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The map label for this gene is moaA [C]

Identifier: 124028102

GI number: 124028102

Start: 1250326

End: 1252011

Strand: Reverse

Name: moaA [C]

Synonym: Hbut_1245

Alternate gene names: 124028102

Gene position: 1252011-1250326 (Counterclockwise)

Preceding gene: 124028103

Following gene: 124028099

Centisome position: 75.1

GC content: 47.63

Gene sequence:

>1686_bases
ATGCTATCACTGCACTCAGACCGTCGTAGCGAAACTGACCAGCGGCATGCACAAATACTTGACGCACCTGCAAGGTTTGA
TCCTAAGGCGAAGACCGTTAGTATAGCAGGTAGAACGATACGTATCGGAGGTCCATTACCAAAGCTGAAGGAGAACGAGA
GATTTATAGCATACACGCTTACTGTATGCCCATACTGTTACCGGCTGCTACCAGCAGTAATATTTGAGCGCGGTGGAAAG
GTATACATCAAGAGGAGCTGCCCTGAGCATGGCACCATAGAAGAGCTGTACTTTGGCGACGCCCAGATATACAAGAGATT
CATGAAGTATGAGGAGGAAGGTACTGGCGTTACAGCATACGTAAAGCTTGAAGCGCCATGCCCCTTTAACTGTGGATTAT
GTCCACGCCATAAGAACCATACAGCACTCGCAAATCTGGTTGTAACTAACCGCTGCGACTTATCATGCTGGTATTGCTTC
TTCTACGCCGAGAAGATGGGTTATGTTTATGAGCCAACACTGGAGCAAATAAGGATGATGATAAGACAGTACGCCAAAGA
AGGCGTTGTAATGTCTGTCCAGATAACCGGTGGCGAGCCAACACTAAGGCCAGACCTCCCCGAGATCATTAAGCTGTTGA
AGGAGGAAGGTGTACGCCATATACAGCTCAACACTCACGGCATAACATTTGCAAGGCTATGGTTCGAAAAGGGCCCAGAA
ACAGCTGTAGAGTACGCTAAGAAGCTCCGCGAGGCTGGCCTAAACACAGTTTATATGAGCTTTGACGGTGTTACGCCGCG
TACGAACCCGAAGAACCACTGGGAGGTACCGTATACCCTTGAGGTCTTTAGGAGGGCTGGCGTGACTAGCGTGGTGCTAG
TACCCACTGTGATAAAAGGTATTAACACACATGAACTCGGCGCAATAATAAAGTTCGCTGCCAAACACATGGACGTGATT
AGGGGTGTAAATTATCAGCCCGTCAGCCTCACTGGCAGAATGAGGAAGGAGGAGAGGGAAAAGTACCGGGTAACAATACC
TGATGTGCTAAAGCTTATCGAAGAACAGACAGATGGCCAGATACCAGCTGACGCATGGTTCCCTATACCTGTGGCAGCAA
AGTTTGCATACTTCCTTGAGGCTCTCAGCGGCGAGCTGAAGATATGTATGGCCAACCATCCAGCATGCGGTTCAGCGACA
TACGTTTTCGTAGAGCGTGATGCCGACGGGCTACCTAAGAGGTTTATACCGATAACAGAGTTCTTTGACGTTGAGGGCTT
CATAGAGTACATGGAACAGAAGACCGGAGAGCTAAGAGCAGCTAGAGAGGGAAGGCTTAGTGGGTTCAAACACAAGCTCA
AGATAGCATCAATCATAAAAGATCTACCAAAGTTTGTTGACCGCGAAAAGCTGCCAAAAGACCTCAATATAACTAAGCTG
CTAGCCAATGTGTTCATAAAACGCAACTATGAGGCCCTCGGCGAGCTACACTATAGAATGCTATTCCTCGGCAACATGCA
CTTCATGGACCCATACAACTACGACGTAGAGCGCGTAATGAGGTGCAATATCCACTACCTATCACCGGACGGTAGAATAA
TACCATTCTGTACATATAACGTGTTCACGACCTTTACCGCGACCATATCATTAGGAAGTACGGAATACCAATTGAAGAAT
ACGTAA

Upstream 100 bases:

>100_bases
TACGGGTTTCTTAAACAAGTGTTAGTTTCAAGCACTGATATCTTTTTAACAGTCGTCAAGGGGTATACTCTATTTGAGGC
TTCAAGAGGGGCAAGTGGAC

Downstream 100 bases:

>100_bases
GAAAGTATGGCGGCAAGGATATAGGGCCCGACATCAAGTATGTACGCAACATTAAGCTGCTAAAGAGCACACCAATATAT
TACGAGGCATACAAGGGTAT

Product: Fe-S osidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MLSLHSDRRSETDQRHAQILDAPARFDPKAKTVSIAGRTIRIGGPLPKLKENERFIAYTLTVCPYCYRLLPAVIFERGGK
VYIKRSCPEHGTIEELYFGDAQIYKRFMKYEEEGTGVTAYVKLEAPCPFNCGLCPRHKNHTALANLVVTNRCDLSCWYCF
FYAEKMGYVYEPTLEQIRMMIRQYAKEGVVMSVQITGGEPTLRPDLPEIIKLLKEEGVRHIQLNTHGITFARLWFEKGPE
TAVEYAKKLREAGLNTVYMSFDGVTPRTNPKNHWEVPYTLEVFRRAGVTSVVLVPTVIKGINTHELGAIIKFAAKHMDVI
RGVNYQPVSLTGRMRKEEREKYRVTIPDVLKLIEEQTDGQIPADAWFPIPVAAKFAYFLEALSGELKICMANHPACGSAT
YVFVERDADGLPKRFIPITEFFDVEGFIEYMEQKTGELRAAREGRLSGFKHKLKIASIIKDLPKFVDREKLPKDLNITKL
LANVFIKRNYEALGELHYRMLFLGNMHFMDPYNYDVERVMRCNIHYLSPDGRIIPFCTYNVFTTFTATISLGSTEYQLKN
T

Sequences:

>Translated_561_residues
MLSLHSDRRSETDQRHAQILDAPARFDPKAKTVSIAGRTIRIGGPLPKLKENERFIAYTLTVCPYCYRLLPAVIFERGGK
VYIKRSCPEHGTIEELYFGDAQIYKRFMKYEEEGTGVTAYVKLEAPCPFNCGLCPRHKNHTALANLVVTNRCDLSCWYCF
FYAEKMGYVYEPTLEQIRMMIRQYAKEGVVMSVQITGGEPTLRPDLPEIIKLLKEEGVRHIQLNTHGITFARLWFEKGPE
TAVEYAKKLREAGLNTVYMSFDGVTPRTNPKNHWEVPYTLEVFRRAGVTSVVLVPTVIKGINTHELGAIIKFAAKHMDVI
RGVNYQPVSLTGRMRKEEREKYRVTIPDVLKLIEEQTDGQIPADAWFPIPVAAKFAYFLEALSGELKICMANHPACGSAT
YVFVERDADGLPKRFIPITEFFDVEGFIEYMEQKTGELRAAREGRLSGFKHKLKIASIIKDLPKFVDREKLPKDLNITKL
LANVFIKRNYEALGELHYRMLFLGNMHFMDPYNYDVERVMRCNIHYLSPDGRIIPFCTYNVFTTFTATISLGSTEYQLKN
T
>Mature_561_residues
MLSLHSDRRSETDQRHAQILDAPARFDPKAKTVSIAGRTIRIGGPLPKLKENERFIAYTLTVCPYCYRLLPAVIFERGGK
VYIKRSCPEHGTIEELYFGDAQIYKRFMKYEEEGTGVTAYVKLEAPCPFNCGLCPRHKNHTALANLVVTNRCDLSCWYCF
FYAEKMGYVYEPTLEQIRMMIRQYAKEGVVMSVQITGGEPTLRPDLPEIIKLLKEEGVRHIQLNTHGITFARLWFEKGPE
TAVEYAKKLREAGLNTVYMSFDGVTPRTNPKNHWEVPYTLEVFRRAGVTSVVLVPTVIKGINTHELGAIIKFAAKHMDVI
RGVNYQPVSLTGRMRKEEREKYRVTIPDVLKLIEEQTDGQIPADAWFPIPVAAKFAYFLEALSGELKICMANHPACGSAT
YVFVERDADGLPKRFIPITEFFDVEGFIEYMEQKTGELRAAREGRLSGFKHKLKIASIIKDLPKFVDREKLPKDLNITKL
LANVFIKRNYEALGELHYRMLFLGNMHFMDPYNYDVERVMRCNIHYLSPDGRIIPFCTYNVFTTFTATISLGSTEYQLKN
T

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116734668, Length=218, Percent_Identity=27.9816513761468, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI22027536, Length=302, Percent_Identity=26.4900662251656, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 64302; Mature: 64302

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLHSDRRSETDQRHAQILDAPARFDPKAKTVSIAGRTIRIGGPLPKLKENERFIAYTL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCEEEEEEH
TVCPYCYRLLPAVIFERGGKVYIKRSCPEHGTIEELYFGDAQIYKRFMKYEEEGTGVTAY
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEE
VKLEAPCPFNCGLCPRHKNHTALANLVVTNRCDLSCWYCFFYAEKMGYVYEPTLEQIRMM
EEEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHCCCEECCHHHHHHHH
IRQYAKEGVVMSVQITGGEPTLRPDLPEIIKLLKEEGVRHIQLNTHGITFARLWFEKGPE
HHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEEEEEEHHHCCCH
TAVEYAKKLREAGLNTVYMSFDGVTPRTNPKNHWEVPYTLEVFRRAGVTSVVLVPTVIKG
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHCC
INTHELGAIIKFAAKHMDVIRGVNYQPVSLTGRMRKEEREKYRVTIPDVLKLIEEQTDGQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCC
IPADAWFPIPVAAKFAYFLEALSGELKICMANHPACGSATYVFVERDADGLPKRFIPITE
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHH
FFDVEGFIEYMEQKTGELRAAREGRLSGFKHKLKIASIIKDLPKFVDREKLPKDLNITKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LANVFIKRNYEALGELHYRMLFLGNMHFMDPYNYDVERVMRCNIHYLSPDGRIIPFCTYN
HHHHHHHCCHHHHHHHHHHHHEECCEEECCCCCCCHHHHHCCCEEEECCCCCEEEEEEHH
VFTTFTATISLGSTEYQLKNT
HEEEEEEEEEECCCCEEECCC
>Mature Secondary Structure
MLSLHSDRRSETDQRHAQILDAPARFDPKAKTVSIAGRTIRIGGPLPKLKENERFIAYTL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCEEEEEEH
TVCPYCYRLLPAVIFERGGKVYIKRSCPEHGTIEELYFGDAQIYKRFMKYEEEGTGVTAY
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEE
VKLEAPCPFNCGLCPRHKNHTALANLVVTNRCDLSCWYCFFYAEKMGYVYEPTLEQIRMM
EEEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHCCCEECCHHHHHHHH
IRQYAKEGVVMSVQITGGEPTLRPDLPEIIKLLKEEGVRHIQLNTHGITFARLWFEKGPE
HHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCEEEEEEHHHCCCH
TAVEYAKKLREAGLNTVYMSFDGVTPRTNPKNHWEVPYTLEVFRRAGVTSVVLVPTVIKG
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHCC
INTHELGAIIKFAAKHMDVIRGVNYQPVSLTGRMRKEEREKYRVTIPDVLKLIEEQTDGQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCC
IPADAWFPIPVAAKFAYFLEALSGELKICMANHPACGSATYVFVERDADGLPKRFIPITE
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHH
FFDVEGFIEYMEQKTGELRAAREGRLSGFKHKLKIASIIKDLPKFVDREKLPKDLNITKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LANVFIKRNYEALGELHYRMLFLGNMHFMDPYNYDVERVMRCNIHYLSPDGRIIPFCTYN
HHHHHHHCCHHHHHHHHHHHHEECCEEECCCCCCCHHHHHCCCEEEECCCCCEEEEEEHH
VFTTFTATISLGSTEYQLKNT
HEEEEEEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]