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The map label for this gene is nadA [H]

Identifier: 124027561

GI number: 124027561

Start: 661626

End: 662573

Strand: Reverse

Name: nadA [H]

Synonym: Hbut_0680

Alternate gene names: 124027561

Gene position: 662573-661626 (Counterclockwise)

Preceding gene: 124027562

Following gene: 124027560

Centisome position: 39.74

GC content: 56.75

Gene sequence:

>948_bases
TTGGGGCTGAATAGCCCCTTGACTGGCAACGGTTTGGAGGCTATTCTGGAGCGTATCCGGGAGCTGAAGGAGAAGAGGAG
AGCGGTTATATTAGCCCATAATTACCAGCTACCCGAGATCCAGGATATAGCGGATTTTGTCGGGGATAGTCTGGAGCTTG
CCCGCAAAGCTATGGAGGTTGACGCCGACGTCATAGTTATGGCAGCGGTTAACTTCATGGCCGAGGTGGCTGCGATACTC
AACCCGGACAAGATAGTACTGCATCCAGACCCCCGTGCCACGTGCCCCTTAGCCAACCACGCGAGGCTTGAGCTGCTACG
CCGCTATCGTGAGAAGTACCCCGGTGCACCTCTCGTCATCTACATCAACTCCTATGCTGTCGCAAAGGCCTATGCAGACT
ATATCGTCACAAGCGCCTCGGCGGTGAAGCTTGTTGGGAAGCTGGGAGAGGATACTATACTCTTCGCGCCCGACCGCAAC
CTTGCAGACCACGTGGCTATGGCTACCGGGAAAAACGTCGTAGCTGTCCCTGCTGGTGGCATCTGCCCAGTCCACGAGTT
CCTCCTAGACGAGTACTATGTCAGGAAGGTGCGTGAACAGTATCCCCGCGGCTACCTGATGGTGCACCCGGAGACCCCCA
GGCCCGTCCGACTCATGGCGGACTACGTTGGGAGTACTAGCCAGATGCTCCGCAGGATAGGCGAGGTCGAAGCCGAGGTA
TACATTATCGGTACCGAGGAGGGTCTAGTCCACCGCGCCAGGAGGCTCTACCCCGACAAGAAGATAGTACCCGCCAACCC
CAGAGCCGTCTGCATAAACATGAAGAAGATTACGCCGCTAAAGATACTCTACTCCCTAGAGACGCTGAAGCCCAGGGTAG
TCGTACCAGAGCCAATTGCGAGGCGCGTCCGCGAAATCCTTGAGCGCTCCCTGGAGATGGTAAGGTAG

Upstream 100 bases:

>100_bases
TTGTCGCGGTGGTCTATTTTCCTCGTGTGAATGTTTGGTGTAAATGTATGCACACTCTTTGTAGCGAAGGATATATCGGT
GGATATGGCCTTGTTCTAGC

Downstream 100 bases:

>100_bases
CCTTGTGGGTGGCTGGGTTGTTCCTCGACCCCTACACCGTTGCGGAAAAGCTGCTTGAATGGGTTGAGGAGGACGCGCCC
TTCGGCGACCTGACTACGGG

Product: quinolinate synthetase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGLNSPLTGNGLEAILERIRELKEKRRAVILAHNYQLPEIQDIADFVGDSLELARKAMEVDADVIVMAAVNFMAEVAAIL
NPDKIVLHPDPRATCPLANHARLELLRRYREKYPGAPLVIYINSYAVAKAYADYIVTSASAVKLVGKLGEDTILFAPDRN
LADHVAMATGKNVVAVPAGGICPVHEFLLDEYYVRKVREQYPRGYLMVHPETPRPVRLMADYVGSTSQMLRRIGEVEAEV
YIIGTEEGLVHRARRLYPDKKIVPANPRAVCINMKKITPLKILYSLETLKPRVVVPEPIARRVREILERSLEMVR

Sequences:

>Translated_315_residues
MGLNSPLTGNGLEAILERIRELKEKRRAVILAHNYQLPEIQDIADFVGDSLELARKAMEVDADVIVMAAVNFMAEVAAIL
NPDKIVLHPDPRATCPLANHARLELLRRYREKYPGAPLVIYINSYAVAKAYADYIVTSASAVKLVGKLGEDTILFAPDRN
LADHVAMATGKNVVAVPAGGICPVHEFLLDEYYVRKVREQYPRGYLMVHPETPRPVRLMADYVGSTSQMLRRIGEVEAEV
YIIGTEEGLVHRARRLYPDKKIVPANPRAVCINMKKITPLKILYSLETLKPRVVVPEPIARRVREILERSLEMVR
>Mature_314_residues
GLNSPLTGNGLEAILERIRELKEKRRAVILAHNYQLPEIQDIADFVGDSLELARKAMEVDADVIVMAAVNFMAEVAAILN
PDKIVLHPDPRATCPLANHARLELLRRYREKYPGAPLVIYINSYAVAKAYADYIVTSASAVKLVGKLGEDTILFAPDRNL
ADHVAMATGKNVVAVPAGGICPVHEFLLDEYYVRKVREQYPRGYLMVHPETPRPVRLMADYVGSTSQMLRRIGEVEAEVY
IIGTEEGLVHRARRLYPDKKIVPANPRAVCINMKKITPLKILYSLETLKPRVVVPEPIARRVREILERSLEMVR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=255, Percent_Identity=35.6862745098039, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35366; Mature: 35235

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNSPLTGNGLEAILERIRELKEKRRAVILAHNYQLPEIQDIADFVGDSLELARKAMEV
CCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHC
DADVIVMAAVNFMAEVAAILNPDKIVLHPDPRATCPLANHARLELLRRYREKYPGAPLVI
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
YINSYAVAKAYADYIVTSASAVKLVGKLGEDTILFAPDRNLADHVAMATGKNVVAVPAGG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCC
ICPVHEFLLDEYYVRKVREQYPRGYLMVHPETPRPVRLMADYVGSTSQMLRRIGEVEAEV
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEE
YIIGTEEGLVHRARRLYPDKKIVPANPRAVCINMKKITPLKILYSLETLKPRVVVPEPIA
EEEECCHHHHHHHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCEECCCHHH
RRVREILERSLEMVR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLNSPLTGNGLEAILERIRELKEKRRAVILAHNYQLPEIQDIADFVGDSLELARKAMEV
CCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHC
DADVIVMAAVNFMAEVAAILNPDKIVLHPDPRATCPLANHARLELLRRYREKYPGAPLVI
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
YINSYAVAKAYADYIVTSASAVKLVGKLGEDTILFAPDRNLADHVAMATGKNVVAVPAGG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCC
ICPVHEFLLDEYYVRKVREQYPRGYLMVHPETPRPVRLMADYVGSTSQMLRRIGEVEAEV
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEE
YIIGTEEGLVHRARRLYPDKKIVPANPRAVCINMKKITPLKILYSLETLKPRVVVPEPIA
EEEECCHHHHHHHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCEECCCHHH
RRVREILERSLEMVR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]