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The map label for this gene is tbp [H]

Identifier: 124027807

GI number: 124027807

Start: 942426

End: 943034

Strand: Direct

Name: tbp [H]

Synonym: Hbut_0934

Alternate gene names: 124027807

Gene position: 942426-943034 (Clockwise)

Preceding gene: 124027806

Following gene: 124027815

Centisome position: 56.53

GC content: 48.93

Gene sequence:

>609_bases
GTGCCGACTGGTGGCCAGAAGTTGAGCCAGATAGAGGCTAGGAGCGAGGCTGGTGAGGCTAGGCCGACGGCTAAGATAGA
GAATATAGTTGCTACGGTTTCTCTTGACCAGCAGCTCGACCTTAGGCTTATAGAACGTAGTATACTCACTGTAGAGTATA
ATCCCGAACAGTTCCCGGGTCTTGTCTATAGGCTTGACGAGCCAAAGGTTACAGCGTTGATATTCAAGTCTGGCAAAATG
GTTGTCACTGGTGCTAAGAGCACAAAGGACCTCATAGAGGCTGTTAAGAAGATTGTCAGGAACCTCAAGAAGCATGGAAT
ACCAATCTATGGTAGGCCCAAGGTACAGATACAGAATATCGTAGCCTCGGCTAACCTCAACGTCTGTGTTGACCTCGAGA
GGGCTGCACTTACGCTTGAGAACAGTATGTACGAGCCTGAGCAGTTCCCAGGCCTCATACATAGAATGGATGAGCCGAGG
GTAGTGCTCCTAATCTTCAGCTCGGGCAAGATGGTTATCACGGGTGCCAAGAGAGAGGAAGAAGTCTATGAGGCTGTAAA
CAAGATATACGAGAAGCTCAAGAAGCTAAGAGCGATAAGGCCTTGCTAG

Upstream 100 bases:

>100_bases
GGTCCTAGACTGCCCGCCTCTCCATCCCCCAGAAGCTACAGTACGTACGGGTAAGGCTTTAAATCGGCTTTTTATAGGGG
TTATAAGGGGGTTTGCTGGC

Downstream 100 bases:

>100_bases
CCAGTTTTTATCCTCAGCCCACGCTTCAGAGCTGCGAGCACTAGCTCTTTTACAGCATTCCGCGACCTAGACCTCACTAT
AACAATGCTGCCAATATCTT

Product: transcription factor

Products: NA

Alternate protein names: Box A-binding protein; BAP; TATA sequence-binding protein; TBP; TATA-box factor [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPTGGQKLSQIEARSEAGEARPTAKIENIVATVSLDQQLDLRLIERSILTVEYNPEQFPGLVYRLDEPKVTALIFKSGKM
VVTGAKSTKDLIEAVKKIVRNLKKHGIPIYGRPKVQIQNIVASANLNVCVDLERAALTLENSMYEPEQFPGLIHRMDEPR
VVLLIFSSGKMVITGAKREEEVYEAVNKIYEKLKKLRAIRPC

Sequences:

>Translated_202_residues
MPTGGQKLSQIEARSEAGEARPTAKIENIVATVSLDQQLDLRLIERSILTVEYNPEQFPGLVYRLDEPKVTALIFKSGKM
VVTGAKSTKDLIEAVKKIVRNLKKHGIPIYGRPKVQIQNIVASANLNVCVDLERAALTLENSMYEPEQFPGLIHRMDEPR
VVLLIFSSGKMVITGAKREEEVYEAVNKIYEKLKKLRAIRPC
>Mature_201_residues
PTGGQKLSQIEARSEAGEARPTAKIENIVATVSLDQQLDLRLIERSILTVEYNPEQFPGLVYRLDEPKVTALIFKSGKMV
VTGAKSTKDLIEAVKKIVRNLKKHGIPIYGRPKVQIQNIVASANLNVCVDLERAALTLENSMYEPEQFPGLIHRMDEPRV
VLLIFSSGKMVITGAKREEEVYEAVNKIYEKLKKLRAIRPC

Specific function: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation [H]

COG id: COG2101

COG function: function code K; TATA-box binding protein (TBP), component of TFIID and TFIIIB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TBP family [H]

Homologues:

Organism=Homo sapiens, GI4507379, Length=174, Percent_Identity=48.2758620689655, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI285026520, Length=174, Percent_Identity=48.2758620689655, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI39930602, Length=174, Percent_Identity=47.7011494252874, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI4759234, Length=166, Percent_Identity=29.5180722891566, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555358, Length=177, Percent_Identity=46.3276836158192, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193202769, Length=184, Percent_Identity=27.7173913043478, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17509361, Length=184, Percent_Identity=27.7173913043478, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320996, Length=173, Percent_Identity=48.5549132947977, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17647997, Length=183, Percent_Identity=48.0874316939891, Blast_Score=156, Evalue=8e-39,
Organism=Drosophila melanogaster, GI17136834, Length=197, Percent_Identity=38.0710659898477, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281360601, Length=179, Percent_Identity=31.2849162011173, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161077628, Length=179, Percent_Identity=31.2849162011173, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012295
- InterPro:   IPR000814
- InterPro:   IPR012294 [H]

Pfam domain/function: PF00352 TBP [H]

EC number: NA

Molecular weight: Translated: 22656; Mature: 22525

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00351 TFIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTGGQKLSQIEARSEAGEARPTAKIENIVATVSLDQQLDLRLIERSILTVEYNPEQFPG
CCCCCHHHHHHHHHHHCCCCCCCHHHHHEEEEEECCCHHHHHHHHHEEEEEEECCCCCCC
LVYRLDEPKVTALIFKSGKMVVTGAKSTKDLIEAVKKIVRNLKKHGIPIYGRPKVQIQNI
EEEEECCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
VASANLNVCVDLERAALTLENSMYEPEQFPGLIHRMDEPRVVLLIFSSGKMVITGAKREE
HHHCCCEEEEEEHHHHEEHHCCCCCCHHCCHHHHCCCCCCEEEEEECCCCEEEECCCCHH
EVYEAVNKIYEKLKKLRAIRPC
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTGGQKLSQIEARSEAGEARPTAKIENIVATVSLDQQLDLRLIERSILTVEYNPEQFPG
CCCCHHHHHHHHHHHCCCCCCCHHHHHEEEEEECCCHHHHHHHHHEEEEEEECCCCCCC
LVYRLDEPKVTALIFKSGKMVVTGAKSTKDLIEAVKKIVRNLKKHGIPIYGRPKVQIQNI
EEEEECCCCEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
VASANLNVCVDLERAALTLENSMYEPEQFPGLIHRMDEPRVVLLIFSSGKMVITGAKREE
HHHCCCEEEEEEHHHHEEHHCCCCCCHHCCHHHHCCCCCCEEEEEECCCCEEEECCCCHH
EVYEAVNKIYEKLKKLRAIRPC
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA