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The map label for this gene is mtaP [H]

Identifier: 124027795

GI number: 124027795

Start: 927841

End: 928578

Strand: Direct

Name: mtaP [H]

Synonym: Hbut_0922

Alternate gene names: 124027795

Gene position: 927841-928578 (Clockwise)

Preceding gene: 124027788

Following gene: 124027796

Centisome position: 55.65

GC content: 52.98

Gene sequence:

>738_bases
ATGAAGCCCCAGCACATAAGAGTGAGCCCGGACCGTGTTGCAGCTAAAGTGGTTGTAGTGGGTGATCCTGCCAGGGCTCG
GTTCATAGCCGAGCACCTTCTCGAGGATGCCGAGCTGGTTAACGAGGAGAGGTGCTTCCACCTCTATACTGGGTTCTACC
GTGGGGAGAGAATTAGCGTAGCCGTGCATGGTGTAGGTGCAGCTTCCTCAGCTATAGTCTTTGAGGAGCTTAGAATGCTC
GGTGCAAAGGTCATGGTCCGGCTTGGTACTGCTGGTGCGCTAATGCCAGAGCTTGATATAGGTGACATGGTTGTCGCTAC
TGGTGCAGCCTACGTTCACGGAGGAACCATAGGCTCCTACGTCCCCGATGCTTGTATGGCCACAGCACCAAACCCGTTGC
TTCTCACAAAGCTATATGATTATGCTAAGAGGATACACGGTCGTGTAGTCTTAGGTCCCGTGTTTAGCAGCGATGCCTTC
TATGCTGAGGATCCGGAGTTCGCCAAGAAATGGTTCTCAAGAGGCATAGTGGCTGTTGAAATGGAGGTTGCAACTCTCTA
CGCACTGGCGGCGCTGAGGAGGTTCGATGCTGCAGCTGCACTCGTCATATCTGATAACCTCGTCGTACCAGGTAAGGAGG
AGTTACGGCACCACCGCGAGCTTGAACCCTACGTGGAAAAGGCTGCCAAAGCAGTGCTCGAGGCGCTTAGAGACTATAAT
CCCAGTAATATAAGCTAA

Upstream 100 bases:

>100_bases
CTGCATATCCCTCTCACTTAGGGCTACGCAACAGGGCGCTCATCATGGCCCGTAGACGCTAAAGCTGCAGAGTCCCCCTC
TTCTCCTCTCTGGTGAGTGT

Downstream 100 bases:

>100_bases
TGGTTACCTGGAGCCTATGAGGAGGCCTTGGACGTGCTGAAGGGTGAAGAGAGCCGTGGCTCCCGAGGCTCTAGCCGAGG
ATGTGCGTAGAATCATGAGA

Product: S-methyl-5-thioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKPQHIRVSPDRVAAKVVVVGDPARARFIAEHLLEDAELVNEERCFHLYTGFYRGERISVAVHGVGAASSAIVFEELRML
GAKVMVRLGTAGALMPELDIGDMVVATGAAYVHGGTIGSYVPDACMATAPNPLLLTKLYDYAKRIHGRVVLGPVFSSDAF
YAEDPEFAKKWFSRGIVAVEMEVATLYALAALRRFDAAAALVISDNLVVPGKEELRHHRELEPYVEKAAKAVLEALRDYN
PSNIS

Sequences:

>Translated_245_residues
MKPQHIRVSPDRVAAKVVVVGDPARARFIAEHLLEDAELVNEERCFHLYTGFYRGERISVAVHGVGAASSAIVFEELRML
GAKVMVRLGTAGALMPELDIGDMVVATGAAYVHGGTIGSYVPDACMATAPNPLLLTKLYDYAKRIHGRVVLGPVFSSDAF
YAEDPEFAKKWFSRGIVAVEMEVATLYALAALRRFDAAAALVISDNLVVPGKEELRHHRELEPYVEKAAKAVLEALRDYN
PSNIS
>Mature_245_residues
MKPQHIRVSPDRVAAKVVVVGDPARARFIAEHLLEDAELVNEERCFHLYTGFYRGERISVAVHGVGAASSAIVFEELRML
GAKVMVRLGTAGALMPELDIGDMVVATGAAYVHGGTIGSYVPDACMATAPNPLLLTKLYDYAKRIHGRVVLGPVFSSDAF
YAEDPEFAKKWFSRGIVAVEMEVATLYALAALRRFDAAAALVISDNLVVPGKEELRHHRELEPYVEKAAKAVLEALRDYN
PSNIS

Specific function: Endowed with a broad substrate specificity, being able to phosphorolytically cleave inosine, guanosine, and adenosine with a better efficiency than MTA [H]

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=208, Percent_Identity=34.1346153846154, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790265, Length=238, Percent_Identity=27.3109243697479, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 26722; Mature: 26722

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPQHIRVSPDRVAAKVVVVGDPARARFIAEHLLEDAELVNEERCFHLYTGFYRGERISV
CCCCCEEECHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEHHHEECCCEEEE
AVHGVGAASSAIVFEELRMLGAKVMVRLGTAGALMPELDIGDMVVATGAAYVHGGTIGSY
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCC
VPDACMATAPNPLLLTKLYDYAKRIHGRVVLGPVFSSDAFYAEDPEFAKKWFSRGIVAVE
CCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEE
MEVATLYALAALRRFDAAAALVISDNLVVPGKEELRHHRELEPYVEKAAKAVLEALRDYN
HHHHHHHHHHHHHHHHHHEEEEEECCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PSNIS
CCCCC
>Mature Secondary Structure
MKPQHIRVSPDRVAAKVVVVGDPARARFIAEHLLEDAELVNEERCFHLYTGFYRGERISV
CCCCCEEECHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHEEEHHHEECCCEEEE
AVHGVGAASSAIVFEELRMLGAKVMVRLGTAGALMPELDIGDMVVATGAAYVHGGTIGSY
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCC
VPDACMATAPNPLLLTKLYDYAKRIHGRVVLGPVFSSDAFYAEDPEFAKKWFSRGIVAVE
CCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHCCEEEEE
MEVATLYALAALRRFDAAAALVISDNLVVPGKEELRHHRELEPYVEKAAKAVLEALRDYN
HHHHHHHHHHHHHHHHHHEEEEEECCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
PSNIS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 7929153 [H]