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The map label for this gene is dppA [H]

Identifier: 124027493

GI number: 124027493

Start: 580945

End: 583164

Strand: Direct

Name: dppA [H]

Synonym: Hbut_0609

Alternate gene names: 124027493

Gene position: 580945-583164 (Clockwise)

Preceding gene: 124027486

Following gene: 124027495

Centisome position: 34.85

GC content: 50.81

Gene sequence:

>2220_bases
GTGGGAGTTGTGGCGAGTCGTGCGGCTTTAATAGCTGGTATTGTTGTGCTTGTTGTTATTGTTGCTGGTATTGCGGTCTA
CTTTGCCTCCAAGCCTGAGGAGAAGCCTGCAGCACCAACCGAACAGCCAACAGAACAACCAACAACAACACCAACAGAAG
AAAAGCCTGCTGAAGAGCAACCGGTACAGGCGGCAAAGCCTCAGCTTCCACCCGAGGTCAAGGTTATAGAGGTTAGCAAG
GCTGTAATCGCTGTTGCACCAAAGGATGTAGCTGTCGAGGACATAGTTAACGCGATTGATACTAAGGGCAAGAAGCTGAT
AATTGTCCGCTACGAGGTTGATGAGGAGAACACTAAGCCGGTAGAAGAAAGTGTAGGCTTCTCCGACATAAACCCAGCAT
TCTATAGGAACACAACGATAGACGCACTAATCATAGCTGCGAGAAAGGAGACCAACCCCGAGATACGTGAAATGCTCTAT
GAAGCTGTCTACAAGCTGAGCAACTACGAGGTACCAATACTCTGGCTTGGCCAGTATATGCTTGTGCGTAGTCAGTGGAG
CTGGGTGCACGGCCGCTACTATCACCCAACACTAGCTGAGCGCTACGACTTGCTATGGGAGGATCCAGCTGCGCCTGTGA
AGAACCTGGAGTTTGGTGGCTACAAGAATGACCCCTCAACATACGTGATAGCAACTATAGGCTGGCCTGACACCTTCGAC
CCAGCAGCAGACTATGAGACCTTCGGCTGGGCGATATTCCACAACATTGGTGACACTCTAGTAACCTACTGGAAGGATGA
TACTAAGGAGGTTATACCAGACCTAGCTGTTGCATGGGTACACGATAAGGAAGGTACAACCTGGTACTTCGTGATACGTG
GCGGTGTAAAGGCCTACGATCCATGGCACAACAAGGTCTACGATATAAGTGCTGTAGACGTGTTATTCACAATATGGCGT
GTAGCGAGGCTAGGCCTAGACCCGAGCTGGATGGTTACAGAGTTCATTGACGTAAACAACTCCAAGGTGCTAACTGAGGA
GGAGTTCGACCAGATACTAGCCCAGGGCGGCCTCTATGCAGACTACAAGGGCCAGACGATAGAGCCTAAGAGCTTGAAGG
AGCTGCTAGAATTCTTCGGCTACGATGGTGAGACTGCTGGTGTTGTAATGCTCAAGCTATACATGCCGTACAGCCCGATA
CTCAGCATACTCAGCGACCCATTCCTAATAGTCATCCCGATGAAGTACTTGTTTGACAATGTCGACGAGTTGAAGGGCAA
ATATGAGGAGGCCCTGGAGGCAAGCCAGTACGGCAAGAACCCGGCAGCGTGGGCCAACTATATAGGCACGGGTGAGCAGG
AGCCGACGCACCTCTACCTCCACAAATACCCCATTGGCACCGGGCCATACTATGTTGCCGAGTACAAGGAGGATAGCTAC
ATAGTGCTAAAGTACAACCCATACTACTGGAACAAGAGCCTATGGTACATGGAGCCCTATGGTAAGGATGGTGTGCCAAG
CCACCAGACAGTAATCTACCTTATAGCCAACGACCACGTAACAAGGCTGCAGATCTACAAGGCTGGCCAGGCCGACACAG
CAGTTGTGCCGCTCGATAGGCTTGACGAAGTTAGAGACTACAAGCTGCAGGACAACCCACAGTTCAAGATAGAGGTGGAG
ACTGGCGGACTAGAGCCAGCGATAGTCTACATAGTGCTCAACGCTAACAAGGAGCCATTCAACAATAGGCTTGTAAGGCA
GGCGTTAATGTATGCTATACCATTCGACCAGATCAAGGAGGTGGTATACTCCGGGTTCCTTGAGAGGCTATATGGTGTCA
TACCTGCAGGCTTCCCAGGCCACAACGATGACATAGTGATAAAGTACACGTTCGACCTAGACAAGGCTATGGAGCTGATA
CAGAAGAGCGGTATAGACCCAACCAAGTATAACATCGAGATCTGGTACAACGAGGGTAACGCACAGCGCGAACAGATAGC
CACCCTGCTACAGCAGACATGGGGCCAGCTAGGCTTCAAGGTTGGCGTAAAGGCGCTCAACTGGCCAACGCTACTATCAA
AGACCGAGAAGGGCGACTTCGACGTATACATCATCGGCTGGGCGCCAGACTACCTAGACCCAGACAACTATGCAGGCCCA
CTATTCTACGGTGGTACCAGGTTCAGCTTCCTAGAGGTAGTAGTACCAGAGCAAGGCTAA

Upstream 100 bases:

>100_bases
AGCATAGTCAAATCCCACGCTTGCACAACAATAAAAGCTTTTTAAAGGGGCCAAGGGGTAGGCTAGAACCCGATAGAATA
GGTAGCCCGTAGACATATGG

Downstream 100 bases:

>100_bases
CCCTCTAAGAGGGCCGAAGTGGTGCGACAAGCTGGCTCCGAACTTGTTTTTACGTGTTTTTCATTTCACGCTCTTCTCGC
CCGCGCGTGCTCCCCTGGTT

Product: ABC-type dipeptide transport, periplasmic component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MGVVASRAALIAGIVVLVVIVAGIAVYFASKPEEKPAAPTEQPTEQPTTTPTEEKPAEEQPVQAAKPQLPPEVKVIEVSK
AVIAVAPKDVAVEDIVNAIDTKGKKLIIVRYEVDEENTKPVEESVGFSDINPAFYRNTTIDALIIAARKETNPEIREMLY
EAVYKLSNYEVPILWLGQYMLVRSQWSWVHGRYYHPTLAERYDLLWEDPAAPVKNLEFGGYKNDPSTYVIATIGWPDTFD
PAADYETFGWAIFHNIGDTLVTYWKDDTKEVIPDLAVAWVHDKEGTTWYFVIRGGVKAYDPWHNKVYDISAVDVLFTIWR
VARLGLDPSWMVTEFIDVNNSKVLTEEEFDQILAQGGLYADYKGQTIEPKSLKELLEFFGYDGETAGVVMLKLYMPYSPI
LSILSDPFLIVIPMKYLFDNVDELKGKYEEALEASQYGKNPAAWANYIGTGEQEPTHLYLHKYPIGTGPYYVAEYKEDSY
IVLKYNPYYWNKSLWYMEPYGKDGVPSHQTVIYLIANDHVTRLQIYKAGQADTAVVPLDRLDEVRDYKLQDNPQFKIEVE
TGGLEPAIVYIVLNANKEPFNNRLVRQALMYAIPFDQIKEVVYSGFLERLYGVIPAGFPGHNDDIVIKYTFDLDKAMELI
QKSGIDPTKYNIEIWYNEGNAQREQIATLLQQTWGQLGFKVGVKALNWPTLLSKTEKGDFDVYIIGWAPDYLDPDNYAGP
LFYGGTRFSFLEVVVPEQG

Sequences:

>Translated_739_residues
MGVVASRAALIAGIVVLVVIVAGIAVYFASKPEEKPAAPTEQPTEQPTTTPTEEKPAEEQPVQAAKPQLPPEVKVIEVSK
AVIAVAPKDVAVEDIVNAIDTKGKKLIIVRYEVDEENTKPVEESVGFSDINPAFYRNTTIDALIIAARKETNPEIREMLY
EAVYKLSNYEVPILWLGQYMLVRSQWSWVHGRYYHPTLAERYDLLWEDPAAPVKNLEFGGYKNDPSTYVIATIGWPDTFD
PAADYETFGWAIFHNIGDTLVTYWKDDTKEVIPDLAVAWVHDKEGTTWYFVIRGGVKAYDPWHNKVYDISAVDVLFTIWR
VARLGLDPSWMVTEFIDVNNSKVLTEEEFDQILAQGGLYADYKGQTIEPKSLKELLEFFGYDGETAGVVMLKLYMPYSPI
LSILSDPFLIVIPMKYLFDNVDELKGKYEEALEASQYGKNPAAWANYIGTGEQEPTHLYLHKYPIGTGPYYVAEYKEDSY
IVLKYNPYYWNKSLWYMEPYGKDGVPSHQTVIYLIANDHVTRLQIYKAGQADTAVVPLDRLDEVRDYKLQDNPQFKIEVE
TGGLEPAIVYIVLNANKEPFNNRLVRQALMYAIPFDQIKEVVYSGFLERLYGVIPAGFPGHNDDIVIKYTFDLDKAMELI
QKSGIDPTKYNIEIWYNEGNAQREQIATLLQQTWGQLGFKVGVKALNWPTLLSKTEKGDFDVYIIGWAPDYLDPDNYAGP
LFYGGTRFSFLEVVVPEQG
>Mature_738_residues
GVVASRAALIAGIVVLVVIVAGIAVYFASKPEEKPAAPTEQPTEQPTTTPTEEKPAEEQPVQAAKPQLPPEVKVIEVSKA
VIAVAPKDVAVEDIVNAIDTKGKKLIIVRYEVDEENTKPVEESVGFSDINPAFYRNTTIDALIIAARKETNPEIREMLYE
AVYKLSNYEVPILWLGQYMLVRSQWSWVHGRYYHPTLAERYDLLWEDPAAPVKNLEFGGYKNDPSTYVIATIGWPDTFDP
AADYETFGWAIFHNIGDTLVTYWKDDTKEVIPDLAVAWVHDKEGTTWYFVIRGGVKAYDPWHNKVYDISAVDVLFTIWRV
ARLGLDPSWMVTEFIDVNNSKVLTEEEFDQILAQGGLYADYKGQTIEPKSLKELLEFFGYDGETAGVVMLKLYMPYSPIL
SILSDPFLIVIPMKYLFDNVDELKGKYEEALEASQYGKNPAAWANYIGTGEQEPTHLYLHKYPIGTGPYYVAEYKEDSYI
VLKYNPYYWNKSLWYMEPYGKDGVPSHQTVIYLIANDHVTRLQIYKAGQADTAVVPLDRLDEVRDYKLQDNPQFKIEVET
GGLEPAIVYIVLNANKEPFNNRLVRQALMYAIPFDQIKEVVYSGFLERLYGVIPAGFPGHNDDIVIKYTFDLDKAMELIQ
KSGIDPTKYNIEIWYNEGNAQREQIATLLQQTWGQLGFKVGVKALNWPTLLSKTEKGDFDVYIIGWAPDYLDPDNYAGPL
FYGGTRFSFLEVVVPEQG

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=517, Percent_Identity=25.531914893617, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787762, Length=492, Percent_Identity=23.5772357723577, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787052, Length=269, Percent_Identity=23.7918215613383, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787551, Length=282, Percent_Identity=23.758865248227, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 83873; Mature: 83742

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVASRAALIAGIVVLVVIVAGIAVYFASKPEEKPAAPTEQPTEQPTTTPTEEKPAEEQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVQAAKPQLPPEVKVIEVSKAVIAVAPKDVAVEDIVNAIDTKGKKLIIVRYEVDEENTKP
CHHHCCCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
VEESVGFSDINPAFYRNTTIDALIIAARKETNPEIREMLYEAVYKLSNYEVPILWLGQYM
HHHHCCCCCCCCHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCH
LVRSQWSWVHGRYYHPTLAERYDLLWEDPAAPVKNLEFGGYKNDPSTYVIATIGWPDTFD
HHHCCCCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
PAADYETFGWAIFHNIGDTLVTYWKDDTKEVIPDLAVAWVHDKEGTTWYFVIRGGVKAYD
CCCCCCHHHHHHHHHHCCCEEEECCCCHHHHCCCEEEEEEECCCCCEEEEEEECCCCCCC
PWHNKVYDISAVDVLFTIWRVARLGLDPSWMVTEFIDVNNSKVLTEEEFDQILAQGGLYA
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEECHHHHHHHHHCCCEEE
DYKGQTIEPKSLKELLEFFGYDGETAGVVMLKLYMPYSPILSILSDPFLIVIPMKYLFDN
CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHCC
VDELKGKYEEALEASQYGKNPAAWANYIGTGEQEPTHLYLHKYPIGTGPYYVAEYKEDSY
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCE
IVLKYNPYYWNKSLWYMEPYGKDGVPSHQTVIYLIANDHVTRLQIYKAGQADTAVVPLDR
EEEEECCEEECCEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCEEEECHHH
LDEVRDYKLQDNPQFKIEVETGGLEPAIVYIVLNANKEPFNNRLVRQALMYAIPFDQIKE
HHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
VVYSGFLERLYGVIPAGFPGHNDDIVIKYTFDLDKAMELIQKSGIDPTKYNIEIWYNEGN
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCC
AQREQIATLLQQTWGQLGFKVGVKALNWPTLLSKTEKGDFDVYIIGWAPDYLDPDNYAGP
CHHHHHHHHHHHHHHHHCHHHCCEEECCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
LFYGGTRFSFLEVVVPEQG
EEECCCCEEEEEEEECCCC
>Mature Secondary Structure 
GVVASRAALIAGIVVLVVIVAGIAVYFASKPEEKPAAPTEQPTEQPTTTPTEEKPAEEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVQAAKPQLPPEVKVIEVSKAVIAVAPKDVAVEDIVNAIDTKGKKLIIVRYEVDEENTKP
CHHHCCCCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
VEESVGFSDINPAFYRNTTIDALIIAARKETNPEIREMLYEAVYKLSNYEVPILWLGQYM
HHHHCCCCCCCCHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCH
LVRSQWSWVHGRYYHPTLAERYDLLWEDPAAPVKNLEFGGYKNDPSTYVIATIGWPDTFD
HHHCCCCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
PAADYETFGWAIFHNIGDTLVTYWKDDTKEVIPDLAVAWVHDKEGTTWYFVIRGGVKAYD
CCCCCCHHHHHHHHHHCCCEEEECCCCHHHHCCCEEEEEEECCCCCEEEEEEECCCCCCC
PWHNKVYDISAVDVLFTIWRVARLGLDPSWMVTEFIDVNNSKVLTEEEFDQILAQGGLYA
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEECHHHHHHHHHCCCEEE
DYKGQTIEPKSLKELLEFFGYDGETAGVVMLKLYMPYSPILSILSDPFLIVIPMKYLFDN
CCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHCC
VDELKGKYEEALEASQYGKNPAAWANYIGTGEQEPTHLYLHKYPIGTGPYYVAEYKEDSY
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCE
IVLKYNPYYWNKSLWYMEPYGKDGVPSHQTVIYLIANDHVTRLQIYKAGQADTAVVPLDR
EEEEECCEEECCEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCEEEECHHH
LDEVRDYKLQDNPQFKIEVETGGLEPAIVYIVLNANKEPFNNRLVRQALMYAIPFDQIKE
HHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
VVYSGFLERLYGVIPAGFPGHNDDIVIKYTFDLDKAMELIQKSGIDPTKYNIEIWYNEGN
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCC
AQREQIATLLQQTWGQLGFKVGVKALNWPTLLSKTEKGDFDVYIIGWAPDYLDPDNYAGP
CHHHHHHHHHHHHHHHHCHHHCCEEECCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCC
LFYGGTRFSFLEVVVPEQG
EEECCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]