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The map label for this gene is soxB [H]

Identifier: 124027507

GI number: 124027507

Start: 600440

End: 601630

Strand: Reverse

Name: soxB [H]

Synonym: Hbut_0625

Alternate gene names: 124027507

Gene position: 601630-600440 (Counterclockwise)

Preceding gene: 124027508

Following gene: 124027506

Centisome position: 36.09

GC content: 58.19

Gene sequence:

>1191_bases
GTGCCGCTCCCCCAGCGCATAGTGACGGAGAGGCCACCACGGGAGGCAGATATAGCTATTATTGGGGGTGGCGTTGCAGG
CTTAGCCCTAGCCTACTACCTTGCAAGAATAGGGTATCCTGGCAGGGTTGTGGTTCTCGAGCAGCACAGCATTTTCTATG
GCTCCACGACAAGAAACGCTGGGAGGTTCCGTGTACACTTCTTCTCCCGGGAGAACACTGTATTCGCCAGGGAGTCCGCC
AGGAGGATACTCGAAATACCCAGGGTAACGGGTGTAAACCCTGTTATAGCTCGGCGGGGCTACCTCTGGCTCGTACAACG
TGAGGATAGCTTGGAGAAGCTCCGTAAAGTCAATAGGGAGATATGGGAGCCTCTCGGCGTGCCAGTAAGGTTTCTCGAAA
TTGGGGAGGTTGCTGAGCGGCACCCCTACATAAACCTTGAAGGCTTCGTGGCTGGAGTCTTTGGTCCCCAGAATGGGAGC
TTACACCACGACTACATGTCCATGGCTCTTGCCTCCTATGCTGCAAGACACGGCGTAGCCATTGTTGAGGGTGCTAGGGT
TGAGCGGATACTCGTTAACGGCAGCAGAGTCGCTGGGGTCCATGTAGAGGGCTTCGGGAGCATCCGGGCTGGAACAGTGG
TTGTTGCTGCTGGGTCTTGGAGCCGCCGTCTCCTCCAGACAGCTGGCGTTGATCTCCCCCTGGATCCTGTCCGTAAAAGC
CTCCTGGTGACGGAGCCCTACCGCTACACCATAGGCCCCCTAGTGATAGTATTCGAGGAGGGCTCATACATTGGGCAGAC
GCTGAAGGGCGAGGTAATAGCAACCGGGAAGACCAGGGATCCGAAGACGCTAGACTTTGGCGGTGTATCCCTCGAATGGC
TCCGAGCCACTGCTCGGCTGCTAGCGAGGCTTCTGAAGGGTGGTTCGTGCCTCCGCATCCTCCGGGCTTGGAGCGGCACC
TATAACGTAACCCCCGACCACAGCCACGTGCTTGGCAGGGGCTCTGAGTGGCCGGAGGGCCTCTACGTTGACACGGGCTA
CAGCGGTCACGGCCTAATGATGGCACCCTATGCCGGCGAGCTTCTCGCAAAACTCATCGCCGAAGACAAGGAGCATCCAC
ACATGAAGCCCTACAACCCGGACAGGTTTAGGGAGGGCCGCCTCATACCGGAGGGCCTAGTCCTAGGCTAG

Upstream 100 bases:

>100_bases
ACCGGGTACCCGTCAACAGTATCGGTGTTTTCCGCGCAAGGCCCCCACTATCCCTGCCCCAGGTATCACTACTCGCATAG
CCCGAGATGGGTGGACTATT

Downstream 100 bases:

>100_bases
GAGGGTGGAATGTGTGGCCGGGCTCGACTGCATCCTCTCGAAGCTCGAGCTGCCATCCAATAGCCTCTCCCCAGAATGGG
GAGGCGGTGGGGTCTACGGC

Product: sarcosine dehydrogenase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPLPQRIVTERPPREADIAIIGGGVAGLALAYYLARIGYPGRVVVLEQHSIFYGSTTRNAGRFRVHFFSRENTVFARESA
RRILEIPRVTGVNPVIARRGYLWLVQREDSLEKLRKVNREIWEPLGVPVRFLEIGEVAERHPYINLEGFVAGVFGPQNGS
LHHDYMSMALASYAARHGVAIVEGARVERILVNGSRVAGVHVEGFGSIRAGTVVVAAGSWSRRLLQTAGVDLPLDPVRKS
LLVTEPYRYTIGPLVIVFEEGSYIGQTLKGEVIATGKTRDPKTLDFGGVSLEWLRATARLLARLLKGGSCLRILRAWSGT
YNVTPDHSHVLGRGSEWPEGLYVDTGYSGHGLMMAPYAGELLAKLIAEDKEHPHMKPYNPDRFREGRLIPEGLVLG

Sequences:

>Translated_396_residues
MPLPQRIVTERPPREADIAIIGGGVAGLALAYYLARIGYPGRVVVLEQHSIFYGSTTRNAGRFRVHFFSRENTVFARESA
RRILEIPRVTGVNPVIARRGYLWLVQREDSLEKLRKVNREIWEPLGVPVRFLEIGEVAERHPYINLEGFVAGVFGPQNGS
LHHDYMSMALASYAARHGVAIVEGARVERILVNGSRVAGVHVEGFGSIRAGTVVVAAGSWSRRLLQTAGVDLPLDPVRKS
LLVTEPYRYTIGPLVIVFEEGSYIGQTLKGEVIATGKTRDPKTLDFGGVSLEWLRATARLLARLLKGGSCLRILRAWSGT
YNVTPDHSHVLGRGSEWPEGLYVDTGYSGHGLMMAPYAGELLAKLIAEDKEHPHMKPYNPDRFREGRLIPEGLVLG
>Mature_395_residues
PLPQRIVTERPPREADIAIIGGGVAGLALAYYLARIGYPGRVVVLEQHSIFYGSTTRNAGRFRVHFFSRENTVFARESAR
RILEIPRVTGVNPVIARRGYLWLVQREDSLEKLRKVNREIWEPLGVPVRFLEIGEVAERHPYINLEGFVAGVFGPQNGSL
HHDYMSMALASYAARHGVAIVEGARVERILVNGSRVAGVHVEGFGSIRAGTVVVAAGSWSRRLLQTAGVDLPLDPVRKSL
LVTEPYRYTIGPLVIVFEEGSYIGQTLKGEVIATGKTRDPKTLDFGGVSLEWLRATARLLARLLKGGSCLRILRAWSGTY
NVTPDHSHVLGRGSEWPEGLYVDTGYSGHGLMMAPYAGELLAKLIAEDKEHPHMKPYNPDRFREGRLIPEGLVLG

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=368, Percent_Identity=25.8152173913043, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI197927446, Length=396, Percent_Identity=26.010101010101, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI21361378, Length=396, Percent_Identity=26.010101010101, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI24797151, Length=245, Percent_Identity=27.7551020408163, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI8923708, Length=439, Percent_Identity=25.2847380410023, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787438, Length=271, Percent_Identity=26.1992619926199, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130091, Length=392, Percent_Identity=25.2551020408163, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571104, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 43773; Mature: 43642

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPQRIVTERPPREADIAIIGGGVAGLALAYYLARIGYPGRVVVLEQHSIFYGSTTRNA
CCCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCC
GRFRVHFFSRENTVFARESARRILEIPRVTGVNPVIARRGYLWLVQREDSLEKLRKVNRE
CEEEEEEEECCCEEEEHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHH
IWEPLGVPVRFLEIGEVAERHPYINLEGFVAGVFGPQNGSLHHDYMSMALASYAARHGVA
HHHHCCCCEEEEEHHHHHHHCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEE
IVEGARVERILVNGSRVAGVHVEGFGSIRAGTVVVAAGSWSRRLLQTAGVDLPLDPVRKS
EEECCEEEEEEECCCEEEEEEEECCCCEECCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
LLVTEPYRYTIGPLVIVFEEGSYIGQTLKGEVIATGKTRDPKTLDFGGVSLEWLRATARL
EEEECCCEEECCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHH
LARLLKGGSCLRILRAWSGTYNVTPDHSHVLGRGSEWPEGLYVDTGYSGHGLMMAPYAGE
HHHHHCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCEEEECCCCCCCEEECCCHHH
LLAKLIAEDKEHPHMKPYNPDRFREGRLIPEGLVLG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLPQRIVTERPPREADIAIIGGGVAGLALAYYLARIGYPGRVVVLEQHSIFYGSTTRNA
CCCCCHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCCCCC
GRFRVHFFSRENTVFARESARRILEIPRVTGVNPVIARRGYLWLVQREDSLEKLRKVNRE
CEEEEEEEECCCEEEEHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHH
IWEPLGVPVRFLEIGEVAERHPYINLEGFVAGVFGPQNGSLHHDYMSMALASYAARHGVA
HHHHCCCCEEEEEHHHHHHHCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEE
IVEGARVERILVNGSRVAGVHVEGFGSIRAGTVVVAAGSWSRRLLQTAGVDLPLDPVRKS
EEECCEEEEEEECCCEEEEEEEECCCCEECCEEEEEECCHHHHHHHHCCCCCCHHHHHHH
LLVTEPYRYTIGPLVIVFEEGSYIGQTLKGEVIATGKTRDPKTLDFGGVSLEWLRATARL
EEEECCCEEECCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHH
LARLLKGGSCLRILRAWSGTYNVTPDHSHVLGRGSEWPEGLYVDTGYSGHGLMMAPYAGE
HHHHHCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCEEEECCCCCCCEEECCCHHH
LLAKLIAEDKEHPHMKPYNPDRFREGRLIPEGLVLG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]