEEEEEEECCCCCCCCEEEHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
DTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP
CCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCEEECCCCCCC
SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCC
GMGYGFRAAYYAAKAFEEAYNKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGN
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCC
DDIEFGMKHKLIPETDVLYASETGELKLSVIEKAMIVLRGLRRPTLLAKLKTVADYMKKI
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KELYMRYPENPSGLKQWVREVENLLKEYEARLGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNEPRYDVIVAGLGPAGSVALWHLARMGFRVLGIERNRPEKLWSKPCGDALGAHHITES
CCCCCCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCHHHHHHCCCCC
HLPEPPSSVLKNRVTAIDIYSPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYE
CCCCCHHHHHHCCCEEEEEECCCHHCEEEECCCEEEEECHHHHHHHHHHHHCCCHHHHHH
TSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFSRVIRRRLPRDWPIYEDIDPR
HHHHHHHHCCCEEEEEEECCCCCCCCEEEHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
DTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP
CCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCEEECCCCCCC
SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCC
GMGYGFRAAYYAAKAFEEAYNKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGN
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCC
DDIEFGMKHKLIPETDVLYASETGELKLSVIEKAMIVLRGLRRPTLLAKLKTVADYMKKI
CCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KELYMRYPENPSGLKQWVREVENLLKEYEARLGS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA