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The map label for this gene is 124027843

Identifier: 124027843

GI number: 124027843

Start: 981588

End: 982145

Strand: Direct

Name: 124027843

Synonym: Hbut_0970

Alternate gene names: NA

Gene position: 981588-982145 (Clockwise)

Preceding gene: 124027842

Following gene: 124027846

Centisome position: 58.88

GC content: 46.95

Gene sequence:

>558_bases
TTGTCTGAGCCGCTAATGCCTGTATTGTTTGCCCCATGGAGATTCAAGTACATAAAATCGACGGTTGAAGCCGAGAAGCA
GGTCTGCATCTTCTGCGAAGCGCCACGAAAACCAGACGATGAAAGCCTCATACTATACCGTGGAAAACATAGCTACGTAA
TAATGAACCTCTACCCCTACAACACGGGTCACGTAATGGTAGTACCCTATAGGCATGTGGCAAACATAGAAGACCTATCC
GACGAAGAACTGCTAGAGATGGCAAGACTAGTCAAACTATCCATAAAAGCCATAAGGGAGGTATATCGGCCCCACGGGTT
CAACATAGGCATAAACATTGGCCGTGTAGCAGGCGCCGGTGTAGACAAGCATGTACACATACACATTGTTCCACGCTGGA
ACGGCGATACAAACTTCATGCCAATAATAGCAGGCGTAAAAGTGGTATCACAAGATGTGAAGGAATCATACAAAATGCTC
AAGCCGGCCTTTAACCGTGCAGCCCACGAGCTAGAGAGCTGGAAAGACCCTTCTCAACACCATCAAGATAAAGCCTAA

Upstream 100 bases:

>100_bases
ATCCTACTTCATAGCCCTGCTAGTCGGAGATAAACCCCTACTAGCACTAGTATCAGCCTAGACGCTTTGAACCGCAGAGC
CGAGGAGGGGTGCAGCAGAA

Downstream 100 bases:

>100_bases
TCTCACCTATATGACCCATGATCTCGTCCCTAACCCTTGAGAGGCCGCGCATGCTATGCAGCGCTTCCATACGGTTCCTA
ACAGCTGCAGCGTACCTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSEPLMPVLFAPWRFKYIKSTVEAEKQVCIFCEAPRKPDDESLILYRGKHSYVIMNLYPYNTGHVMVVPYRHVANIEDLS
DEELLEMARLVKLSIKAIREVYRPHGFNIGINIGRVAGAGVDKHVHIHIVPRWNGDTNFMPIIAGVKVVSQDVKESYKML
KPAFNRAAHELESWKDPSQHHQDKA

Sequences:

>Translated_185_residues
MSEPLMPVLFAPWRFKYIKSTVEAEKQVCIFCEAPRKPDDESLILYRGKHSYVIMNLYPYNTGHVMVVPYRHVANIEDLS
DEELLEMARLVKLSIKAIREVYRPHGFNIGINIGRVAGAGVDKHVHIHIVPRWNGDTNFMPIIAGVKVVSQDVKESYKML
KPAFNRAAHELESWKDPSQHHQDKA
>Mature_184_residues
SEPLMPVLFAPWRFKYIKSTVEAEKQVCIFCEAPRKPDDESLILYRGKHSYVIMNLYPYNTGHVMVVPYRHVANIEDLSD
EELLEMARLVKLSIKAIREVYRPHGFNIGINIGRVAGAGVDKHVHIHIVPRWNGDTNFMPIIAGVKVVSQDVKESYKMLK
PAFNRAAHELESWKDPSQHHQDKA

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320078, Length=134, Percent_Identity=28.3582089552239, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 21261; Mature: 21130

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00133 CARBOXYPEPT_ZN_2 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLMPVLFAPWRFKYIKSTVEAEKQVCIFCEAPRKPDDESLILYRGKHSYVIMNLYPY
CCCCCCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEC
NTGHVMVVPYRHVANIEDLSDEELLEMARLVKLSIKAIREVYRPHGFNIGINIGRVAGAG
CCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCC
VDKHVHIHIVPRWNGDTNFMPIIAGVKVVSQDVKESYKMLKPAFNRAAHELESWKDPSQH
CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HQDKA
CCCCC
>Mature Secondary Structure 
SEPLMPVLFAPWRFKYIKSTVEAEKQVCIFCEAPRKPDDESLILYRGKHSYVIMNLYPY
CCCCCCEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEEEEEEC
NTGHVMVVPYRHVANIEDLSDEELLEMARLVKLSIKAIREVYRPHGFNIGINIGRVAGAG
CCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCC
VDKHVHIHIVPRWNGDTNFMPIIAGVKVVSQDVKESYKMLKPAFNRAAHELESWKDPSQH
CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HQDKA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]