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The map label for this gene is ybeM [H]

Identifier: 124027487

GI number: 124027487

Start: 574346

End: 575164

Strand: Reverse

Name: ybeM [H]

Synonym: Hbut_0603

Alternate gene names: 124027487

Gene position: 575164-574346 (Counterclockwise)

Preceding gene: 124027488

Following gene: 124027485

Centisome position: 34.5

GC content: 57.39

Gene sequence:

>819_bases
GTGGCGCGGGTTAGGCTTGGCCTAGCCCAGTTTGAGGCTGGGCGCAGCGGGATTGAGAGTGGAGAGAGGCTCCGAAGACT
CCTCTCCCGCTACCGTGTCGAGGCCGACATTATAGTGCTACCCGAATACGGTAATGTGTATCCTGCTGGGCTCCGTGCAG
CCGAGGTAAGGGCTCGGGCTGAGAATCCCAAAGACTCTCCATTCATAAGGTTTCTCGAGGAAATTTCATCCGAGTATACG
GCTGTGATAGTCTCGGGGTTCCTTGAGCGGAGCGGGGACTGCGCCTACAGCTCCATAGTGATGGTGGAGCCGGGCAAGGA
GGTGCAAGTGGTTTACAGGAAGACAGTGCTCTTTGACGCGCTGGGCGTGAGGGAGTCAAAGAGCCTTTGCCGGGGTGAGC
AGCCGCCGCCGGTCCTCGAGGTGAGGGGGGTTCGGGTTGGGTTTATCGTGTGTTTTGAGCTGCGCTTTCCCGAGCTGGCT
CGCAGCCTGGCTCTCCGTGGCGCAGAGCTTGTAGCAGTACCAGCTGCCTGGTACCGTGGGAATCTCAAAGAGGAGCATCT
CCTCGTCACTGCTAGGTCTAGAGCTCTCGAAAACACAGTTTACCTTGCAGTAGCCTCGATGACTGGGCCGCACTTCACTG
GACGCAGCATACTCGTAGACCCAATGGGTGTTGTAAGGCTCGACCTGGGATCCGAGCCGGGCTACGCCGAGGTCGATGTA
GACCTGGACTACATTAATGAGGTGCGTAAGCAGCTCCCATTACTAGAGCTACAGCCCAGGGCATACGAGATATACACAAG
AGCTCTTAGGAGAGATTAG

Upstream 100 bases:

>100_bases
ACAGCTCTTTCATAAATACTTGCTGCTACATAGCCTCTTAGGGGCTGGAGCTGGAGAGAAATTCCTCACAACGCATGCCT
TTATTATGTGGTGCTGTGTA

Downstream 100 bases:

>100_bases
CATGTTACGCGTATCGTTATGCGAGTCCTAGTGCTACCAGCACTGGGTATACCGCTGTGGAATAGATTGCTGCAATCAGT
ATGACTTTCACTAGCTCGCG

Product: amidohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MARVRLGLAQFEAGRSGIESGERLRRLLSRYRVEADIIVLPEYGNVYPAGLRAAEVRARAENPKDSPFIRFLEEISSEYT
AVIVSGFLERSGDCAYSSIVMVEPGKEVQVVYRKTVLFDALGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFELRFPELA
RSLALRGAELVAVPAAWYRGNLKEEHLLVTARSRALENTVYLAVASMTGPHFTGRSILVDPMGVVRLDLGSEPGYAEVDV
DLDYINEVRKQLPLLELQPRAYEIYTRALRRD

Sequences:

>Translated_272_residues
MARVRLGLAQFEAGRSGIESGERLRRLLSRYRVEADIIVLPEYGNVYPAGLRAAEVRARAENPKDSPFIRFLEEISSEYT
AVIVSGFLERSGDCAYSSIVMVEPGKEVQVVYRKTVLFDALGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFELRFPELA
RSLALRGAELVAVPAAWYRGNLKEEHLLVTARSRALENTVYLAVASMTGPHFTGRSILVDPMGVVRLDLGSEPGYAEVDV
DLDYINEVRKQLPLLELQPRAYEIYTRALRRD
>Mature_271_residues
ARVRLGLAQFEAGRSGIESGERLRRLLSRYRVEADIIVLPEYGNVYPAGLRAAEVRARAENPKDSPFIRFLEEISSEYTA
VIVSGFLERSGDCAYSSIVMVEPGKEVQVVYRKTVLFDALGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFELRFPELAR
SLALRGAELVAVPAAWYRGNLKEEHLLVTARSRALENTVYLAVASMTGPHFTGRSILVDPMGVVRLDLGSEPGYAEVDVD
LDYINEVRKQLPLLELQPRAYEIYTRALRRD

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=190, Percent_Identity=31.5789473684211, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI297632348, Length=190, Percent_Identity=31.5789473684211, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI5031947, Length=190, Percent_Identity=31.5789473684211, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556280, Length=273, Percent_Identity=26.3736263736264, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323383, Length=254, Percent_Identity=31.1023622047244, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355835, Length=231, Percent_Identity=25.974025974026, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30458; Mature: 30326

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVRLGLAQFEAGRSGIESGERLRRLLSRYRVEADIIVLPEYGNVYPAGLRAAEVRARA
CCCEEECHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHC
ENPKDSPFIRFLEEISSEYTAVIVSGFLERSGDCAYSSIVMVEPGKEVQVVYRKTVLFDA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHH
LGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFELRFPELARSLALRGAELVAVPAAWYRG
HCCCCHHHHHCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHCCCEEEEECHHHHCC
NLKEEHLLVTARSRALENTVYLAVASMTGPHFTGRSILVDPMGVVRLDLGSEPGYAEVDV
CCCCCEEEEEEHHHHHCCEEEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEE
DLDYINEVRKQLPLLELQPRAYEIYTRALRRD
CHHHHHHHHHHCCCEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
ARVRLGLAQFEAGRSGIESGERLRRLLSRYRVEADIIVLPEYGNVYPAGLRAAEVRARA
CCEEECHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHC
ENPKDSPFIRFLEEISSEYTAVIVSGFLERSGDCAYSSIVMVEPGKEVQVVYRKTVLFDA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHH
LGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFELRFPELARSLALRGAELVAVPAAWYRG
HCCCCHHHHHCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHCCCEEEEECHHHHCC
NLKEEHLLVTARSRALENTVYLAVASMTGPHFTGRSILVDPMGVVRLDLGSEPGYAEVDV
CCCCCEEEEEEHHHHHCCEEEEEEEECCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEE
DLDYINEVRKQLPLLELQPRAYEIYTRALRRD
CHHHHHHHHHHCCCEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]