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The map label for this gene is 124027772

Identifier: 124027772

GI number: 124027772

Start: 901599

End: 902162

Strand: Direct

Name: 124027772

Synonym: Hbut_0898

Alternate gene names: NA

Gene position: 901599-902162 (Clockwise)

Preceding gene: 124027771

Following gene: 124027773

Centisome position: 54.08

GC content: 53.55

Gene sequence:

>564_bases
TTGCACAGCTACGTAGTCGTAACTGGCCGCCCCGGCGTTGGTAAAACTACGCTCTTCTGGAAGGTTGTACGGAAACTCAT
GGATGAAGGTGTGGTTGTCAAAGGATTCTATTGCCCAGAGGTTCGTGGCCAGCAAGGCTACAGGATTGGCTTCAAGATAG
TATTGCTGGATGGTAGTGGCGAAGCCTGGCTAGCTAGGAGAGAGGGTTGCAATGGGCCAAGGGTGGGGAGATATTACACC
TGCCCTGAAGCCGAGACCATAGCATCCAGGGTGCTGGGAGAACTAGGCAAGGCAGACCTCATAGCTATAGACGAGATTGG
CCCCATGGAGCTAAGGCTTGCCGGCGTACGCAGAACAATATATCGCGTCCTTGACAGCGGCAAACCGGGCCTCTTTGTGG
TTCACGAGAGGCTCTCGGATCCCTACATACTAGCTAGGCTGAAGCCCAGCGGAGTATGGTTCCACGTAACCATAGAGAAT
AGGGATGTGCTGCCCGAGAAGGTGTATGAAGCGGTTAAGCAAGCAGTTGCACGAAGCAAGGGCGTAGGAGAGCTTAGTCT
ATAG

Upstream 100 bases:

>100_bases
CCAGCGACTACGCAAAACTACTGGTGGAGAGTGGCTCTAAAATTGGTTCCCAACACCTTTCCTTGGATGGCTCACCGAAT
AGTGCTGGGTGCAACTGGTC

Downstream 100 bases:

>100_bases
GCCCCTATGGCTCAGCTAACATCTAGAAACTTGGAGGGCGGGATGCCCGCGCGTTCCAGCGCTGATGCCTAACCCGGGGG
CTGTGATGTAGTCTACACCT

Product: hypothetical protein

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSGEAWLARREGCNGPRVGRYYT
CPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTIYRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIEN
RDVLPEKVYEAVKQAVARSKGVGELSL

Sequences:

>Translated_187_residues
MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSGEAWLARREGCNGPRVGRYYT
CPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTIYRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIEN
RDVLPEKVYEAVKQAVARSKGVGELSL
>Mature_187_residues
MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSGEAWLARREGCNGPRVGRYYT
CPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTIYRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIEN
RDVLPEKVYEAVKQAVARSKGVGELSL

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family

Homologues:

Organism=Drosophila melanogaster, GI85726488, Length=181, Percent_Identity=32.0441988950276, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPTH_HYPBU (A2BL86)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001013092.1
- ProteinModelPortal:   A2BL86
- SMR:   A2BL86
- STRING:   A2BL86
- GeneID:   4782722
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_0898
- eggNOG:   arNOG12990
- HOGENOM:   HBG574935
- OMA:   MEFKSNE
- BioCyc:   HBUT415426:HBUT_0898-MONOMER
- HAMAP:   MF_00796
- InterPro:   IPR004948

Pfam domain/function: PF03266 DUF265

EC number: =3.6.1.15

Molecular weight: Translated: 20774; Mature: 20774

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSG
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEEEECCC
EAWLARREGCNGPRVGRYYTCPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTI
CEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHH
YRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIENRDVLPEKVYEAVKQAVARSK
HHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GVGELSL
CCCCCCC
>Mature Secondary Structure
MHSYVVVTGRPGVGKTTLFWKVVRKLMDEGVVVKGFYCPEVRGQQGYRIGFKIVLLDGSG
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEEEECCC
EAWLARREGCNGPRVGRYYTCPEAETIASRVLGELGKADLIAIDEIGPMELRLAGVRRTI
CEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHH
YRVLDSGKPGLFVVHERLSDPYILARLKPSGVWFHVTIENRDVLPEKVYEAVKQAVARSK
HHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GVGELSL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA