Click here to switch to the map view.

The map label for this gene is mtaP [H]

Identifier: 124027941

GI number: 124027941

Start: 1090182

End: 1091000

Strand: Reverse

Name: mtaP [H]

Synonym: Hbut_1073

Alternate gene names: 124027941

Gene position: 1091000-1090182 (Counterclockwise)

Preceding gene: 124027943

Following gene: 124027940

Centisome position: 65.44

GC content: 52.38

Gene sequence:

>819_bases
TTGCCGCGTGTCCAGCCGTTTACGCGTGCATCAAAAGGTGATGTGTCCACACACGTGCTTGTAACGAGTCTTGAGGAAGT
CTACGAGGAGGCTGTTAGCAAGCTGCACGAGGTTAACGAGAGGCCTGGCAGGTATGGCTTCAAGTTAGCCACGGGGCTGA
TACACAAGGTTAGTATATCGATTGCACTTCGCCCAGTGGGGCCCTCTGCGCTAGCCATACTCGTTGAGGAGCTTGCTAGG
CTTGGCGCAAAGGTCATACTACATCTTGACACTGCCCTAGCACTATCACCATCCCTCGCCATAGGCGACGTGGTACTAGC
TACAGCAGCAATAAAGGGTGATGGTGTCTCAAAGGCTTATGCTCCAATAGAGGTGCCAGCAATACCCGACTATACCCTGC
TAAGACACATCCAGCAGTCCCTCGAGATACACAATATCAAGACGCTAACCGGTGTTGTATGGAGCATGGATATGTTCTAT
GCTAGTGAGCAAGTCTTAGAGCAGGGCGTTAAGAAGTACGGCAAGATAGCTGTCGCGCTAGACATGGATACGGCATCTCT
CTTCACTGTAGCTATGAGCAAGAAGCTCATGGCGGCATCTGTTCTCGTCATAGAGTCGAGTCTACCAAAGGGTGTTGAGA
GGGGCTCGCTACTCCTCGAGGAGGAGCGGGAGGAACTGCGAAGGAAGGTTCTAGATGCTCTGGGGCAGCTGATACAGCCG
ATACTTGAGTCACTAACACTCCACGTCGAGAAGATGAAGAGCCTCCAGTCAATGAGAGCTGGTACCGGGCACGGCAAGGG
CTTCAATAGCGGTTTCTAG

Upstream 100 bases:

>100_bases
TCGTAGGCTCTAACAGCTAATTAGCTGGTAGTCTTTTGGAGTGTTACCGCTGGCAGCGGCCCAGGGAGGGTATGAGCGGT
AGCGGAAGGGGTAGGAGCGT

Downstream 100 bases:

>100_bases
GGTGTCCCGGCATTGGAGAATATTGATGCTCTCTACGAGAGGGTAGACAAGGCGTTCTCCATACTAGAGGAGCTTGAGCG
TAGGCTAGGCATGTTCTTCC

Product: S-methyl-5-thioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPRVQPFTRASKGDVSTHVLVTSLEEVYEEAVSKLHEVNERPGRYGFKLATGLIHKVSISIALRPVGPSALAILVEELAR
LGAKVILHLDTALALSPSLAIGDVVLATAAIKGDGVSKAYAPIEVPAIPDYTLLRHIQQSLEIHNIKTLTGVVWSMDMFY
ASEQVLEQGVKKYGKIAVALDMDTASLFTVAMSKKLMAASVLVIESSLPKGVERGSLLLEEEREELRRKVLDALGQLIQP
ILESLTLHVEKMKSLQSMRAGTGHGKGFNSGF

Sequences:

>Translated_272_residues
MPRVQPFTRASKGDVSTHVLVTSLEEVYEEAVSKLHEVNERPGRYGFKLATGLIHKVSISIALRPVGPSALAILVEELAR
LGAKVILHLDTALALSPSLAIGDVVLATAAIKGDGVSKAYAPIEVPAIPDYTLLRHIQQSLEIHNIKTLTGVVWSMDMFY
ASEQVLEQGVKKYGKIAVALDMDTASLFTVAMSKKLMAASVLVIESSLPKGVERGSLLLEEEREELRRKVLDALGQLIQP
ILESLTLHVEKMKSLQSMRAGTGHGKGFNSGF
>Mature_271_residues
PRVQPFTRASKGDVSTHVLVTSLEEVYEEAVSKLHEVNERPGRYGFKLATGLIHKVSISIALRPVGPSALAILVEELARL
GAKVILHLDTALALSPSLAIGDVVLATAAIKGDGVSKAYAPIEVPAIPDYTLLRHIQQSLEIHNIKTLTGVVWSMDMFYA
SEQVLEQGVKKYGKIAVALDMDTASLFTVAMSKKLMAASVLVIESSLPKGVERGSLLLEEEREELRRKVLDALGQLIQPI
LESLTLHVEKMKSLQSMRAGTGHGKGFNSGF

Specific function: Endowed with a broad substrate specificity, being able to phosphorolytically cleave inosine, guanosine, and adenosine with a better efficiency than MTA [H]

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=147, Percent_Identity=30.6122448979592, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 29459; Mature: 29328

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVQPFTRASKGDVSTHVLVTSLEEVYEEAVSKLHEVNERPGRYGFKLATGLIHKVSIS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
IALRPVGPSALAILVEELARLGAKVILHLDTALALSPSLAIGDVVLATAAIKGDGVSKAY
EEEECCCHHHHHHHHHHHHHHHHHEEHEEHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
APIEVPAIPDYTLLRHIQQSLEIHNIKTLTGVVWSMDMFYASEQVLEQGVKKYGKIAVAL
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DMDTASLFTVAMSKKLMAASVLVIESSLPKGVERGSLLLEEEREELRRKVLDALGQLIQP
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ILESLTLHVEKMKSLQSMRAGTGHGKGFNSGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PRVQPFTRASKGDVSTHVLVTSLEEVYEEAVSKLHEVNERPGRYGFKLATGLIHKVSIS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
IALRPVGPSALAILVEELARLGAKVILHLDTALALSPSLAIGDVVLATAAIKGDGVSKAY
EEEECCCHHHHHHHHHHHHHHHHHEEHEEHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
APIEVPAIPDYTLLRHIQQSLEIHNIKTLTGVVWSMDMFYASEQVLEQGVKKYGKIAVAL
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DMDTASLFTVAMSKKLMAASVLVIESSLPKGVERGSLLLEEEREELRRKVLDALGQLIQP
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
ILESLTLHVEKMKSLQSMRAGTGHGKGFNSGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 7929153 [H]